ethacrynic acid has been researched along with Brain Swelling in 13 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute cerebral edema was created in dogs by the intracarotid injection of sodium lauryl sulfate, a method that produces no structural or vascular disruption in the brain." | 1.25 | Diuretic synergy in the treatment of acute experimental cerebral edema. ( Austin, G; Wepsic, JG; Wilkinson, HA, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wyrick, SD | 1 |
| Smith, FT | 1 |
| Kemp, WE | 1 |
| Grippo, AA | 1 |
| Wilkinson, HA | 1 |
| Wepsic, JG | 1 |
| Austin, G | 1 |
| Bourke, RS | 1 |
| Waldman, JB | 1 |
| Kimelberg, HK | 1 |
| Barron, KD | 1 |
| San Filippo, BD | 1 |
| Popp, AJ | 1 |
| Nelson, LR | 1 |
| de los Reyes, RA | 1 |
| Ausman, JI | 1 |
| Diaz, FG | 1 |
| Reulen, HJ | 1 |
| Kandel', EI | 1 |
| Chebotareva, NM | 1 |
| Baethmann, A | 1 |
| Lanksch, W | 1 |
| Schmiedek, P | 1 |
| Jahrmärker, H | 1 |
| Oelert, H | 1 |
| Schmidt, P | 1 |
| Miyazaki, Y | 1 |
| Suematsu, K | 1 |
| Nakamura, J | 1 |
| Gottstein, U | 1 |
| Sacrez, R | 1 |
| Geisert, J | 1 |
| Willard, D | 1 |
5 reviews available for ethacrynic acid and Brain Swelling
| Article | Year |
|---|---|
Agents for cerebral edema.
Topics: Acetazolamide; Adult; Animals; Barbiturates; Brain Edema; Child; Dexamethasone; Ethacrynic Acid; Fur | 1981 |
Vasogenic brain oedema. New aspects in its formation, resolution and therapy.
Topics: Brain Abscess; Brain Edema; Brain Neoplasms; Capillary Permeability; Cerebrovascular Circulation; Ce | 1976 |
[Prevention and treatment of cerebral edema using current drugs].
Topics: Adrenal Cortex Hormones; Brain Edema; Diuretics; Ethacrynic Acid; Ganglionic Blockers; Glucose; Glyc | 1972 |
[When and which diuretics? General and specific indications for diuretic therapy].
Topics: Acid-Base Equilibrium; Brain Edema; Diuresis; Diuretics; Edema; Ethacrynic Acid; Furosemide; Humans; | 1971 |
[Aldosterone and aldosterone antagonists in surgery].
Topics: Adult; Aldosterone; Blood Volume; Brain Edema; Cardiac Surgical Procedures; Child; Digitalis Glycosi | 1971 |
8 other studies available for ethacrynic acid and Brain Swelling
| Article | Year |
|---|---|
Effects of [(N-alkyl-1,3-dioxo-1H,3H-isoindolin-5-yl)oxy]alkanoic acids, [(N-alkyl-1-oxo-1H,3H-isoindolin-5-yl)oxy]butanoic acids, and related derivatives on chloride influx in primary astroglial cultures.
Topics: Animals; Brain Edema; Butyrates; Cats; Cells, Cultured; Cerebral Cortex; Chlorides; Craniocerebral T | 1987 |
Diuretic synergy in the treatment of acute experimental cerebral edema.
Topics: Animals; Brain Edema; Diuretics; Diuretics, Osmotic; Dogs; Drug Synergism; Ethacrynic Acid; Intracra | 1971 |
Adenosine-stimulated astroglial swelling in cat cerebral cortex in vivo with total inhibition by a non-diuretic acylaryloxyacid derivative.
Topics: Adenosine; Animals; Brain Edema; Cats; Cerebrospinal Fluid; Chlorides; Ethacrynic Acid; Ion Channels | 1981 |
Formation and treatment of cerebral edema.
Topics: Aldosterone; Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Dexamethasone; Ethacrynic Ac | 1974 |
[Diuresis and diuretics].
Topics: Acetazolamide; Acute Disease; Agranulocytosis; Anuria; Biological Transport; Blood Platelet Disorder | 1971 |
Effect of ethacrynic acid on lowering of intracranial pressure.
Topics: Adolescent; Adult; Brain Edema; Brain Neoplasms; Child; Chlorides; Craniocerebral Trauma; Depression | 1969 |
[Therapy of cerebral circulatory disorders].
Topics: Brain Edema; Cerebral Angiography; Cerebral Hemorrhage; Cerebrovascular Circulation; Cerebrovascular | 1968 |
[Place of new diuretics in the treatment of some neonatal diseases].
Topics: Brain Edema; Diuresis; Edema; Ethacrynic Acid; Furosemide; Humans; Infant, Newborn; Infant, Newborn, | 1969 |