ethacrynic acid has been researched along with Diabetic Nephropathies in 3 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
HAGEDORN, CW | 1 |
KAPLAN, AA | 1 |
HULET, WH | 1 |
Carmody, JP | 1 |
Sauer, EP | 1 |
Gladney, J | 1 |
Hwang, YS | 1 |
3 other studies available for ethacrynic acid and Diabetic Nephropathies
Article | Year |
---|---|
PROLONGED ADMINISTRATION OF ETHACRYNIC ACID IN PATIENTS WITH CHRONIC RENAL DISEASE.
Topics: Acid-Base Equilibrium; Diabetic Nephropathies; Diarrhea; Diuretics; Drug Therapy; Edema; Ethacrynic | 1965 |
Reversible hearing loss due to ethacrynic acid in occult renal failure. Case report.
Topics: Aged; Diabetic Nephropathies; Ethacrynic Acid; Female; Hearing Disorders; Humans; Kidney Failure, Ch | 1973 |
[The diuretic activity of ethacrynic acid].
Topics: Adolescent; Adult; Diabetic Nephropathies; Diuresis; Electrocardiography; Ethacrynic Acid; Female; H | 1969 |