ethacrynic acid has been researched along with Affective Psychosis, Bipolar in 5 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huff, MO | 2 |
| Li, XP | 1 |
| Ginns, E | 1 |
| El-Mallakh, RS | 3 |
| Valdes, RM | 1 |
| El-Masri, MA | 1 |
| Li, R | 1 |
| Naylor, GJ | 1 |
| Smith, AH | 1 |
| Antia, IJ | 1 |
| Smith, CE | 1 |
| Wood, AJ | 1 |
| Aronson, JK | 1 |
5 other studies available for ethacrynic acid and Affective Psychosis, Bipolar
| Article | Year |
|---|---|
Effect of ethacrynic acid on the sodium- and potassium-activated adenosine triphosphatase activity and expression in Old Order Amish bipolar individuals.
Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Blotting, Western; Cell Line; Enzyme Inhibitors; E | 2010 |
Effect of ethacrynic acid on sodium pump alpha isoforms in SH-SY5Y cells.
Topics: Bipolar Disorder; Blotting, Western; Brain Neoplasms; Diuretics; Ethacrynic Acid; Humans; Immunoblot | 2003 |
Differential response of bipolar and normal control lymphoblastoid cell sodium pump to ethacrynic acid.
Topics: Adult; Bipolar Disorder; Blotting, Western; Cell Line; Ethacrynic Acid; Female; Humans; Lymphocytes; | 2004 |
Defective genetic control of sodium-pump density in manic depressive psychosis.
Topics: Bipolar Disorder; Cell Membrane Permeability; Erythrocytes; Ethacrynic Acid; Female; Humans; In Vitr | 1981 |
The upregulation of Na+,K(+)-ATPase pump numbers in lymphocytes from the first-degree unaffected relatives of patients with manic depressive psychosis in response to in vitro lithium and sodium ethacrynate.
Topics: Bipolar Disorder; Cells, Cultured; Ethacrynic Acid; Humans; Lithium Chloride; Lymphocytes; Sodium-Po | 1995 |