ethacrynic acid has been researched along with B16 Melanoma in 1 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melphalan was the most effective individual drug, followed by lomustine, fotemustine, and 4-HA." | 1.30 | The effects of different antineoplastic agents and of pretreatment by modulators on three melanoma lines. ( Canteras-Jordana, M; Rodriguez-Vicente, J; Vicente-Ortega, V, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodriguez-Vicente, J | 1 |
| Vicente-Ortega, V | 1 |
| Canteras-Jordana, M | 1 |
1 other study available for ethacrynic acid and B16 Melanoma
| Article | Year |
|---|---|
The effects of different antineoplastic agents and of pretreatment by modulators on three melanoma lines.
Topics: Animals; Anisoles; Antineoplastic Agents; Buthionine Sulfoximine; Dicarboxylic Acids; Dose-Response | 1998 |