ethacrynic acid has been researched along with Heart Diseases in 15 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bufalari, A | 1 |
| Meloni, G | 1 |
| Klein, W | 1 |
| Passath, A | 1 |
| Harpf, H | 1 |
| Dýcka, J | 1 |
| Havard, CW | 1 |
| Ragusa, G | 1 |
| Smilari, L | 1 |
| King, JF | 1 |
| Salel, AF | 1 |
| Amsterdam, EA | 1 |
| Massumi, RA | 1 |
| Zelis, R | 1 |
| Mason, DT | 1 |
| Richter, R | 1 |
| Hartai, A | 1 |
| Harrison, KA | 1 |
| Oelert, H | 1 |
| Vinogradov, AV | 1 |
| Kuz'mina, AE | 1 |
| Selye, H | 2 |
| Somogyi, A | 1 |
| Savoie, L | 1 |
| Sanna, GP | 1 |
| Young, BK | 1 |
| Haft, JI | 1 |
| Lesch, M | 1 |
| Caranasos, GJ | 1 |
| Mulholland, JH | 1 |
| Aravanis, C | 1 |
| Antonakis, E | 1 |
| Michaelides, G | 1 |
1 review available for ethacrynic acid and Heart Diseases
| Article | Year |
|---|---|
[Aldosterone and aldosterone antagonists in surgery].
Topics: Adult; Aldosterone; Blood Volume; Brain Edema; Cardiac Surgical Procedures; Child; Digitalis Glycosi | 1971 |
3 trials available for ethacrynic acid and Heart Diseases
| Article | Year |
|---|---|
[Comparative study on the saluretic activity of etacrynic acid and BAY g 2821 in patients with cardiac decompensation (author's transl)].
Topics: Diuretics; Ethacrynic Acid; Heart Diseases; Humans; Potassium; Pyrazoles; Sodium Chloride; Time Fact | 1977 |
[Clinical and experimental studies of a new diuretic: ethacrynic acid].
Topics: Clinical Trials as Topic; Ethacrynic Acid; Heart Diseases; Humans; Liver Cirrhosis | 1967 |
Controlled study comparing ethacrynic acid to mercaptomerin in the treatment of acute pulmonary edema.
Topics: Acute Disease; Adult; Aged; Creatinine; Diuresis; Ethacrynic Acid; Female; Heart Diseases; Humans; I | 1968 |
11 other studies available for ethacrynic acid and Heart Diseases
| Article | Year |
|---|---|
[The behavior of uricemia during treatment with spironolactone and with other diuretics].
Topics: Acetazolamide; Adolescent; Adult; Aged; Chlorthalidone; Clopamide; Diuretics; Ethacrynic Acid; Femal | 1967 |
Diuretics.
Topics: Benzothiadiazines; Blood; Chlorides; Diuretics; Diuretics, Osmotic; Edema; Ethacrynic Acid; Heart Di | 1974 |
[Behavior of ammoniemia during treatment with ethacrynic acid in cardiopathic patients with congestive circulatory failure].
Topics: Ammonia; Ethacrynic Acid; Heart Diseases; Heart Failure; Humans | 1972 |
Recent advances in therapy for refractory congestive heart failure.
Topics: Adrenal Cortex Hormones; Aminophylline; Cardiac Catheterization; Cardiomyopathies; Dextrothyroxine; | 1973 |
Ethacrynic acid in blood transfusion--its effects on plasma volume and urine flow in severe anaemia in pregnancy.
Topics: Anemia; Blood Transfusion; Blood Volume; Diuresis; Dye Dilution Technique; Edema; Ethacrynic Acid; F | 1968 |
[Effect of diuretics on renin activity in cardiac insufficiency].
Topics: Adolescent; Adult; Aged; Aortic Valve Insufficiency; Arrhythmias, Cardiac; Arteriosclerosis; Coronar | 1971 |
Prevention of stress-induced cardiac necrosis by amiloride.
Topics: Animals; Diuretics; Ethacrynic Acid; Female; Heart Diseases; Hydrochlorothiazide; Immobilization; My | 1969 |
[Modern and rational use of diuretics in cardiology].
Topics: Coronary Disease; Diuretics; Ethacrynic Acid; Furosemide; Glucocorticoids; Heart Diseases; Humans; K | 1969 |
Treatment of pulmonary edema with ethacrynic acid during labor.
Topics: Adult; Ethacrynic Acid; Female; Heart Diseases; Humans; Obstetric Labor Complications; Pregnancy; Pr | 1970 |
Effect of various diuretics upon experimental cardiac necrosis.
Topics: Adrenal Cortex Hormones; Animals; Diuretics; Ethacrynic Acid; Guanidines; Heart Diseases; Hydrochlor | 1969 |
[Clinical experience with a new and potent diuretic (ethacrynic acid)].
Topics: Adolescent; Adult; Aged; Ethacrynic Acid; Female; Heart Diseases; Heart Failure; Humans; Male; Middl | 1966 |