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ethacrynic acid and Chronic Kidney Failure

ethacrynic acid has been researched along with Chronic Kidney Failure in 38 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Research Excerpts

ExcerptRelevanceReference
"Administration of diuretics during acute renal failure in animals has been demonstrated to be of value with mannitol and/or loop-blocking diuretics, furosemide or ethacrynic acid."1.27The use of diuretics in varying degrees of renal impairment: an overview. ( Dickerman, D; Lowenthal, DT, 1983)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199037 (97.37)18.7374
1990's0 (0.00)18.2507
2000's1 (2.63)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wall, GC1
Bigner, D1
Craig, S1
Edwards, KD1
Sinnett, PF1
Stewart, JH1
Lowenthal, DT1
Dickerman, D1
Plouvier, B1
Haftel, Y1
François, M1
Hatron, PY1
Lemaire, P1
Devulder, B1
Gessler, U1
White, RP1
Canavese, JC1
Fabre, J1
Ravera, R1
Pillay, VK1
Schwartz, FD1
Aimi, K1
Kark, RM1
Guédon, J1
Legrain, M1
Cier, JF1
Sassard, J1
Zech, P1
Vincent, M1
Gharib, C1
Kennedy, AC1
Takasu, T1
Kawaguchi, Y2
Ogura, Y1
Kimura, Y1
Sakai, S1
Yamamoto, M1
Tanaka, S1
Oda, Y1
Carmody, JP1
Sauer, EP1
Gladney, J1
Fishback, DB1
Underwood, F1
Bennett, WM1
Tucker, RM1
Hunt, JC1
Levin, NW1
Anderton, JL1
Kincaid-Smith, P1
Schmidt, P1
Federspil, P1
Kleeman, CR1
Okun, R1
Heller, RJ1
Muth, RG1
Lao, M1
Zaleski, A1
Rieselbach, RE1
Chaffee, WG1
Merrill, JP1
Quellhorst, E2
Scheler, F2
Krecke, HJ1
Klein, H1
Uhse, HG1
Krück, F1
Zucchelli, P1
Petrella, A1
Fusaroli, M1
Sasdelli, M1
Melica, A1
Henning, HV1
Mietzsch, G1
Stegemann, I1
Chodakowska, J1
Filipecki, S1
Andrieu, J1
Lesueur, G1

Reviews

5 reviews available for ethacrynic acid and Chronic Kidney Failure

ArticleYear
Ethacrynic acid and the sulfa-sensitive patient.
    Archives of internal medicine, 2003, Jan-13, Volume: 163, Issue:1

    Topics: Aged; Diuretics; Drug Administration Schedule; Drug Hypersensitivity; Ethacrynic Acid; Heart Failure

2003
[Effects of potent diuretics in renal failure].
    Nihon rinsho. Japanese journal of clinical medicine, 1974, Volume: 32, Issue:8

    Topics: Acute Kidney Injury; Benzoates; Butylamines; Diuresis; Diuretics; Dose-Response Relationship, Drug;

1974
Recent advances in the medical and surgical treatment of hypertension.
    The Medical clinics of North America, 1968, Volume: 52, Issue:5

    Topics: Adrenocortical Hyperfunction; Antihypertensive Agents; Diet, Sodium-Restricted; Diuretics; Ethacryni

1968
Furosemide and ethacrynic acid in renal insufficiency.
    The Medical clinics of North America, 1971, Volume: 55, Issue:1

    Topics: Acute Kidney Injury; Adult; Animals; Dogs; Ethacrynic Acid; Furosemide; Humans; Kidney; Kidney Failu

1971
Diuretics. II. Clinical considerations.
    Drugs, 1971, Volume: 1, Issue:2

    Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I

1971

Trials

1 trial available for ethacrynic acid and Chronic Kidney Failure

ArticleYear
[Benzbromarone in the treatment of hyperuricemias].
    Minerva medica, 1975, Mar-07, Volume: 66, Issue:17

    Topics: Adult; Aged; Benzofurans; Clinical Trials as Topic; Drug Evaluation; Drug Tolerance; Ethacrynic Acid

1975

Other Studies

32 other studies available for ethacrynic acid and Chronic Kidney Failure

ArticleYear
Ethacrynic acid: assessment of saluretic and diuretic potency in patients with severe chronic renal failure.
    The Medical journal of Australia, 1967, Feb-25, Volume: 1, Issue:8

    Topics: Adult; Aged; Bendroflumethiazide; Blood Urea Nitrogen; Body Weight; Chlorides; Creatine; Diuretics;

