ethacrynic acid has been researched along with Chronic Kidney Failure in 38 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of diuretics during acute renal failure in animals has been demonstrated to be of value with mannitol and/or loop-blocking diuretics, furosemide or ethacrynic acid." | 1.27 | The use of diuretics in varying degrees of renal impairment: an overview. ( Dickerman, D; Lowenthal, DT, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (97.37) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.63) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wall, GC | 1 |
| Bigner, D | 1 |
| Craig, S | 1 |
| Edwards, KD | 1 |
| Sinnett, PF | 1 |
| Stewart, JH | 1 |
| Lowenthal, DT | 1 |
| Dickerman, D | 1 |
| Plouvier, B | 1 |
| Haftel, Y | 1 |
| François, M | 1 |
| Hatron, PY | 1 |
| Lemaire, P | 1 |
| Devulder, B | 1 |
| Gessler, U | 1 |
| White, RP | 1 |
| Canavese, JC | 1 |
| Fabre, J | 1 |
| Ravera, R | 1 |
| Pillay, VK | 1 |
| Schwartz, FD | 1 |
| Aimi, K | 1 |
| Kark, RM | 1 |
| Guédon, J | 1 |
| Legrain, M | 1 |
| Cier, JF | 1 |
| Sassard, J | 1 |
| Zech, P | 1 |
| Vincent, M | 1 |
| Gharib, C | 1 |
| Kennedy, AC | 1 |
| Takasu, T | 1 |
| Kawaguchi, Y | 2 |
| Ogura, Y | 1 |
| Kimura, Y | 1 |
| Sakai, S | 1 |
| Yamamoto, M | 1 |
| Tanaka, S | 1 |
| Oda, Y | 1 |
| Carmody, JP | 1 |
| Sauer, EP | 1 |
| Gladney, J | 1 |
| Fishback, DB | 1 |
| Underwood, F | 1 |
| Bennett, WM | 1 |
| Tucker, RM | 1 |
| Hunt, JC | 1 |
| Levin, NW | 1 |
| Anderton, JL | 1 |
| Kincaid-Smith, P | 1 |
| Schmidt, P | 1 |
| Federspil, P | 1 |
| Kleeman, CR | 1 |
| Okun, R | 1 |
| Heller, RJ | 1 |
| Muth, RG | 1 |
| Lao, M | 1 |
| Zaleski, A | 1 |
| Rieselbach, RE | 1 |
| Chaffee, WG | 1 |
| Merrill, JP | 1 |
| Quellhorst, E | 2 |
| Scheler, F | 2 |
| Krecke, HJ | 1 |
| Klein, H | 1 |
| Uhse, HG | 1 |
| Krück, F | 1 |
| Zucchelli, P | 1 |
| Petrella, A | 1 |
| Fusaroli, M | 1 |
| Sasdelli, M | 1 |
| Melica, A | 1 |
| Henning, HV | 1 |
| Mietzsch, G | 1 |
| Stegemann, I | 1 |
| Chodakowska, J | 1 |
| Filipecki, S | 1 |
| Andrieu, J | 1 |
| Lesueur, G | 1 |
5 reviews available for ethacrynic acid and Chronic Kidney Failure
| Article | Year |
|---|---|
Ethacrynic acid and the sulfa-sensitive patient.
Topics: Aged; Diuretics; Drug Administration Schedule; Drug Hypersensitivity; Ethacrynic Acid; Heart Failure | 2003 |
[Effects of potent diuretics in renal failure].
Topics: Acute Kidney Injury; Benzoates; Butylamines; Diuresis; Diuretics; Dose-Response Relationship, Drug; | 1974 |
Recent advances in the medical and surgical treatment of hypertension.
Topics: Adrenocortical Hyperfunction; Antihypertensive Agents; Diet, Sodium-Restricted; Diuretics; Ethacryni | 1968 |
Furosemide and ethacrynic acid in renal insufficiency.
