Page last updated: 2024-10-26

ethacrynic acid and Alkalosis

ethacrynic acid has been researched along with Alkalosis in 30 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Alkalosis: A pathological condition that removes acid or adds base to the body fluids.

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	30 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
CANNON, PJ	3
HEINEMANN, HO	3
STASON, WB	2
LARAGH, JH	3
BEYER, KH	1
BAER, JE	1
MICHAELSON, JK	1
RUSSO, HF	1
MAHER, JF	1
SCHREINER, GE	1
BERNSTEIN, A	1
ODZE, M	1
CREWS, A	1
SIMON, F	1
ALBERT, MS	1
WINTERS, RW	1
Magidson, O	1
de Sousa, RC	1
Jenny, M	1
James, JA	1
Langberg, H	1
Mathisen, O	1
Holdaas, H	1
Kiil, F	1
Veverbrants, E	1
Chazan, JA	1
Garella, S	1
Adrogué, HJ	1
Brensilver, J	1
Madias, NE	1
Laudignon, N	1
Ciampi, A	1
Coupal, L	1
Chemtob, S	1
Aranda, JV	1
Suzuki, Y	1
Ina, K	1
Yamada, H	1
Yamagami, I	1
Alguire, PC	1
Bailie, MD	1
Weaver, WJ	1
Taylor, DG	1
Hook, JB	1
Imler, M	1
Bockel, R	1
Peter, B	1
Kieny, R	1
Stahl, J	1
Riecker, G	1
Iff, HW	1
Flenley, DC	1
Sullivan, RC	1
Freemon, FR	1
Caranasos, GJ	1
Fort, AT	1
Morrison, JC	1
Fish, SA	1
Sherlock, S	1
Walker, JG	1
Senewiratne, B	1
Scott, A	1
Schmidt, P	1
Friedman, IS	1
Lieberman, FL	1
Reynolds, TB	1
Ardaillou, R	1
Fillastre, JP	1
Cohen, JJ	1
DeRubertis, FR	1
Michelis, MF	1
Beck, N	1
Davis, BB	1
Gross, W	1
Orlich, K	1
Olesen, KH	1
Brunner, FP	1
Andrieu, J	1
Lesueur, G	1

Trials

6 trials available for ethacrynic acid and Alkalosis

Article	Year
Extrarenal effects of diuretic agents. Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 4, Issue:1 Topics: Acidosis, Renal Tubular; Adipose Tissue; Alkalosis; Animals; Antihypertensive Agents; Blood Volume;	1970
The ventilatory response to CO 2 after administration of frusemide in normal man. Clinical science, 1972, Volume: 43, Issue:1 Topics: Acetazolamide; Administration, Oral; Adult; Alkalosis; Arteries; Bicarbonates; Blood Gas Analysis; C	1972
The use of ethacrynic acid in patients with cirrhosis and ascites. Gastroenterology, 1965, Volume: 49, Issue:5 Topics: Alkalosis; Ascites; Clinical Trials as Topic; Ethacrynic Acid; Humans; Hypokalemia; Liver Cirrhosis	1965
Physiologic and clincical observations on furosemide and ethacrynic acid. Annals of the New York Academy of Sciences, 1966, Nov-22, Volume: 139, Issue:2 Topics: Acid-Base Equilibrium; Alkalosis; Chlorides; Clinical Trials as Topic; Diuresis; Edema; Ethacrynic A	1966
Proximal tubular acidification in man. Clinical science, 1969, Volume: 37, Issue:3 Topics: Acidosis, Renal Tubular; Adult; Alkalosis; Ammonium Chloride; Bicarbonates; Chlorides; Chlorothiazid	1969
A comparison of the diuretic action of mercaptomerin, ethacrynic acid and furosemide in congestive heart failure. Acta medica Scandinavica, 1970, Volume: 187, Issue:5 Topics: Adult; Alkalosis; Ethacrynic Acid; Furosemide; Heart Failure; Humans; Organomercury Compounds; Potas	1970

