ethacrynic acid has been researched along with Acute Kidney Injury in 43 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of diuretics during acute renal failure in animals has been demonstrated to be of value with mannitol and/or loop-blocking diuretics, furosemide or ethacrynic acid." | 1.27 | The use of diuretics in varying degrees of renal impairment: an overview. ( Dickerman, D; Lowenthal, DT, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lowenthal, DT | 1 |
| Dickerman, D | 1 |
| Priebe, HJ | 1 |
| de Rougemont, D | 1 |
| Wunderlich, PF | 1 |
| Torhorst, J | 1 |
| Keller, M | 1 |
| Peters-Häfeli, L | 1 |
| Thiel, G | 1 |
| Brunner, FP | 1 |
| Fink, M | 1 |
| Nierenberg, DW | 1 |
| Gordillo-Paniagua, G | 1 |
| Velasquez-Jones, L | 1 |
| Steiner, RW | 1 |
| Blantz, RC | 1 |
| Davies, DL | 1 |
| Wilson, GM | 1 |
| Beauchamp, GD | 1 |
| Crouch, TC | 1 |
| Clausen, G | 1 |
| Nagy, Z | 1 |
| Szalay, L | 1 |
| Aukland, K | 1 |
| Krumlovsky, FA | 1 |
| del Greco, F | 1 |
| Gilson, SB | 1 |
| Kaye, M | 1 |
| Dufresne, L | 1 |
| McDade, D | 1 |
| Ng, PS | 1 |
| Conley, CE | 1 |
| Ing, TS | 1 |
| Barac, G | 1 |
| Gobin, R | 1 |
| Takasu, T | 1 |
| Frazier, HS | 1 |
| Yager, H | 1 |
| Kawaguchi, Y | 1 |
| Sakai, S | 1 |
| Yamamoto, M | 1 |
| Tanaka, S | 1 |
| Oda, Y | 1 |
| Kjellstrand, CM | 1 |
| Underwood, F | 1 |
| Bennett, WM | 1 |
| Powell, HC | 1 |
| Garret, RS | 1 |
| Bernstein, L | 1 |
| Mazze, RI | 1 |
| MacLennan, WJ | 1 |
| Levin, NW | 1 |
| Le Gall, JR | 1 |
| Gajdos, P | 1 |
| Eng, K | 1 |
| Stahl, WM | 3 |
| Stone, AM | 2 |
| Handa, SP | 1 |
| Lemieux, G | 1 |
| Talbot, P | 1 |
| Laurent, G | 1 |
| Gilson, S | 1 |
| Eng, B | 1 |
| Dodds, MG | 1 |
| Foord, RD | 1 |
| Chinitz, JL | 1 |
| Kim, KE | 1 |
| Onesti, G | 1 |
| Swartz, C | 1 |
| Krecke, HJ | 1 |
| Klein, H | 1 |
| Uhse, HG | 1 |
| Krück, F | 1 |
| Schroder, K | 1 |
| Gessler, U | 1 |
| Auger, RG | 1 |
| Dayton, DA | 1 |
| Harrison, CE | 1 |
| Tucker, RM | 1 |
| Anderson, CF | 1 |
| Mathog, RH | 1 |
| Klein, WJ | 1 |
| Quellhorst, E | 1 |
| Scheler, F | 1 |
| Matz, GJ | 1 |
| Beal, DD | 1 |
| Krames, L | 1 |
| Bartlett, RH | 1 |
| Yahia, C | 1 |
| Lieberman, FL | 1 |
| Reynolds, TB | 1 |
8 reviews available for ethacrynic acid and Acute Kidney Injury
| Article | Year |
|---|---|
Diuretics.
Topics: Acetazolamide; Acute Kidney Injury; Chlorothiazide; Diuretics; Diuretics, Osmotic; Ethacrynic Acid; | 1984 |
Are diuretics useful in the treatment or prevention of acute renal failure?
Topics: Acute Kidney Injury; Animals; Diuretics; Dogs; Ethacrynic Acid; Furosemide; Humans; Mannitol; Models | 1982 |
Acute renal failure.
Topics: Acute Kidney Injury; Blood Urea Nitrogen; Dehydration; Diarrhea, Infantile; Ethacrynic Acid; Furosem | 1976 |
Diuretics: mechanism of action and clinical application.
Topics: Acute Kidney Injury; Amiloride; Animals; Benzothiadiazines; Diabetes Insipidus; Diuretics; Diuretics | 1975 |
The clinical use of diuretics. 2.