1967
The use of diuretics in varying degrees of renal impairment: an overview.
    Clinical and experimental hypertension. Part A, Theory and practice, 1983, Volume: 5, Issue:2

    Topics: Acute Kidney Injury; Bumetanide; Diuretics; Ethacrynic Acid; Furosemide; Humans; Kidney Failure, Chr

1983
[Action of ethacrynic acid on the movement of phosphorus in the kidneys].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1978, Volume: 23, Issue:3

    Topics: Adult; Ethacrynic Acid; Humans; Kidney; Kidney Failure, Chronic; Male; Phosphorus

1978
[Diuretics].
    Fortschritte der Medizin, 1978, Jun-15, Volume: 96, Issue:23

    Topics: Diuretics; Edema; Ethacrynic Acid; Furosemide; Glomerular Filtration Rate; Hearing Disorders; Humans

1978
Antihypertensive agents in renal disease.
    The American journal of medicine, 1977, Volume: 62, Issue:4

    Topics: Antihypertensive Agents; Body Water; Clonidine; Diazoxide; Ethacrynic Acid; Furosemide; Guanethidine

1977
[The diuretics in the treatment of arteriol hypertension].
    Therapeutische Umschau. Revue therapeutique, 1976, Volume: 33, Issue:5

    Topics: Amiloride; Benzothiadiazines; Chlorthalidone; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hypert

1976
Transient and permanent deafness following treatment with ethacrynic acid in renal failure.
    Lancet (London, England), 1969, Jan-11, Volume: 1, Issue:7585

    Topics: Adult; Amphetamine; Aortic Valve Insufficiency; Aspartate Aminotransferases; Blood Urea Nitrogen; Ca

1969
Diuretics in chronic renal insufficiency.
    Advances in nephrology from the Necker Hospital, 1972, Volume: 2

    Topics: Dose-Response Relationship, Drug; Ethacrynic Acid; Furosemide; Humans; Kidney Failure, Chronic; Neph

1972
[Influence of ion factors on the pressor action of exogenous angiotensin in humans].
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 178, Issue:2

    Topics: Angiotensin II; Blood Pressure; Ethacrynic Acid; Humans; Hypertension, Renal; Ions; Kidney Failure,

1969
Editorial: Frusemide.
    Scottish medical journal, 1974, Volume: 19 Suppl 1

    Topics: Ethacrynic Acid; Furosemide; Hypertension; Kidney Failure, Chronic; Loop of Henle; Potassium; Propra

1974
[My prescription of diuretics].
    Nihon rinsho. Japanese journal of clinical medicine, 1974, Volume: 32, Issue:8

    Topics: Acute Kidney Injury; Benzothiadiazines; Diuretics; Edema; Ethacrynic Acid; Furosemide; Humans; Hyper

1974
[Kidney failure and diuretics--effectivity of the so-called potent diuretics].
    Nihon Jinzo Gakkai shi, 1974, Volume: 16, Issue:5

    Topics: Bumetanide; Diuretics; Ethacrynic Acid; Furosemide; Humans; Kidney Failure, Chronic

1974
Reversible hearing loss due to ethacrynic acid in occult renal failure. Case report.
    Missouri medicine, 1973, Volume: 70, Issue:5

    Topics: Aged; Diabetic Nephropathies; Ethacrynic Acid; Female; Hearing Disorders; Humans; Kidney Failure, Ch

1973
Fluorescein circulation time and the treatment of hypertension in the aged.
    Journal of the American Geriatrics Society, 1973, Volume: 21, Issue:11

    Topics: Adult; Age Factors; Aged; Blood Circulation Time; Blood Pressure; Carbamates; Ethacrynic Acid; Femal

1973
Ethylene glycol intoxication. Prevention of renal failure by aggressive management.
    JAMA, 1973, Dec-17, Volume: 226, Issue:12

    Topics: Acute Kidney Injury; Adult; Bicarbonates; Ethacrynic Acid; Ethanol; Ethylenes; Glycols; Hematuria; H

1973
[High doses of diuretics in renal insufficiency].
    Minerva medica, 1971, Oct-17, Volume: 62, Issue:78

    Topics: Acute Kidney Injury; Diuretics; Ethacrynic Acid; Furosemide; Humans; Injections, Intravenous; Kidney

1971
[High doses of diuretics in renal insufficiency].
    Il Policlinico. Sezione pratica, 1971, Aug-15, Volume: 78, Issue:16

