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ethacrynic acid and Hypokalemia

ethacrynic acid has been researched along with Hypokalemia in 44 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	44 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
SCHROEDER, G	1
SANNERSTEDT, R	1
WERKOE, L	1
MAHER, JF	1
SCHREINER, GE	1
Kayser, D	1
Hulter, HN	1
Toto, RD	1
Sebastian, A	1
Mackie, S	1
Cooke, CR	1
Wilson, TE	1
Melby, JC	1
Gross, DJ	1
Ben Chetrit, E	1
Stein, P	1
Rosler, A	1
Eliakim, M	1
Lumholtz, IB	1
Frohlich, ED	1
Werning, C	1
Fuchs, C	1
Hunneman, DH	1
Scheler, F	1
Schwartz, AB	1
Rose, JC	1
Rowe, WS	1
Greenberg, A	1
Sherlock, S	3
Senewiratne, B	3
Scott, A	2
Walker, JG	2
Gardner, JD	1
Lapey, A	1
Simopoulos, P	1
Bravo, EL	2
Barjon, P	1
Fourcade, J	1
Mimran, A	1
Berkman, M	1
Leemhuis, MP	1
Struyvenberg, A	1
Szachowski, J	1
Pawliszewska, J	1
Puchalska-Krotki, H	1
Martinez-Maldonado, M	1
Dustan, HR	1
Tarazi, RC	1
Imler, M	1
Bockel, R	1
Peter, B	1
Kieny, R	1
Stahl, J	1
Sánchez, A	1
Ikeda, T	1
Leiter, L	1
Riecker, G	1
Perez-Stable, EC	1
Materson, BJ	1
Anderton, JL	1
Kincaid-Smith, P	1
Reubi, FC	1
Yamauchi, M	1
Heidbreder, E	1
Hennemann, H	1
Krempien, B	1
Heidland, A	1
Sullivan, RC	1
Freemon, FR	1
Caranasos, GJ	1
Fort, AT	1
Morrison, JC	1
Fish, SA	1
Schmidt, P	1
Walker, WG	1
Lieberman, FL	1
Reynolds, TB	1
Rieselbach, RE	1
Buckalew, VM	1
Andrieu, J	1
Lesueur, G	1
Wayne, HH	1
Kotler, SA	1
McGirr, PS	1
Stoike, RD	1
Dige-Petersen, H	1

Reviews

8 reviews available for ethacrynic acid and Hypokalemia

Article	Year
Significance of hypokalaemia due to diuretics. The Netherlands journal of medicine, 1973, Volume: 16, Issue:1 Topics: Amiloride; Arrhythmias, Cardiac; Chlorothiazide; Diuretics; Ethacrynic Acid; Extracellular Space; Fu	1973
[Diuretics in refractory circulatory failure]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1974, Jun-01, Volume: 27, Issue:11 Topics: Dehydration; Diuretics; Edema; Ethacrynic Acid; Furosemide; Heart Failure; Hemodynamics; Humans; Hyp	1974
[Depletion therapy of chronic congestive heart failure]. Revista espanola de cardiologia, 1968, Volume: 21, Issue:2 Topics: Bloodletting; Carbonic Anhydrase Inhibitors; Chlorides; Diet, Sodium-Restricted; Digitalis Glycoside	1968
[Hypertension--diuretics as antihypertensive agents]. Nihon rinsho. Japanese journal of clinical medicine, 1970, Volume: 28, Issue:4 Topics: Aged; Antihypertensive Agents; Arthritis; Benzothiadiazines; Blood Pressure; Chlorothiazide; Chlorth	1970
Combinations of diuretics in the treatment of edema. American heart journal, 1970, Volume: 80, Issue:3 Topics: Acetazolamide; Benzothiadiazines; Chlorthalidone; Diuretics; Edema; Ethacrynic Acid; Furosemide; Glu	1970
Diuretic drug therapy of edema. The Medical clinics of North America, 1971, Volume: 55, Issue:2 Topics: Ambulatory Care; Ascites; Body Weight; Chlorides; Diuresis; Diuretics; Edema; Ethacrynic Acid; Furos	1971
Diuretics. II. Clinical considerations. Drugs, 1971, Volume: 1, Issue:2 Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I	1971
Combination diuretic drug therapy. Cardiovascular clinics, 1971, Volume: 2, Issue:3 Topics: Amiloride; Benzothiadiazines; Diet; Diuretics; Drug Therapy, Combination; Ethacrynic Acid; Furosemid	1971

Trials

3 trials available for ethacrynic acid and Hypokalemia

Article	Year
[Short and long term treatment of cardiac edemas with ethacrynic acid]. Deutsche medizinische Wochenschrift (1946), 1967, May-05, Volume: 92, Issue:18 Topics: Adult; Aged; Blood Pressure; Diuresis; Ethacrynic Acid; Female; Heart Failure; Humans; Hypokalemia;	1967
Extrarenal effects of diuretic agents. Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 4, Issue:1 Topics: Acidosis, Renal Tubular; Adipose Tissue; Alkalosis; Animals; Antihypertensive Agents; Blood Volume;	1970
The use of ethacrynic acid in patients with cirrhosis and ascites. Gastroenterology, 1965, Volume: 49, Issue:5 Topics: Alkalosis; Ascites; Clinical Trials as Topic; Ethacrynic Acid; Humans; Hypokalemia; Liver Cirrhosis	1965

