ethacrynic acid has been researched along with Aura in 5 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suzukawa, J | 2 |
| Omori, K | 2 |
| Yang, L | 1 |
| Inagaki, C | 2 |
| Margineanu, DG | 1 |
| Klitgaard, H | 1 |
| Frey, HH | 1 |
| Okugawa, G | 1 |
| Fujiseki, Y | 1 |
| Heizmann, CW | 1 |
| Delgado-Escueta, AV | 1 |
5 other studies available for ethacrynic acid and Aura
| Article | Year |
|---|---|
Continuous administration of antisense oligonucleotides to c-fos reduced the development of seizure susceptibility after ethacrynic acid-induced seizure in mice.
Topics: Animals; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Epilepsy; Ethacryn | 2003 |
Differential effects of cation-chloride co-transport-blocking diuretics in a rat hippocampal slice model of epilepsy.
Topics: Animals; Anticonvulsants; Bumetanide; Disease Models, Animal; Diuretics; Dose-Response Relationship, | 2006 |
Antiepileptic effect of loop diuretics? Comment to "Differential effects of cation-chloride co-transport-blocking diuretics in a rat hippocampal slice model of epilepsy" by Margineanu, Klitgaard, Epilepsy Res. 69 (2006) 93-99.
Topics: Animals; Bumetanide; Diuretics; Epilepsy; Ethacrynic Acid; Evoked Potentials; Furosemide; Rats | 2006 |
Long-lasting c-fos and NGF mRNA expressions and loss of perikaryal parvalbumin immunoreactivity in the development of epileptogenesis after ethacrynic acid-induced seizure.
Topics: Animals; Convulsants; Disease Susceptibility; Epilepsy; Ethacrynic Acid; Excitatory Amino Acid Antag | 1999 |
Sodium outflux and influx within nerve terminals from chronic epileptogenic foci.
Topics: Acetylcholinesterase; Animals; Biological Transport, Active; Cats; Cerebral Cortex; Epilepsy; Ethacr | 1979 |