    Topics: Acute Kidney Injury; Diuretics; Ethacrynic Acid; Furosemide; Humans; Injections, Intravenous; Kidney

1971
[Diuresis and diuretics].
    Wiener klinische Wochenschrift, 1971, Jun-25, Volume: 83, Issue:25

    Topics: Acetazolamide; Acute Disease; Agranulocytosis; Anuria; Biological Transport; Blood Platelet Disorder

1971
[Review of observed gentamicin ototoxicity cases in Germany].
    HNO, 1971, Volume: 19, Issue:11

    Topics: Adolescent; Adult; Aged; Diabetes Complications; Drug Synergism; Ethacrynic Acid; Gentamicins; Germa

1971
The renal regulation of sodium and potassium in patients with chronic renal failure (CRF) and the effect of diuretics on the excretion of these ions.
    Annals of the New York Academy of Sciences, 1966, Nov-22, Volume: 139, Issue:2

    Topics: Acetazolamide; Adult; Diuretics; Ethacrynic Acid; Female; Furosemide; Glomerular Filtration Rate; Hu

1966
Diuretics in renal disease.
    Medical times, 1969, Volume: 97, Issue:10

    Topics: Adult; Diuresis; Diuretics; Ethacrynic Acid; Female; Furosemide; Humans; Kidney Diseases; Kidney Fai

1969
[Ototoxicity of ethacrynic acid in patients with reduced kidney function].
    Ugeskrift for laeger, 1970, Apr-23, Volume: 132, Issue:17

    Topics: Cochlea; Ethacrynic Acid; Hearing; Humans; Injections, Intravenous; Kidney Failure, Chronic

1970
[Comparative evaluation of the effect of diuretics in renal diseases].
    Polskie Archiwum Medycyny Wewnetrznej, 1970, Volume: 44, Issue:6

    Topics: Diuretics; Ethacrynic Acid; Furosemide; Humans; Kidney Failure, Chronic; Natriuresis; Sulfonic Acids

1970
The new diuretics.
    Wisconsin medical journal, 1970, Volume: 69, Issue:7

    Topics: Acetazolamide; Chlorothiazide; Diuresis; Diuretics; Edema; Ethacrynic Acid; Furosemide; Humans; Hypo

1970
Hazards of ethacrynic acid.
    JAMA, 1970, Apr-06, Volume: 212, Issue:1

    Topics: Deafness; Ethacrynic Acid; Humans; Kidney; Kidney Failure, Chronic

1970
Hazards of ethacrynic acid.
    JAMA, 1970, Apr-06, Volume: 212, Issue:1

    Topics: Deafness; Ethacrynic Acid; Humans; Kidney; Kidney Failure, Chronic

1970
[The effectivness of ethacrynic acid, amiloride HCl and aldadiene K in kidney insufficiency].
    Klinische Wochenschrift, 1970, Apr-15, Volume: 48, Issue:8

    Topics: Administration, Oral; Adult; Body Weight; Calcium; Creatinine; Diuretics; Drug Synergism; Ethacrynic

1970
[Renal hemodynamics, electrolyte excretion and acid-base equilibrium in an acute human experiment with ethacrynic acid].
    Klinische Wochenschrift, 1971, Apr-01, Volume: 49, Issue:7

    Topics: Acid-Base Equilibrium; Acute Kidney Injury; Adolescent; Adult; Aged; Aminohippuric Acids; Ethacrynic

1971
[Ethacrynic acid: research on the mechanism of action and clinical use].
    Minerva medica, 1968, Jan-17, Volume: 59, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Diabetes Insipidus; Diuresis; Edema; Ethacrynic Acid; Female; Heart

1968
[Improvement of acidosis treatment in chronic kidney failure using ethacrynic acid].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1968, Volume: 74

    Topics: Acidosis, Renal Tubular; Creatinine; Ethacrynic Acid; Humans; Kidney Failure, Chronic

1968
Ethacrynic acid in patients with salt and water retention-a clinical appraisal.
    Polish medical journal, 1968, Volume: 7, Issue:4

    Topics: Chlorides; Edema; Ethacrynic Acid; Heart Failure; Humans; Hypernatremia; Hyponatremia; Kidney Failur

1968
[Diuretics in cirrhosis. Accidents. Indications].
    La Presse medicale, 1969, Mar-29, Volume: 77, Issue:16

    Topics: Adrenal Cortex Hormones; Alkalosis; Blood Urea Nitrogen; Blood Volume; Diuretics; Edema; Ethacrynic

1969