Topics: Acute Kidney Injury; Diabetes Insipidus; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hypertensio | 1973 |
[Effects of potent diuretics in renal failure].
Topics: Acute Kidney Injury; Benzoates; Butylamines; Diuresis; Diuretics; Dose-Response Relationship, Drug; | 1974 |
Furosemide and ethacrynic acid in renal insufficiency.
Topics: Acute Kidney Injury; Adult; Animals; Dogs; Ethacrynic Acid; Furosemide; Humans; Kidney; Kidney Failu | 1971 |
[Present data on the physiopathology of acute kidney tubule diseases].
Topics: Acute Disease; Acute Kidney Injury; Animals; Dogs; Ethacrynic Acid; Glomerular Filtration Rate; Hemo | 1971 |
35 other studies available for ethacrynic acid and Acute Kidney Injury
| Article | Year |
|---|---|
The use of diuretics in varying degrees of renal impairment: an overview.
Topics: Acute Kidney Injury; Bumetanide; Diuretics; Ethacrynic Acid; Furosemide; Humans; Kidney Failure, Chr | 1983 |
Hgcl2-induced acute renal failure in the rat. Effect of water diuresis, saline loading, and diuretic drugs.
Topics: Acute Kidney Injury; Animals; Desoxycorticosterone; Diuresis; Diuretics; Ethacrynic Acid; Female; Fu | 1982 |
Furosemide and ethacrynic acid in acute tubular necrosis.
Topics: Acute Kidney Injury; Adult; Ethacrynic Acid; Female; Furosemide; Humans; Kidney Tubular Necrosis, Ac | 1980 |
The use of diuretics in nonedematous conditions.
Topics: Acute Kidney Injury; Benzothiadiazines; Calcium; Diuretics; Ethacrynic Acid; Furosemide; Humans; Hyp | 1979 |
Deafness. Review of intravenous ethacrynic acid.
Topics: Acute Kidney Injury; Aminoglycosides; Deafness; Drug Therapy, Combination; Ethacrynic Acid; Humans; | 1975 |
Mechanisms in acute oliguric renal failure induced by tetracycline infusion.
Topics: Acute Kidney Injury; Animals; Anuria; Blood Pressure; Dogs; Ethacrynic Acid; Glomerular Filtration R | 1975 |
Diuretic agents. Mechanisms of action and clinical uses.
Topics: Acute Kidney Injury; Benzothiadiazines; Carbonic Anhydrase Inhibitors; Diabetes Insipidus; Diuretics | 1976 |
Letter: Glycerol and intracranial surgery.
Topics: Acute Kidney Injury; Animals; Diuresis; Ethacrynic Acid; Glycerol; Kidney; Neurosurgery; Postoperati | 1974 |
Ethacrynic acid in acute renal failure.
Topics: Acute Kidney Injury; Aged; Ethacrynic Acid; Female; Humans | 1968 |
Deafness after ethacrynic acid.
Topics: Acute Kidney Injury; Adult; Deafness; Ethacrynic Acid; Female; Humans | 1969 |
[Diuretic effect of ethacrynic acid in acute oliguria caused by burns].
Topics: Acute Kidney Injury; Animals; Anuria; Burns; Diuresis; Dogs; Ethacrynic Acid | 1969 |
[My prescription of diuretics].
Topics: Acute Kidney Injury; Benzothiadiazines; Diuretics; Edema; Ethacrynic Acid; Furosemide; Humans; Hyper | 1974 |
Ethacrynic acid in acute tubular necrosis. Indications and effect on the natural course.
Topics: Acute Kidney Injury; Aged; Child, Preschool; Ethacrynic Acid; Hearing Disorders; Humans; Kidney; Mid | 1972 |
Ethylene glycol intoxication. Prevention of renal failure by aggressive management.
Topics: Acute Kidney Injury; Adult; Bicarbonates; Ethacrynic Acid; Ethanol; Ethylenes; Glycols; Hematuria; H | 1973 |
Methoxyflurane nephropathy.
Topics: Acute Kidney Injury; Aged; Anesthesia, Inhalation; Anuria; Calcinosis; Endoplasmic Reticulum; Ethacr | 1974 |
Drug interactions.
Topics: 1-Propanol; Acute Kidney Injury; Aged; Albumins; Antidepressive Agents; Antihypertensive Agents; Ben | 1974 |
[Current physiopathological data on the precocious treatment of acute tubular diseases by furosemide or high doses of ethacrynic acid].
