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ethacrynic acid and Anoxemia

ethacrynic acid has been researched along with Anoxemia in 17 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Research Excerpts

ExcerptRelevanceReference
"The ampullar endolymphatic potential (AEP) was studied in the guinea pig during ischemia and asphyxia and following systemic application of ethacrynic acid."3.65Effects of anoxia and ethacrynic acid upon ampullar endolymphatic potential and upon high energy phosphates in ampullar wall. ( Kusakari, J; Thalmann, R, 1976)
"During the episodes of hypoxemia, DPE thresholds were elevated by 10 dB while ABR thresholds were elevated by 22."1.29Effect of hypoxemia and ethacrynic acid on ABR and distortion product emission thresholds. ( Attias, J; Freeman, S; Furst, M; Goitein, K; Sohmer, H, 1995)
"Ethacrynic acid was used in dogs to change the concentration of sodium and potassium (meq/liter) in endolymph from 5."1.25The mutual independence of the endolymphatic potential and the concentrations of sodium and potassium in endolymph. ( Brusilow, SW; Gordes, E, 1973)
"Both haemorrhage and anoxia caused a rapid fall of p."1.25Factors influencing the electrical potential across the mucosa of rat colon. ( Edmonds, CJ; Marriott, J, 1968)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199012 (70.59)18.7374
1990's4 (23.53)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pond, BB1
Galeffi, F1
Ahrens, R1
Schwartz-Bloom, RD1
Freeman, S1
Goitein, K1
Attias, J1
Furst, M1
Sohmer, H1
Wei, EP1
Randad, RS1
Levasseur, JE1
Abraham, DJ1
Kontos, HA1
Gutman, Y1
Wald, H1
Czazkes, W1
Johannesen, J1
Lie, M1
Kiil, F1
Vosteen, KH1
Kusakari, J1
Thalmann, R1
Whitehead, ML1
Lonsbury-Martin, BL1
Martin, GK1
Tsujikawa, S1
Ninoyu, O2
Amano, H1
Yamashita, T1
Kumazawa, T1
Syka, J1
Melichar, I1
Hommerich, C1
Morgenstern, C1
Del Castillo, JR1
Whittembury, G1
Mason, DT1
Zelis, R1
Lee, G1
Hughes, JL1
Spann, JF1
Amsterdam, EA1
Murray, DG1
Racz, GB1
Domm, BM1
Vassallo, CL1
Brusilow, SW1
Gordes, E1
Edmonds, CJ1
Marriott, J1

Reviews

1 review available for ethacrynic acid and Anoxemia

ArticleYear
Current concepts and treatment of digitalis toxicity.
    The American journal of cardiology, 1971, Volume: 27, Issue:5

    Topics: Adenosine Triphosphatases; Arrhythmias, Cardiac; Binding Sites; Biological Transport; Calcium; Catec

1971

Other Studies

16 other studies available for ethacrynic acid and Anoxemia

ArticleYear
Chloride transport inhibitors influence recovery from oxygen-glucose deprivation-induced cellular injury in adult hippocampus.
    Neuropharmacology, 2004, Volume: 47, Issue:2

    Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Bumetanide; Carrier Proteins; Cell Survival; Chlori

2004
Effect of hypoxemia and ethacrynic acid on ABR and distortion product emission thresholds.
    Journal of the neurological sciences, 1995, Volume: 131, Issue:1

    Topics: Animals; Auditory Threshold; Cats; Cochlear Microphonic Potentials; Diuretics; Ethacrynic Acid; Evok

1995
Effect of local change in O2 saturation of hemoglobin on cerebral vasodilation from hypoxia and hypotension.
    The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 2

    Topics: Animals; Arterioles; Cats; Cerebrovascular Circulation; Ethacrynic Acid; Hemoglobins; Hypotension; H

1993
Differences in characteristics of ethacrynic acid accumulation in kidney cortex, medulla and papilla.
    Biochemical pharmacology, 1975, Apr-01, Volume: 24, Issue:7

