ethacrynic acid has been researched along with Diseases, Metabolic in 2 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ouabain-sensitive and the ethacrynic acid-sensitive sodium efflux from erythrocytes of patients with cystic fibrosis are both decreased." | 3.64 | Red-cell transport defect in patients with cystic fibrosis and in their parents. ( Balfe, JW; Cole, C; Welt, LG, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fuchs, C | 1 |
| Hunneman, DH | 1 |
| Scheler, F | 1 |
| Balfe, JW | 1 |
| Cole, C | 1 |
| Welt, LG | 1 |
2 other studies available for ethacrynic acid and Diseases, Metabolic
| Article | Year |
|---|---|
[Hyperreninism without hyperaldosteronism in diuretic abuse: a report of a case with identification of mefruside and ethacrynic acid in urine (author's transl)].
Topics: Aldosterone; Diuretics; Ethacrynic Acid; Female; Humans; Hypokalemia; Mefruside; Metabolic Diseases; | 1977 |
Red-cell transport defect in patients with cystic fibrosis and in their parents.
Topics: Adenosine Triphosphatases; Biological Transport, Active; Counseling; Cystic Fibrosis; Erythrocytes; | 1968 |