Page last updated: 2024-10-26

ethacrynic acid and Adenocarcinoma, Basal Cell

ethacrynic acid has been researched along with Adenocarcinoma, Basal Cell in 4 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Research Excerpts

ExcerptRelevanceReference
" Since GST inhibitors such as ethacrynic acid are suggested to induce apoptosis in some cell lines, the effect of benastatin A on the survival of mouse colon 26 adenocarcinoma cells was compared with that of ethacrynic acid."3.70Induction of apoptosis and cell cycle arrest in mouse colon 26 cells by benastatin A. ( Aoyagi, T; Hayakari, M; Ishikawa, T; Kakizaki, I; Ookawa, K; Tsuchida, S, 2000)
" Addition of ethacrynic acid (3 micrograms ml-1) to treatment of the cell lines with melphalan or with cisplatin did not alter the dose-response curves to these agents."1.28A study of ethacrynic acid as a potential modifier of melphalan and cisplatin sensitivity in human lung cancer parental and drug-resistant cell lines. ( Rhodes, T; Twentyman, PR, 1992)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chung, FH1
Chiang, YR1
Tseng, AL1
Sung, YC1
Lu, J1
Huang, MC1
Ma, N1
Lee, HC1
Kakizaki, I1
Ookawa, K1
Ishikawa, T1
Hayakari, M1
Aoyagi, T1
Tsuchida, S1
Rhodes, T1
Twentyman, PR1
Murphy, GP1
Mirand, EA1
Johnston, GS1
Gibbons, RP1
Schirmer, HK1
Scott, WW1

Other Studies

4 other studies available for ethacrynic acid and Adenocarcinoma, Basal Cell

ArticleYear
Functional Module Connectivity Map (FMCM): a framework for searching repurposed drug compounds for systems treatment of cancer and an application to colorectal adenocarcinoma.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Adenocarcinoma; Algorithms; Colorectal Neoplasms; Drug Repositioning; Epistasis, Genetic; Ethacrynic

2014
Induction of apoptosis and cell cycle arrest in mouse colon 26 cells by benastatin A.
    Japanese journal of cancer research : Gann, 2000, Volume: 91, Issue:11

    Topics: Adenocarcinoma; Animals; Apoptosis; Benz(a)Anthracenes; Cell Cycle; Cell Survival; Colonic Neoplasms

2000
A study of ethacrynic acid as a potential modifier of melphalan and cisplatin sensitivity in human lung cancer parental and drug-resistant cell lines.
    British journal of cancer, 1992, Volume: 65, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Dr

1992
Erythropoietin alterations in human genitourinary disease states: correlation with experimental observations.
    The Journal of urology, 1968, Volume: 99, Issue:6

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Animals; Brain Neoplasms; Child; Child, Preschool; Dogs; El

1968