    Topics: Animals; Ethacrynic Acid; Ethylmaleimide; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques;

1975
Renal energy metabolism and sodium reabsorption after 2,4-dinitrophenol administration.
    The American journal of physiology, 1977, Volume: 233, Issue:3

    Topics: Anaerobiosis; Animals; Cyanides; Dinitrophenols; Dogs; Energy Metabolism; Ethacrynic Acid; Female; H

1977
[Formation of the inner ear lymphs. Permeability of inner ear membranes (author's transl)].
    Archives of oto-rhino-laryngology, 1976, Sep-16, Volume: 212, Issue:4

    Topics: Animals; Ear, Inner; Endolymph; Ethacrynic Acid; Guinea Pigs; Hypoxia; Ion Exchange; Labyrinthine Fl

1976
Effects of anoxia and ethacrynic acid upon ampullar endolymphatic potential and upon high energy phosphates in ampullar wall.
    The Laryngoscope, 1976, Volume: 86, Issue:1

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Ear, Inner; Energy Metabolism; Ethacrynic Acid;

1976
Evidence for two discrete sources of 2f1-f2 distortion-product otoacoustic emission in rabbit. II: Differential physiological vulnerability.
    The Journal of the Acoustical Society of America, 1992, Volume: 92, Issue:5

    Topics: Acoustic Stimulation; Acoustics; Animals; Audiometry; Auditory Fatigue; Cadaver; Ethacrynic Acid; Ge

1992
Positive and negative DC potential in the vestibular system of pigeons.
    ORL; journal for oto-rhino-laryngology and its related specialties, 1991, Volume: 53, Issue:1

    Topics: Animals; Biological Transport, Active; Cochlear Duct; Columbidae; Endolymph; Ethacrynic Acid; Hypoxi

1991
The effect of loop diuretics upon summating potentials in the guinea pig.
    Hearing research, 1985, Volume: 20, Issue:3

    Topics: Animals; Cell Membrane Permeability; Cochlea; Ethacrynic Acid; Evoked Potentials; Furosemide; Guinea

1985
Endolymph formation in the inner ear of pigeons.
    ORL; journal for oto-rhino-laryngology and its related specialties, 1987, Volume: 49, Issue:1

    Topics: Animals; Cochlea; Cochlear Microphonic Potentials; Columbidae; Endolymph; Ethacrynic Acid; Guinea Pi

1987
Na+, K+ and Cl- transport in isolated small intestinal cells from guinea pig. Evidences for the existence of a second Na+ pump.
    Biochimica et biophysica acta, 1987, Jul-23, Volume: 901, Issue:2

    Topics: Animals; Chlorides; Cold Temperature; Ethacrynic Acid; Guinea Pigs; Hypoxia; Intestine, Small; Mathe

1987
Fat-embolism syndrome (respiratory insufficiency syndrome). A rationale for treatment.
    The Journal of bone and joint surgery. American volume, 1974, Volume: 56, Issue:7

    Topics: Adolescent; Adult; Alcohols; Dextrans; Diuresis; Embolism, Fat; Ethacrynic Acid; Female; Fractures,

1974
Myxedema coma with respiratory failure.
    The American review of respiratory disease, 1973, Volume: 107, Issue:5

    Topics: Acidosis, Respiratory; Ampicillin; Coma; Digitalis Glycosides; Ethacrynic Acid; Humans; Hypoxia; Mal

1973
The mutual independence of the endolymphatic potential and the concentrations of sodium and potassium in endolymph.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:10

    Topics: Animals; Cochlea; Dogs; Dose-Response Relationship, Drug; Ethacrynic Acid; Guinea Pigs; Hypoxia; Lab

1973
Factors influencing the electrical potential across the mucosa of rat colon.
    The Journal of physiology, 1968, Volume: 194, Issue:2

    Topics: Acetazolamide; Adrenalectomy; Animals; Biological Transport, Active; Blood Vessels; Chlorides; Chlor

1968