Topics: Acute Kidney Injury; Adult; Animals; Dogs; Ethacrynic Acid; Furosemide; Humans; Kidney; Kidney Failu | 1971 |
Diuretics. II. Clinical considerations.
Topics: Administration, Oral; Aminophylline; Ascites; Calcium; Carbohydrate Metabolism; Carbonic Anhydrase I | 1971 |
1 trial available for ethacrynic acid and Chronic Kidney Failure
| Article | Year |
|---|---|
[Benzbromarone in the treatment of hyperuricemias].
Topics: Adult; Aged; Benzofurans; Clinical Trials as Topic; Drug Evaluation; Drug Tolerance; Ethacrynic Acid | 1975 |
32 other studies available for ethacrynic acid and Chronic Kidney Failure
| Article | Year |
|---|---|
Ethacrynic acid: assessment of saluretic and diuretic potency in patients with severe chronic renal failure.
Topics: Adult; Aged; Bendroflumethiazide; Blood Urea Nitrogen; Body Weight; Chlorides; Creatine; Diuretics; | 1967 |
The use of diuretics in varying degrees of renal impairment: an overview.
Topics: Acute Kidney Injury; Bumetanide; Diuretics; Ethacrynic Acid; Furosemide; Humans; Kidney Failure, Chr | 1983 |
[Action of ethacrynic acid on the movement of phosphorus in the kidneys].
Topics: Adult; Ethacrynic Acid; Humans; Kidney; Kidney Failure, Chronic; Male; Phosphorus | 1978 |
[Diuretics].
Topics: Diuretics; Edema; Ethacrynic Acid; Furosemide; Glomerular Filtration Rate; Hearing Disorders; Humans | 1978 |
Antihypertensive agents in renal disease.
Topics: Antihypertensive Agents; Body Water; Clonidine; Diazoxide; Ethacrynic Acid; Furosemide; Guanethidine | 1977 |
[The diuretics in the treatment of arteriol hypertension].
Topics: Amiloride; Benzothiadiazines; Chlorthalidone; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hypert | 1976 |
Transient and permanent deafness following treatment with ethacrynic acid in renal failure.
Topics: Adult; Amphetamine; Aortic Valve Insufficiency; Aspartate Aminotransferases; Blood Urea Nitrogen; Ca | 1969 |
Diuretics in chronic renal insufficiency.
Topics: Dose-Response Relationship, Drug; Ethacrynic Acid; Furosemide; Humans; Kidney Failure, Chronic; Neph | 1972 |
[Influence of ion factors on the pressor action of exogenous angiotensin in humans].
Topics: Angiotensin II; Blood Pressure; Ethacrynic Acid; Humans; Hypertension, Renal; Ions; Kidney Failure, | 1969 |
Editorial: Frusemide.
Topics: Ethacrynic Acid; Furosemide; Hypertension; Kidney Failure, Chronic; Loop of Henle; Potassium; Propra | 1974 |
[My prescription of diuretics].
Topics: Acute Kidney Injury; Benzothiadiazines; Diuretics; Edema; Ethacrynic Acid; Furosemide; Humans; Hyper | 1974 |
[Kidney failure and diuretics--effectivity of the so-called potent diuretics].
Topics: Bumetanide; Diuretics; Ethacrynic Acid; Furosemide; Humans; Kidney Failure, Chronic | 1974 |
Reversible hearing loss due to ethacrynic acid in occult renal failure. Case report.
Topics: Aged; Diabetic Nephropathies; Ethacrynic Acid; Female; Hearing Disorders; Humans; Kidney Failure, Ch | 1973 |
Fluorescein circulation time and the treatment of hypertension in the aged.
Topics: Adult; Age Factors; Aged; Blood Circulation Time; Blood Pressure; Carbamates; Ethacrynic Acid; Femal | 1973 |
Ethylene glycol intoxication. Prevention of renal failure by aggressive management.
Topics: Acute Kidney Injury; Adult; Bicarbonates; Ethacrynic Acid; Ethanol; Ethylenes; Glycols; Hematuria; H | 1973 |
[High doses of diuretics in renal insufficiency].
Topics: Acute Kidney Injury; Diuretics; Ethacrynic Acid; Furosemide; Humans; Injections, Intravenous; Kidney | 1971 |
[High doses of diuretics in renal insufficiency].
Topics: Acute Kidney Injury; Diuretics; Ethacrynic Acid; Furosemide; Humans; Injections, Intravenous; Kidney | 1971 |
[Diuresis and diuretics].
Topics: Acetazolamide; Acute Disease; Agranulocytosis; Anuria; Biological Transport; Blood Platelet Disorder | 1971 |
[Review of observed gentamicin ototoxicity cases in Germany].
Topics: Adolescent; Adult; Aged; Diabetes Complications; Drug Synergism; Ethacrynic Acid; Gentamicins; Germa | 1971 |
The renal regulation of sodium and potassium in patients with chronic renal failure (CRF) and the effect of diuretics on the excretion of these ions.
Topics: Acetazolamide; Adult; Diuretics; Ethacrynic Acid; Female; Furosemide; Glomerular Filtration Rate; Hu | 1966 |
Diuretics in renal disease.
Topics: Adult; Diuresis; Diuretics; Ethacrynic Acid; Female; Furosemide; Humans; Kidney Diseases; Kidney Fai | 1969 |
[Ototoxicity of ethacrynic acid in patients with reduced kidney function].
Topics: Cochlea; Ethacrynic Acid; Hearing; Humans; Injections, Intravenous; Kidney Failure, Chronic | 1970 |
[Comparative evaluation of the effect of diuretics in renal diseases].
Topics: Diuretics; Ethacrynic Acid; Furosemide; Humans; Kidney Failure, Chronic; Natriuresis; Sulfonic Acids | 1970 |
The new diuretics.
Topics: Acetazolamide; Chlorothiazide; Diuresis; Diuretics; Edema; Ethacrynic Acid; Furosemide; Humans; Hypo | 1970 |
Hazards of ethacrynic acid.
Topics: Deafness; Ethacrynic Acid; Humans; Kidney; Kidney Failure, Chronic | 1970 |
Hazards of ethacrynic acid.
Topics: Deafness; Ethacrynic Acid; Humans; Kidney; Kidney Failure, Chronic | 1970 |
[The effectivness of ethacrynic acid, amiloride HCl and aldadiene K in kidney insufficiency].
Topics: Administration, Oral; Adult; Body Weight; Calcium; Creatinine; Diuretics; Drug Synergism; Ethacrynic | 1970 |
[Renal hemodynamics, electrolyte excretion and acid-base equilibrium in an acute human experiment with ethacrynic acid].
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Adolescent; Adult; Aged; Aminohippuric Acids; Ethacrynic | 1971 |
[Ethacrynic acid: research on the mechanism of action and clinical use].
Topics: Adolescent; Adult; Aged; Child; Diabetes Insipidus; Diuresis; Edema; Ethacrynic Acid; Female; Heart | 1968 |
[Improvement of acidosis treatment in chronic kidney failure using ethacrynic acid].
Topics: Acidosis, Renal Tubular; Creatinine; Ethacrynic Acid; Humans; Kidney Failure, Chronic | 1968 |
Ethacrynic acid in patients with salt and water retention-a clinical appraisal.
Topics: Chlorides; Edema; Ethacrynic Acid; Heart Failure; Humans; Hypernatremia; Hyponatremia; Kidney Failur | 1968 |
[Diuretics in cirrhosis. Accidents. Indications].
Topics: Adrenal Cortex Hormones; Alkalosis; Blood Urea Nitrogen; Blood Volume; Diuretics; Edema; Ethacrynic | 1969 |