ethacrynic acid has been researched along with Hypernatremia in 3 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Hypernatremia: Excessive amount of sodium in the blood. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the effect of selective rise of plasma NaCl concentration (hypernatremia) on NaHCO3 reabsorption and associated NaCl reabsorption remaining during continuous ethacrynic acid infusion, hypertonic NaCl solution was infused in three groups of anesthetized volume-expanded dogs." | 3.67 | Hypernatremia inhibits NaHCO3 reabsorption and associated NaCl reabsorption in dogs. ( Hartmann, A; Kiil, F; Langberg, H; Mathisen, O; Ostensen, J, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Langberg, H | 1 |
| Hartmann, A | 1 |
| Ostensen, J | 1 |
| Mathisen, O | 1 |
| Kiil, F | 1 |
| Greenberg, A | 1 |
| Chodakowska, J | 1 |
| Filipecki, S | 1 |
3 other studies available for ethacrynic acid and Hypernatremia
| Article | Year |
|---|---|
Hypernatremia inhibits NaHCO3 reabsorption and associated NaCl reabsorption in dogs.
Topics: Acetazolamide; Acid-Base Equilibrium; Animals; Bicarbonates; Carbon Dioxide; Dogs; Ethacrynic Acid; | 1986 |
What's new in diuretic therapy.
Topics: Acetazolamide; Acid-Base Imbalance; Biological Transport; Diuretics; Drug Resistance; Ethacrynic Aci | 1986 |
Ethacrynic acid in patients with salt and water retention-a clinical appraisal.
Topics: Chlorides; Edema; Ethacrynic Acid; Heart Failure; Humans; Hypernatremia; Hyponatremia; Kidney Failur | 1968 |