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ethacrynic acid and Cardiac Hypertrophy

ethacrynic acid has been researched along with Cardiac Hypertrophy in 2 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pillay, VK1
Schwartz, FD1
Aimi, K1
Kark, RM1
Goldring, D1
Hernandez, A1
Hartmann, AF1

Other Studies

2 other studies available for ethacrynic acid and Cardiac Hypertrophy

ArticleYear
Transient and permanent deafness following treatment with ethacrynic acid in renal failure.
    Lancet (London, England), 1969, Jan-11, Volume: 1, Issue:7585

    Topics: Adult; Amphetamine; Aortic Valve Insufficiency; Aspartate Aminotransferases; Blood Urea Nitrogen; Ca

1969
The critically ill child: care of the infant in cardiac failure.
    Pediatrics, 1971, Volume: 47, Issue:6

    Topics: Acidosis, Respiratory; Age Factors; Arrhythmias, Cardiac; Cardiac Catheterization; Cardiomegaly; Cya

1971