Topics: Acute Kidney Injury; Ethacrynic Acid; Furosemide; Ischemia; Kidney; Kidney Cortex Necrosis; Kidney G | 1972 |
Correction of the renal hemodynamic changes produced by surgical trauma.
Topics: Acute Kidney Injury; Animals; Blood Flow Velocity; Dogs; Ethacrynic Acid; Extracorporeal Circulation | 1971 |
Effect of ethacrynic acid and furosemide on renal function in hypovolemia.
Topics: Acute Kidney Injury; Adult; Animals; Blood Pressure; Cardiac Output; Diuresis; Dogs; Ethacrynic Acid | 1971 |
[High doses of diuretics in renal insufficiency].
Topics: Acute Kidney Injury; Diuretics; Ethacrynic Acid; Furosemide; Humans; Injections, Intravenous; Kidney | 1971 |
[High doses of diuretics in renal insufficiency].
Topics: Acute Kidney Injury; Diuretics; Ethacrynic Acid; Furosemide; Humans; Injections, Intravenous; Kidney | 1971 |
Acute renal railure in association with hyperuricemia: its recovery with ethacrynic acid.
Topics: Acute Kidney Injury; Bicarbonates; Ethacrynic Acid; Female; Humans; Infusions, Parenteral; Leukemia, | 1971 |
[Use of ethacrynic acid for acute renal failure].
Topics: Acute Kidney Injury; Adult; Age Factors; Aged; Anuria; Ethacrynic Acid; Female; Gastrointestinal Hem | 1971 |
Renal medullary hypertonicity and the pathogenesis of acute renal failure.
Topics: Acute Kidney Injury; Animals; Diuresis; Ethacrynic Acid; Kidney Concentrating Ability; Kidney Diseas | 1969 |
Prophylactic diuresis with ethacrynic acid for prevention of postoperative renal failure.
Topics: Abdomen; Acute Kidney Injury; Cardiac Surgical Procedures; Ethacrynic Acid; Glomerular Filtration Ra | 1970 |
Enhancement by potent diuretics of renal tubular necrosis induced by cephaloridine.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cephaloridine; Creatinine; Drug Synergism; Ethacr | 1970 |
Pathophysiology and prevention of dextran-40-induced anuria.
Topics: Acute Kidney Injury; Animals; Anuria; Dextrans; Disease Models, Animal; Dogs; Ethacrynic Acid; Hypot | 1971 |
[Renal hemodynamics, electrolyte excretion and acid-base equilibrium in an acute human experiment with ethacrynic acid].
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Adolescent; Adult; Aged; Aminohippuric Acids; Ethacrynic | 1971 |
The influence of mannitol, ethacrynic acid and frusemide on glomerular filtration in experimental acute renal failure.
Topics: Acute Kidney Injury; Animals; Anuria; Blood Pressure; Diuresis; Ethacrynic Acid; Furosemide; Glomeru | 1971 |
Use of ethacrynic acid in mannitol-resistant oliguric renal failure.
Topics: Acute Kidney Injury; Adult; Anuria; Diuresis; Drug Synergism; Ethacrynic Acid; Female; Humans; Injec | 1968 |
Ototoxicity of ethacrynic acid and aminoglycoside antibiotics in uremia.
Topics: Acute Kidney Injury; Adult; Amino Sugars; Anti-Bacterial Agents; Audiometry; Deafness; Ethacrynic Ac | 1969 |
[On the management of renal acidosis using sodium bicarbonate and ethacrynic acid].
Topics: Acidosis, Renal Tubular; Acute Kidney Injury; Adult; Bicarbonates; Blood Pressure; Body Weight; Etha | 1969 |
Ototoxicity of ethacrynic acid. Demonstrated in a human temporal bone.
Topics: Acute Kidney Injury; Deafness; Ear, Inner; Ear, Middle; Ethacrynic Acid; Female; Humans; Liver Cirrh | 1969 |
Management of septic chemical abortion with renal failure. Report of five consecutive cases with five survivors.
Topics: Abortion, Criminal; Abortion, Septic; Acute Kidney Injury; Adult; Carbon Dioxide; Ethacrynic Acid; F | 1969 |
Renal failure with cirrhosis. Observations on the role of diuretics.
Topics: Acute Kidney Injury; Aminohippuric Acids; Ascites; Blood; Blood Volume; Creatine; Diuretics; Ethacry | 1966 |