ethacrynic acid has been researched along with Cholestasis in 3 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Corbett, CL | 1 |
| Bartholomew, TC | 1 |
| Billing, BH | 1 |
| Summerfield, JA | 1 |
| Peterlik, M | 1 |
| Czok, G | 1 |
| Schulze, PJ | 1 |
3 other studies available for ethacrynic acid and Cholestasis
| Article | Year |
|---|---|
Urinary excretion of bile acids in cholestasis: evidence for renal tubular secretion in man.
Topics: Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Ethacrynic Acid; Female; Furosemide; | 1981 |
[Experimental cholestasis by dibucaine and harmaline: effects on bile flow and hepatic transport of bile acids, ethacrynic acid and ouabain (author's transl)].
Topics: Alkaloids; Animals; Bile; Bile Acids and Salts; Cell Membrane Permeability; Cholestasis; Dibucaine; | 1977 |
[Choleretic effect of ethacrynic acid in the rat].
Topics: Animals; Bile Acids and Salts; Chlorides; Cholagogues and Choleretics; Cholestasis; Chromatography; | 1973 |