ethacrynic acid has been researched along with Acute Disease in 15 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dose-response curves (s." | 1.32 | Interaction between metamizol and tramadol in a model of acute visceral pain in rats. ( Planas, E; Pol, O; Poveda, R; Puig, MM; Romero, A; Sánchez, S, 2003) |
| "Gentamicin sulfate was given as a single injection (100 mg/kg of body weight subcutaneously), followed 90 minutes later by varying concentrations of ethacrynic acid intravenously." | 1.29 | A sensitive animal model to assess acute and chronic ototoxic effects. ( Lautermann, J; Schacht, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nagy, T | 1 |
| Kovács, V | 1 |
| Hardi, P | 1 |
| Veres, TG | 1 |
| Takács, I | 1 |
| Jancsó, G | 1 |
| Sinay, L | 1 |
| Fazekas, G | 1 |
| Pintér, Ö | 1 |
| Arató, E | 1 |
| Poveda, R | 1 |
| Planas, E | 1 |
| Pol, O | 1 |
| Romero, A | 1 |
| Sánchez, S | 1 |
| Puig, MM | 1 |
| Lewy, JE | 1 |
| Lautermann, J | 1 |
| Schacht, J | 1 |
| Swartz, C | 1 |
| Kim, KE | 1 |
| Larochelle, P | 1 |
| Ogilvie, RI | 1 |
| Schenk, KE | 1 |
| Biamino, G | 1 |
| Schröder, R | 1 |
| Aladzhova, D | 1 |
| Tsareva, M | 1 |
| Kostova, R | 1 |
| Rybak, LP | 1 |
| Whitworth, C | 1 |
| Scott, V | 1 |
| Holzgreve, H | 1 |
| Le Gall, JR | 1 |
| Schmidt, P | 1 |
| Filipecki, S | 1 |
| Chodakowska, J | 1 |
| Bar-Andziak, E | 1 |
| Scheinman, M | 1 |
| Brown, M | 1 |
| Rapaport, E | 1 |
| Lesch, M | 1 |
| Caranasos, GJ | 1 |
| Mulholland, JH | 1 |
2 reviews available for ethacrynic acid and Acute Disease
| Article | Year |
|---|---|
Diuretics in infancy.
Topics: Acute Disease; Benzothiadiazines; Diet, Sodium-Restricted; Diuretics; Diuretics, Osmotic; Edema; Eth | 1981 |
[Present data on the physiopathology of acute kidney tubule diseases].
Topics: Acute Disease; Acute Kidney Injury; Animals; Dogs; Ethacrynic Acid; Glomerular Filtration Rate; Hemo | 1971 |
2 trials available for ethacrynic acid and Acute Disease
| Article | Year |
|---|---|
[Haemodynamic effects of furosemide and ethacrynic acid (author's transl)].
Topics: Acute Disease; Blood Pressure; Blood Vessels; Coronary Disease; Ethacrynic Acid; Furosemide; Heart; | 1975 |
Controlled study comparing ethacrynic acid to mercaptomerin in the treatment of acute pulmonary edema.
Topics: Acute Disease; Adult; Aged; Creatinine; Diuresis; Ethacrynic Acid; Female; Heart Diseases; Humans; I | 1968 |
11 other studies available for ethacrynic acid and Acute Disease
| Article | Year |
|---|---|
Inhibition of Glutathione S-Transferase by Ethacrynic Acid Augments Ischemia-Reperfusion Damage and Apoptosis and Attenuates the Positive Effect of Ischemic Postconditioning in a Bilateral Acute Hindlimb Ischemia Rat Model.
Topics: Acute Disease; Animals; Apoptosis; Ethacrynic Acid; Glutathione; Glutathione Transferase; Hindlimb; | 2015 |
Interaction between metamizol and tramadol in a model of acute visceral pain in rats.
Topics: Abdominal Pain; Acute Disease; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 2003 |
A sensitive animal model to assess acute and chronic ototoxic effects.
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Auditory Threshold; Diet, Protein-Restricted; Disease | 1996 |
Treatment of complicated hypertension.
Topics: Acute Disease; Cerebral Hemorrhage; Cerebrovascular Disorders; Chronic Disease; Coronary Disease; Di | 1977 |
Effect of drugs on effective vascular compliance in acute heart failure.
Topics: Acute Disease; Animals; Aorta, Thoracic; Coronary Vessels; Dogs; Ethacrynic Acid; Heart Failure; Mal | 1975 |
[Use of diuretics in pulmonary edema in children with peritonitis of appendicular origin].
Topics: Acute Disease; Adolescent; Appendicitis; Child; Child, Preschool; Diuretics; Ethacrynic Acid; Female | 1975 |
Comparative acute ototoxicity of loop diuretic compounds.
Topics: Acute Disease; Animals; Bumetanide; Chinchilla; Cochlea; Diuretics; Dose-Response Relationship, Drug | 1991 |
[Diuretics in acute glomerulonephritis?].
Topics: Acute Disease; Diuretics; