ethacrynic acid has been researched along with Distorted Hearing in 31 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (90.32) | 18.7374 |
| 1990's | 2 (6.45) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meredith, MA | 1 |
| Allman, BL | 1 |
| Koechel, DA | 1 |
| Rybak, LP | 1 |
| Bartolami, S | 1 |
| Planche, M | 1 |
| Pujol, R | 1 |
| Iaroshevich, VI | 1 |
| Brown, RD | 1 |
| Feldman, AM | 1 |
| Gessler, U | 1 |
| Kameyama, T | 1 |
| Nabeshima, T | 1 |
| Takahashi, K | 1 |
| Tiedemann, R | 1 |
| Nakai, Y | 1 |
| Wagner, WH | 1 |
| Sheffield, PA | 1 |
| Turner, JS | 1 |
| Paparella, MM | 1 |
| Cooperman, LB | 1 |
| Rubin, IL | 1 |
| Ch'en, CL | 1 |
| Falk, SA | 1 |
| Kjellstrand, CM | 1 |
| Carmody, JP | 1 |
| Sauer, EP | 1 |
| Gladney, J | 1 |
| West, BA | 1 |
| Brummett, RE | 1 |
| Himes, DL | 1 |
| Federspil, P | 2 |
| Mausen, H | 1 |
| D'Arcy, PF | 1 |
| Harpur, ES | 1 |
| Walloch, RA | 1 |
| Anthony, J | 1 |
| Gibbons, N | 1 |
| Fort, AT | 2 |
| Morrison, JC | 2 |
| Fish, SA | 2 |
| Stenbaek, O | 1 |
| Quick, CA | 1 |
| Duvall, AJ | 1 |
| Matz, GJ | 1 |
| Naunton, RF | 1 |
5 reviews available for ethacrynic acid and Distorted Hearing
| Article | Year |
|---|---|
Ethacrynic acid and related diuretics: relationship of structure to beneficial and detrimental actions.
Topics: Animals; Antihypertensive Agents; Biotransformation; Blood Proteins; Diuretics; Ethacrynic Acid; Hea | 1981 |
Ototoxicity of loop diuretics.
Topics: Animals; Bumetanide; Cochlea; Diuretics; Ethacrynic Acid; Furosemide; Hearing Disorders; Humans | 1993 |
Pharmacology of hearing and ototoxicity.
Topics: Adrenal Glands; Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bumetanid | 1978 |
Toxicity of ethacrynic acid and furosemide.
Topics: Anemia; Animals; Cochlea; Diarrhea; Diuresis; Erythema Multiforme; Ethacrynic Acid; Furosemide; Gast | 1973 |
[Clinical use of diuretics].
Topics: Acid-Base Equilibrium; Benzothiadiazines; Diuretics; Ethacrynic Acid; Furosemide; Hearing Disorders; | 1974 |
26 other studies available for ethacrynic acid and Distorted Hearing
| Article | Year |
|---|---|
Early hearing-impairment results in crossmodal reorganization of ferret core auditory cortex.
Topics: Acoustic Stimulation; Animals; Anti-Bacterial Agents; Auditory Cortex; Auditory Threshold; Diuretics | 2012 |
Inhibition of the carbachol-evoked synthesis of inositol phosphates by ototoxic drugs in the rat cochlea.
Topics: Amikacin; Animals; Carbachol; Cell Death; Cisplatin; Cochlea; Ethacrynic Acid; Hearing Disorders; In | 1993 |
[Ototoxicity of some drug agents].
Topics: Age Factors; Aminoglycosides; Bleomycin; Cochlea; Deafness; Dimethyl Sulfoxide; Dose-Response Relati | 1975 |
[Diuretics].
Topics: Diuretics; Edema; Ethacrynic Acid; Furosemide; Glomerular Filtration Rate; Hearing Disorders; Humans | 1978 |
[Application of a response duration schedule in rats to evaluate drug-induced auditory impairment (author's transl)].
Topics: Acoustic Stimulation; Animals; Auditory Threshold; Discrimination Learning; Ethacrynic Acid; Hearing | 1978 |
[The conservative treatment of inner ear diseases. A survey of the actual possibilities (author's transl)].
Topics: Anti-Bacterial Agents; Deafness; Diuretics; Edema; Ethacrynic Acid; Hair Cells, Auditory; Hearing Di | 1978 |
Combined effect of 3', 4'-dideoxykanamycin B and potent diuretics on the cochlea. (A scanning and transmission electron microscopic evaluation).
Topics: Animals; Cochlea; Dibekacin; Drug Synergism; Ethacrynic Acid; Furosemide; Guinea Pigs; Hair Cells, A | 1977 |
[Ototoxicity of Aminoglycoside Antibiotics (author's transl)].
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Ethacrynic Acid; Guinea Pigs; Hearing Disorders; Hu | 1975 |
Ototoxic drugs: a review of clinical aspects, histopathologic changes and mechanisms of action.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Aspirin; Chloroquine; Cochlea; Dihydrostreptomycin Su | 1971 |
The dizzy patient.
Topics: Diazepam; Drainage; Ear; Ear Neoplasms; Ethacrynic Acid; Gentamicins; Hearing Disorders; Humans; Inf | 1972 |
Combined effects of noise and ototoxic drugs.
Topics: Animals; Anti-Bacterial Agents; Cochlea; Diuretics; Environmental Exposure; Ethacrynic Acid; Furosem | 1972 |
Ethacrynic acid in acute tubular necrosis. Indications and effect on the natural course.
Topics: Acute Kidney Injury; Aged; Child, Preschool; Ethacrynic Acid; Hearing Disorders; Humans; Kidney; Mid | 1972 |
Reversible hearing loss due to ethacrynic acid in occult renal failure. Case report.
Topics: Aged; Diabetic Nephropathies; Ethacrynic Acid; Female; Hearing Disorders; Humans; Kidney Failure, Ch | 1973 |
Interaction of kanamycin and ethacrynic acid. Severe cochlear damage in guinea pigs.
Topics: Acoustic Stimulation; Action Potentials; Animals; Cochlea; Drug Interactions; Epithelial Cells; Epit | 1973 |
[Experimental studies on ototoxicity of a potent diuretic (ethacrynic acid)].
Topics: Animals; Disease Models, Animal; Ethacrynic Acid; Guinea Pigs; Hearing Disorders; Injections, Intrav | 1973 |
Laboratory testing for ototoxic effects of drugs.
Topics: Animals; Ear Diseases; Ethacrynic Acid; Furosemide; Hearing Disorders; Hearing Tests; Kanamycin; Mic | 1973 |
Depression of the evoked cortical potential by ethacrynic acid.
Topics: Animals; Auditory Cortex; Auditory Threshold; Depression, Chemical; Ethacrynic Acid; Evoked Potentia | 1974 |
Iatrogenic hypokalemia of pregnancy by furosemide and ethacrynic acid.
Topics: Adolescent; Adult; Alkalosis; Ethacrynic Acid; Female; Furosemide; Hearing Disorders; Humans; Hypoka | 1971 |
[Adverse effects of interest].
Topics: Contraceptives, Oral; Ethacrynic Acid; Furosemide; Griseofulvin; Hearing Disorders; Humans; Jaundice | 1971 |
[Review of observed gentamicin ototoxicity cases in Germany].
Topics: Adolescent; Adult; Aged; Diabetes Complications; Drug Synergism; Ethacrynic Acid; Gentamicins; Germa | 1971 |
[Ethacrynic acid and hearing disorders].
Topics: Ear, Inner; Ethacrynic Acid; Hearing Disorders; Humans | 1971 |
[A report about drug side effects. X].
Topics: Adolescent; Adult; Amenorrhea; Chemical and Drug Induced Liver Injury; Contraceptives, Oral; Erythro | 1969 |
[Hearing disorders after treatment with ethacrynic acid (Edecrin) in patients with reduced kidney function].
Topics: Adult; Anuria; Ethacrynic Acid; Female; Hearing Disorders; Humans; Male; Middle Aged | 1970 |
Early changes in the cochlear duct from ethacrynic acid: an electronmicroscopie evaluation.
Topics: Animals; Atrophy; Cochlea; Edema; Electrolytes; Ethacrynic Acid; Guinea Pigs; Hearing Disorders; Hum | 1970 |
Case report. Diuretic induced ototoxicity in preeclampsia.
Topics: Adult; Ethacrynic Acid; Female; Furosemide; Hearing Disorders; Humans; Kidney Function Tests; Pre-Ec | 1971 |
Ototoxic drugs and poor renal function.
Topics: Animals; Audiometry; Cats; Cochlea; Ethacrynic Acid; Hearing Disorders; Humans; Kanamycin; Kidney; K | 1968 |