Other Studies

33 other studies available for ethacrynic acid and Hypokalemia

Article	Year
CLINICAL EXPERIENCES WITH ETHACRYNIC ACID, A NEW NON-THIAZIDE SALURETIC AGENT (MK-595). Acta medica Scandinavica, 1964, Volume: 175 Topics: Aneurysm; Arteriosclerosis; Biomedical Research; Blood; Body Weight; Creatine; Creatinine; Diabetes	1964
STUDIES ON ETHACRYNIC ACID IN PATIENTS WITH REFRACTORY EDEMA. Annals of internal medicine, 1965, Volume: 62 Topics: Alkalosis; Blood; Chlorides; Creatine; Creatinine; Diuretics; Drug Therapy; Edema; Ethacrynic Acid;	1965
Effect of extracellular fluid volume depletion on renal regulation of acid-base and potassium equilibrium during prolonged mineral acid administration. The Journal of laboratory and clinical medicine, 1984, Volume: 103, Issue:6 Topics: Acid-Base Equilibrium; Acidosis; Aldosterone; Animals; Bicarbonates; Chlorides; Dogs; Ethacrynic Aci	1984
Edema associated with laxative abuse and excessive diuretic therapy. Israel journal of medical sciences, 1980, Volume: 16, Issue:11 Topics: Adult; Cathartics; Diet, Sodium-Restricted; Diuretics; Edema; Ethacrynic Acid; Female; Foot Diseases	1980
[Drug information: therapeutic main group: diuretics. 10. High-ceiling diuretics (furosemide, bumetanide, ethacrynic acid)]. Sygeplejersken, 1978, Dec-06, Volume: 78, Issue:48 Topics: Bumetanide; Diuretics; Drug Interactions; Ethacrynic Acid; Furosemide; Humans; Hypokalemia	1978
Editorial: Use and abuse of diuretics. American heart journal, 1975, Volume: 89, Issue:1 Topics: Benzothiadiazines; Diuretics; Edema; Ethacrynic Acid; Furosemide; Heart Failure; Humans; Hypertensio	1975
[The therapy of edematous diseases]. Fortschritte der Medizin, 1977, Aug-18, Volume: 95, Issue:31 Topics: Antihypertensive Agents; Bed Rest; Diabetes Insipidus; Diuretics; Diuretics, Osmotic; Edema; Ethacry	1977
[Hyperreninism without hyperaldosteronism in diuretic abuse: a report of a case with identification of mefruside and ethacrynic acid in urine (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1977, Sep-16, Volume: 102, Issue:37 Topics: Aldosterone; Diuretics; Ethacrynic Acid; Female; Humans; Hypokalemia; Mefruside; Metabolic Diseases;	1977
Diuretic-induced hypokalemia. American family physician, 1975, Volume: 11, Issue:1 Topics: Diuretics; Electrocardiography; Ethacrynic Acid; Furosemide; Humans; Hypokalemia; Kidney Tubules; Po	1975
Editorial: Diuretics. American family physician, 1975, Volume: 11, Issue:1 Topics: Diuretics; Drug Therapy, Combination; Ear Diseases; Ethacrynic Acid; Furosemide; Hypokalemia; Potass	1975
Some aspects of diuretic therapy. The Medical journal of Australia, 1975, Mar-22, Volume: 1, Issue:12 Topics: Aged; Amiloride; Benzothiadiazines; Digitalis Glycosides; Diuretics; Drug Therapy, Combination; Etha	1975
What's new in diuretic therapy. American family physician, 1986, Volume: 33, Issue:5 Topics: Acetazolamide; Acid-Base Imbalance; Biological Transport; Diuretics; Drug Resistance; Ethacrynic Aci	1986
Complications of diuretic therapy in hepatic cirrhosis. Lancet (London, England), 1966, May-14, Volume: 1, Issue:7446 Topics: Chlorothiazide; Diuretics; Ethacrynic Acid; Furosemide; Hepatic Encephalopathy; Humans; Hypokalemia;	1966
Amiloride ('MK 870') in patients with ascites due to cirrhosis of the liver. Lancet (London, England), 1968, Jan-20, Volume: 1, Issue:7534 Topics: Adult; Ascites; Bicarbonates; Creatinine; Diuretics; Ethacrynic Acid; Furosemide; Guanidines; Humans	1968
Abnormal membrane sodium transport in Liddle's syndrome. The Journal of clinical investigation, 1971, Volume: 50, Issue:11 Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Biological Transport; Cell Membrane; Child; Erythroc	1971
[Transient deafness and ethacrynic acid. Possible role of the changes in the composition of cochlear fluids]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1972, Mar-20, Volume: 48, Issue:14 Topics: Action Potentials; Ascites; Cochlea; Deafness; Ethacrynic Acid; Female; Humans; Hypokalemia; Labyrin	1972
