ethacrynic acid has been researched along with E coli Infections in 2 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clofibric acid (CL) is a compound used to control hypertriglyceridemia, and ethacrynic acid (ET) is administered to enhance diuresis." | 1.33 | Aryloxoalcanoic compounds induce resistance to antibiotic therapy in urinary tract infection caused by Escherichia coli. ( Balagué, C; De Duffard, AM; De Ruiz, CS; Duffard, R; Nader-Macías, ME; Rey, R; Stürtz, N, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balagué, CE | 1 |
| de Ruiz, CS | 2 |
| Rey, R | 2 |
| de Duffard, AM | 2 |
| Nader-Macías, ME | 2 |
| Balagué, C | 1 |
| Stürtz, N | 1 |
| Duffard, R | 1 |
2 other studies available for ethacrynic acid and E coli Infections
| Article | Year |
|---|---|
Clofibric and ethacrynic acids prevent experimental pyelonephritis by Escherichia coli in mice.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Bacterial Adhesion; Clofibric Acid; Escherich | 2004 |
Aryloxoalcanoic compounds induce resistance to antibiotic therapy in urinary tract infection caused by Escherichia coli.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Clofibric Acid; Disease Models, Animal; Diuretics; Drug Int | 2006 |