ethacrynic acid has been researched along with Granulocytic Leukemia, Chronic in 2 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yenigül, M | 1 |
| Akçok, İ | 1 |
| Gencer Akçok, EB | 1 |
| Twentyman, PR | 1 |
| Lambert, E | 1 |
| Müller, M | 1 |
| Rees, JK | 1 |
2 other studies available for ethacrynic acid and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Ethacrynic acid and cinnamic acid combination exhibits selective anticancer effects on K562 chronic myeloid leukemia cells.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Cinnamates; Ethacrynic Acid; Humans; K562 Cel | 2022 |
Selective toxicity of ethacrynic acid towards lymphocytes of chronic lymphocytic leukemia in vitro.
Topics: Cell Survival; Dose-Response Relationship, Drug; Ethacrynic Acid; Humans; In Vitro Techniques; Leuke | 1992 |