ethacrynic acid has been researched along with Acute Kidney Tubular Necrosis in 3 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The combined venodilatory and natriuretic effects of bumetanide, furosemide and ethacrynic acid relieve congestive symptoms in pulmonary edema." | 4.77 | Diuretic use in critical care. ( Chusid, P; Narins, RG, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nierenberg, DW | 1 |
| Steiner, RW | 1 |
| Blantz, RC | 1 |
| Narins, RG | 1 |
| Chusid, P | 1 |
1 review available for ethacrynic acid and Acute Kidney Tubular Necrosis
| Article | Year |
|---|---|
Diuretic use in critical care.
Topics: Biological Transport; Calcium; Critical Care; Diuretics; Ethacrynic Acid; Extracellular Space; Human | 1986 |
2 other studies available for ethacrynic acid and Acute Kidney Tubular Necrosis
| Article | Year |
|---|---|
Furosemide and ethacrynic acid in acute tubular necrosis.
Topics: Acute Kidney Injury; Adult; Ethacrynic Acid; Female; Furosemide; Humans; Kidney Tubular Necrosis, Ac | 1980 |
The use of diuretics in nonedematous conditions.
Topics: Acute Kidney Injury; Benzothiadiazines; Calcium; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hyp | 1979 |