Other Studies

24 other studies available for ethacrynic acid and Alkalosis

Article	Year
ETHACRYNIC ACID: EFFECTIVENESS AND MODE OF DIURETIC ACTION IN MAN. Circulation, 1965, Volume: 31 Topics: Acetazolamide; Acidosis; Acidosis, Renal Tubular; Alkalosis; Ascites; Carbonic Anhydrase Inhibitors;	1965
RENOTROPIC CHARACTERISTICS OF ETHACRYNIC ACID: A PHENOXYACETIC SALURETIC-DIURETIC AGENT. The Journal of pharmacology and experimental therapeutics, 1965, Volume: 147 Topics: Acidosis; Alkalosis; Chlorothiazide; Creatine; Creatinine; Diuretics; Dogs; Ethacrynic Acid; Hydroch	1965
STUDIES ON ETHACRYNIC ACID IN PATIENTS WITH REFRACTORY EDEMA. Annals of internal medicine, 1965, Volume: 62 Topics: Alkalosis; Blood; Chlorides; Creatine; Creatinine; Diuretics; Drug Therapy; Edema; Ethacrynic Acid;	1965
ETHACRYNIC ACID: A NEW POTENT DIURETIC. The American journal of the medical sciences, 1965, Volume: 249 Topics: Alkalosis; Blood Chemical Analysis; Blood Urea Nitrogen; Body Weight; Digitalis Glycosides; Diuresis	1965
"CONTRACTION" ALKALOSIS AFTER DIURESIS OF EDEMATOUS PATIENTS WITH ETHACRYNIC ACID. Annals of internal medicine, 1965, Volume: 62 Topics: Acid-Base Equilibrium; Alkalosis; Bicarbonates; Blood; Body Fluids; Body Weight; Chlorides; Diuresis	1965
Refractory heart failure. Geriatrics, 1967, Volume: 22, Issue:5 Topics: Adult; Aged; Alkalosis; Digitalis Glycosides; Diuretics; Ethacrynic Acid; Furosemide; Heart Failure;	1967
Clinical study of a new diuretic--ethacrynic acid. Helvetica medica acta, 1967, Volume: 33, Issue:5 Topics: Alkalosis; Ascites; Blood; Body Weight; Chlorides; Edema; Ethacrynic Acid; Heart Failure; Humans; Li	1967
Ethacrynic acid in edematous states in children. The Journal of pediatrics, 1967, Volume: 71, Issue:6 Topics: Alkalosis; Bicarbonates; Body Weight; Child; Child, Preschool; Chlorides; Ethacrynic Acid; Glomerulo	1967
Filtered bicarbonate and plasma pH as determinants of renal bicarbonate reabsorption. Kidney international, 1981, Volume: 20, Issue:6 Topics: Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Carbon Dioxide; Creatinine; Dogs; Ethacryn	1981
Ammonium excretion in response to acid loads: effect of metabolic alkalosis and cation depletion. The Journal of laboratory and clinical medicine, 1977, Volume: 89, Issue:6 Topics: Acidosis; Alkalosis; Ammonia; Animals; Bicarbonates; Chlorides; Dogs; Electrolytes; Ethacrynic Acid;	1977
Changes in the plasma anion gap during chronic metabolic acid-base disturbances. The American journal of physiology, 1978, Volume: 235, Issue:4 Topics: Acidosis; Alkalosis; Animals; Blood; Blood Proteins; Chlorides; Dogs; Ethacrynic Acid; Extracellular	1978
Furosemide and ethacrynic acid: risk factors for the occurrence of serum electrolyte abnormalities and metabolic alkalosis in newborns and infants. Acta paediatrica Scandinavica, 1989, Volume: 78, Issue:1 Topics: Acid-Base Equilibrium; Alkalosis; Electrolytes; Ethacrynic Acid; Furosemide; Humans; Infant; Infant,	1989
[Pharmacological studies on diuretics. 7. Diuretic activity and mechanism of action of a new thiazide diuretic, penfluzide]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:5 Topics: Adenosine Triphosphatases; Alkalosis; Animals; Antihypertensive Agents; Bendroflumethiazide; Blood P	1973
Differential effects of furosemide and ethacrynic acid on electrolyte excretion in anesthetized dogs. The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:3 Topics: Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Animals; Bicarbonates; Chlorides; Dogs; Et	1974
[Importance of hyperammoniemia of the renal origin in the pathogenesis of hepatic coma released in cirrhotic patients by diuretics generating hypokaliemia]. Pathologie-biologie, 1969, Volume: 17, Issue:1 Topics: Acetazolamide; Acid-Base Equilibrium; Alkalosis; Ammonia; Ascites; Chlorides; Chlorthalidone; Edema;	1969
Complications from diuretic therapy with ethacrynic acid and furosemide. Southern medical journal, 1971, Volume: 64, Issue:7 Topics: Adult; Alkalosis; Blood Volume; Ethacrynic Acid; Female; Furosemide; Humans; Hypokalemia; Hyponatrem	1971
Iatrogenic hypokalemia of pregnancy by furosemide and ethacrynic acid. The Journal of reproductive medicine, 1971, Volume: 6, Issue:5 Topics: Adolescent; Adult; Alkalosis; Ethacrynic Acid; Female; Furosemide; Hearing Disorders; Humans; Hypoka	1971
The complications of diuretic therapy in patients with cirrhosis. Annals of the New York Academy of Sciences, 1966, Nov-22, Volume: 139, Issue:2 Topics: Alkalosis; Ascites; Blood Urea Nitrogen; Chlorothiazide; Ethacrynic Acid; Furosemide; Hepatic Enceph	1966
Adverse effects of ethacrynic acid. New York state journal of medicine, 1967, Jun-01, Volume: 67, Issue:11 Topics: Aged; Alkalosis; Ethacrynic Acid; Heart Failure; Humans; Male; Middle Aged; Pancreatitis; Tachycardi	1967
Selective Cl retention in repair of metabolic alkalosis without increasing filtered load. The American journal of physiology, 1970, Volume: 218, Issue:1 Topics: Acid-Base Equilibrium; Alkalosis; Animals; Bicarbonates; Chlorides; Dogs; Ethacrynic Acid; Female; G	1970
Complications of diuretic therapy: severe alkalosis and syndrome resembling inappropriate secretion of antidiuretic hormone. Metabolism: clinical and experimental, 1970, Volume: 19, Issue:9 Topics: Alkalosis; Bicarbonates; Blood Pressure; Blood Urea Nitrogen; Diet, Sodium-Restricted; Diuresis; Ede	1970
[Changes in the acid-base equilibrium under the effect of different diuretics]. Klinische Wochenschrift, 1970, Mar-01, Volume: 48, Issue:5 Topics: Acid-Base Equilibrium; Alkalosis; Bicarbonates; Carbon Dioxide; Diuretics; Ethacrynic Acid; Furosemi	1970
[Clinical experiences with the new potassium sparing diuretic amilorid (Moduretic, Colectril, MK-870)]. Schweizerische medizinische Wochenschrift, 1967, Nov-18, Volume: 97, Issue:46 Topics: Aldosterone; Alkalosis; Diabetes Mellitus; Diuretics; Ethacrynic Acid; Heart Failure; Humans; Potass	1967
[Diuretics in cirrhosis. Accidents. Indications]. La Presse medicale, 1969, Mar-29, Volume: 77, Issue:16 Topics: Adrenal Cortex Hormones; Alkalosis; Blood Urea Nitrogen; Blood Volume; Diuretics; Edema; Ethacrynic	1969