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ethacrynic acid and Diabetic Nephropathies

ethacrynic acid has been researched along with Diabetic Nephropathies in 3 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HAGEDORN, CW1
KAPLAN, AA1
HULET, WH1
Carmody, JP1
Sauer, EP1
Gladney, J1
Hwang, YS1

Other Studies

3 other studies available for ethacrynic acid and Diabetic Nephropathies

ArticleYear
PROLONGED ADMINISTRATION OF ETHACRYNIC ACID IN PATIENTS WITH CHRONIC RENAL DISEASE.
    The New England journal of medicine, 1965, Jun-03, Volume: 272

    Topics: Acid-Base Equilibrium; Diabetic Nephropathies; Diarrhea; Diuretics; Drug Therapy; Edema; Ethacrynic

1965
Reversible hearing loss due to ethacrynic acid in occult renal failure. Case report.
    Missouri medicine, 1973, Volume: 70, Issue:5

    Topics: Aged; Diabetic Nephropathies; Ethacrynic Acid; Female; Hearing Disorders; Humans; Kidney Failure, Ch

1973
[The diuretic activity of ethacrynic acid].
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1969, Jul-28, Volume: 68, Issue:7

    Topics: Adolescent; Adult; Diabetic Nephropathies; Diuresis; Electrocardiography; Ethacrynic Acid; Female; H

1969