ethacrynic acid has been researched along with Hypoxia in 17 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ampullar endolymphatic potential (AEP) was studied in the guinea pig during ischemia and asphyxia and following systemic application of ethacrynic acid." | 3.65 | Effects of anoxia and ethacrynic acid upon ampullar endolymphatic potential and upon high energy phosphates in ampullar wall. ( Kusakari, J; Thalmann, R, 1976) |
| "During the episodes of hypoxemia, DPE thresholds were elevated by 10 dB while ABR thresholds were elevated by 22." | 1.29 | Effect of hypoxemia and ethacrynic acid on ABR and distortion product emission thresholds. ( Attias, J; Freeman, S; Furst, M; Goitein, K; Sohmer, H, 1995) |
| "Ethacrynic acid was used in dogs to change the concentration of sodium and potassium (meq/liter) in endolymph from 5." | 1.25 | The mutual independence of the endolymphatic potential and the concentrations of sodium and potassium in endolymph. ( Brusilow, SW; Gordes, E, 1973) |
| "Both haemorrhage and anoxia caused a rapid fall of p." | 1.25 | Factors influencing the electrical potential across the mucosa of rat colon. ( Edmonds, CJ; Marriott, J, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (70.59) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pond, BB | 1 |
| Galeffi, F | 1 |
| Ahrens, R | 1 |
| Schwartz-Bloom, RD | 1 |
| Freeman, S | 1 |
| Goitein, K | 1 |
| Attias, J | 1 |
| Furst, M | 1 |
| Sohmer, H | 1 |
| Wei, EP | 1 |
| Randad, RS | 1 |
| Levasseur, JE | 1 |
| Abraham, DJ | 1 |
| Kontos, HA | 1 |
| Gutman, Y | 1 |
| Wald, H | 1 |
| Czazkes, W | 1 |
| Johannesen, J | 1 |
| Lie, M | 1 |
| Kiil, F | 1 |
| Vosteen, KH | 1 |
| Kusakari, J | 1 |
| Thalmann, R | 1 |
| Whitehead, ML | 1 |
| Lonsbury-Martin, BL | 1 |
| Martin, GK | 1 |
| Tsujikawa, S | 1 |
| Ninoyu, O | 2 |
| Amano, H | 1 |
| Yamashita, T | 1 |
| Kumazawa, T | 1 |
| Syka, J | 1 |
| Melichar, I | 1 |
| Hommerich, C | 1 |
| Morgenstern, C | 1 |
| Del Castillo, JR | 1 |
| Whittembury, G | 1 |
| Mason, DT | 1 |
| Zelis, R | 1 |
| Lee, G | 1 |
| Hughes, JL | 1 |
| Spann, JF | 1 |
| Amsterdam, EA | 1 |
| Murray, DG | 1 |
| Racz, GB | 1 |
| Domm, BM | 1 |
| Vassallo, CL | 1 |
| Brusilow, SW | 1 |
| Gordes, E | 1 |
| Edmonds, CJ | 1 |
| Marriott, J | 1 |
1 review available for ethacrynic acid and Hypoxia
| Article | Year |
|---|---|
Current concepts and treatment of digitalis toxicity.
Topics: Adenosine Triphosphatases; Arrhythmias, Cardiac; Binding Sites; Biological Transport; Calcium; Catec | 1971 |
16 other studies available for ethacrynic acid and Hypoxia
| Article | Year |
|---|---|
Chloride transport inhibitors influence recovery from oxygen-glucose deprivation-induced cellular injury in adult hippocampus.
Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Bumetanide; Carrier Proteins; Cell Survival; Chlori | 2004 |
Effect of hypoxemia and ethacrynic acid on ABR and distortion product emission thresholds.
Topics: Animals; Auditory Threshold; Cats; Cochlear Microphonic Potentials; Diuretics; Ethacrynic Acid; Evok | 1995 |
Effect of local change in O2 saturation of hemoglobin on cerebral vasodilation from hypoxia and hypotension.
Topics: Animals; Arterioles; Cats; Cerebrovascular Circulation; Ethacrynic Acid; Hemoglobins; Hypotension; H | 1993 |
Differences in characteristics of ethacrynic acid accumulation in kidney cortex, medulla and papilla.
Topics: Animals; Ethacrynic Acid; Ethylmaleimide; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; | 1975 |
Renal energy metabolism and sodium reabsorption after 2,4-dinitrophenol administration.
Topics: Anaerobiosis; Animals; Cyanides; Dinitrophenols; Dogs; Energy Metabolism; Ethacrynic Acid; Female; H | 1977 |
[Formation of the inner ear lymphs. Permeability of inner ear membranes (author's transl)].
Topics: Animals; Ear, Inner; Endolymph; Ethacrynic Acid; Guinea Pigs; Hypoxia; Ion Exchange; Labyrinthine Fl | 1976 |
Effects of anoxia and ethacrynic acid upon ampullar endolymphatic potential and upon high energy phosphates in ampullar wall.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Ear, Inner; Energy Metabolism; Ethacrynic Acid; | 1976 |
Evidence for two discrete sources of 2f1-f2 distortion-product otoacoustic emission in rabbit. II: Differential physiological vulnerability.
Topics: Acoustic Stimulation; Acoustics; Animals; Audiometry; Auditory Fatigue; Cadaver; Ethacrynic Acid; Ge | 1992 |
Positive and negative DC potential in the vestibular system of pigeons.
Topics: Animals; Biological Transport, Active; Cochlear Duct; Columbidae; Endolymph; Ethacrynic Acid; Hypoxi | 1991 |
The effect of loop diuretics upon summating potentials in the guinea pig.
Topics: Animals; Cell Membrane Permeability; Cochlea; Ethacrynic Acid; Evoked Potentials; Furosemide; Guinea | 1985 |
Endolymph formation in the inner ear of pigeons.
Topics: Animals; Cochlea; Cochlear Microphonic Potentials; Columbidae; Endolymph; Ethacrynic Acid; Guinea Pi | 1987 |
Na+, K+ and Cl- transport in isolated small intestinal cells from guinea pig. Evidences for the existence of a second Na+ pump.
Topics: Animals; Chlorides; Cold Temperature; Ethacrynic Acid; Guinea Pigs; Hypoxia; Intestine, Small; Mathe | 1987 |
Fat-embolism syndrome (respiratory insufficiency syndrome). A rationale for treatment.
Topics: Adolescent; Adult; Alcohols; Dextrans; Diuresis; Embolism, Fat; Ethacrynic Acid; Female; Fractures, | 1974 |
Myxedema coma with respiratory failure.
Topics: Acidosis, Respiratory; Ampicillin; Coma; Digitalis Glycosides; Ethacrynic Acid; Humans; Hypoxia; Mal | 1973 |
The mutual independence of the endolymphatic potential and the concentrations of sodium and potassium in endolymph.
Topics: Animals; Cochlea; Dogs; Dose-Response Relationship, Drug; Ethacrynic Acid; Guinea Pigs; Hypoxia; Lab | 1973 |
Factors influencing the electrical potential across the mucosa of rat colon.
Topics: Acetazolamide; Adrenalectomy; Animals; Biological Transport, Active; Blood Vessels; Chlorides; Chlor | 1968 |