[Treatment of heart failure in general medical practice. Principles to follow. Errors to avoid]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1972, Nov-26, Volume: 48, Issue:48 Topics: Bloodletting; Dehydration; Diet, Sodium-Restricted; Digitalis Glycosides; Diuretics; Drug Combinatio	1972
Electrolyte disturbances resulting from diuretic therapy. Texas medicine, 1973, Volume: 69, Issue:7 Topics: Acetazolamide; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hypercalcemia; Hypokalemia; Hyponatre	1973
Diuretic and diet treatment of hypertension. Archives of internal medicine, 1974, Volume: 133, Issue:6 Topics: Benzothiadiazines; Blood Volume; Chlorthalidone; Creatinine; Diet, Sodium-Restricted; Diuretics; Eth	1974
[Importance of hyperammoniemia of the renal origin in the pathogenesis of hepatic coma released in cirrhotic patients by diuretics generating hypokaliemia]. Pathologie-biologie, 1969, Volume: 17, Issue:1 Topics: Acetazolamide; Acid-Base Equilibrium; Alkalosis; Ammonia; Ascites; Chlorides; Chlorthalidone; Edema;	1969
[New diuretics--ethacrynic acid]. Nihon rinsho. Japanese journal of clinical medicine, 1970, Volume: 28, Issue:4 Topics: Acidosis; Animals; Ethacrynic Acid; Haplorhini; Humans; Hypokalemia	1970
[Salidiuretic therapy of renal tubular acidosis and its complications]. Deutsche medizinische Wochenschrift (1946), 1972, Oct-06, Volume: 97, Issue:40 Topics: Acidosis, Renal Tubular; Bicarbonates; Biopsy; Blood Chemical Analysis; Blood Gas Analysis; Bone and	1972
Complications from diuretic therapy with ethacrynic acid and furosemide. Southern medical journal, 1971, Volume: 64, Issue:7 Topics: Adult; Alkalosis; Blood Volume; Ethacrynic Acid; Female; Furosemide; Humans; Hypokalemia; Hyponatrem	1971
Iatrogenic hypokalemia of pregnancy by furosemide and ethacrynic acid. The Journal of reproductive medicine, 1971, Volume: 6, Issue:5 Topics: Adolescent; Adult; Alkalosis; Ethacrynic Acid; Female; Furosemide; Hearing Disorders; Humans; Hypoka	1971
[Diuresis and diuretics]. Wiener klinische Wochenschrift, 1971, Jun-25, Volume: 83, Issue:25 Topics: Acetazolamide; Acute Disease; Agranulocytosis; Anuria; Biological Transport; Blood Platelet Disorder	1971
Indications and contraindications for diuretic therapy. Annals of the New York Academy of Sciences, 1966, Nov-22, Volume: 139, Issue:2 Topics: Diuretics; Ethacrynic Acid; Female; Furosemide; Glomerular Filtration Rate; Hemodynamics; Humans; Hy	1966
The complications of diuretic therapy in patients with cirrhosis. Annals of the New York Academy of Sciences, 1966, Nov-22, Volume: 139, Issue:2 Topics: Alkalosis; Ascites; Blood Urea Nitrogen; Chlorothiazide; Ethacrynic Acid; Furosemide; Hepatic Enceph	1966
The new diuretics. Wisconsin medical journal, 1970, Volume: 69, Issue:7 Topics: Acetazolamide; Chlorothiazide; Diuresis; Diuretics; Edema; Ethacrynic Acid; Furosemide; Humans; Hypo	1970
Clinical usage of the newer diuretic agents. Journal of the Medical Association of Georgia, 1970, Volume: 59, Issue:10 Topics: Diuretics; Ethacrynic Acid; Furosemide; Humans; Hypokalemia; Kidney Diseases; Spironolactone; Triamt	1970
[Diuretics in cirrhosis. Accidents. Indications]. La Presse medicale, 1969, Mar-29, Volume: 77, Issue:16 Topics: Adrenal Cortex Hormones; Alkalosis; Blood Urea Nitrogen; Blood Volume; Diuretics; Edema; Ethacrynic	1969
Diuretics. II. Other drugs. British medical journal, 1969, Jul-26, Volume: 3, Issue:5664 Topics: Drug Synergism; Ethacrynic Acid; Furosemide; Humans; Hypokalemia; Spironolactone; Triamterene	1969
Ethacrynic acid. Use in ambulatory patients with resistant edema. The American journal of cardiology, 1965, Volume: 16, Issue:5 Topics: Adolescent; Adult; Aged; Blood; Chlorides; Edema; Electrolytes; Ethacrynic Acid; Female; Heart Failu	1965
[Ethacrynic acid and carbohydrate metabolism]. Nordisk medicin, 1966, Feb-03, Volume: 75, Issue:5 Topics: Carbohydrate Metabolism; Diabetes Mellitus; Ethacrynic Acid; Female; Humans; Hypokalemia; Male	1966