ethacrynic acid has been researched along with Corneal Edema in 2 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Corneal Edema: An excessive amount of fluid in the cornea due to damage of the epithelium or endothelium causing decreased visual acuity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the effect of topical ethacrynic acid on rabbit and monkey intraocular pressure." | 7.68 | Effects of topical ethacrynic acid adducts on intraocular pressure in rabbits and monkeys. ( Epstein, DL; Epstein, MP; Schroeder, A; Tingey, DP, 1992) |
| "We evaluated the effect of topical ethacrynic acid on rabbit and monkey intraocular pressure." | 3.68 | Effects of topical ethacrynic acid adducts on intraocular pressure in rabbits and monkeys. ( Epstein, DL; Epstein, MP; Schroeder, A; Tingey, DP, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tingey, DP | 2 |
| Schroeder, A | 2 |
| Epstein, MP | 1 |
| Epstein, DL | 2 |
| Ozment, RR | 1 |
2 other studies available for ethacrynic acid and Corneal Edema
| Article | Year |
|---|---|
Effects of topical ethacrynic acid adducts on intraocular pressure in rabbits and monkeys.
Topics: Acetylcysteine; Animals; Corneal Edema; Dose-Response Relationship, Drug; Drug Combinations; Ethacry | 1992 |
The effect of intracameral ethacrynic acid on the intraocular pressure of living monkeys.
Topics: Animals; Anterior Eye Segment; Corneal Edema; Ethacrynic Acid; Injections; Intraocular Pressure; Mac | 1992 |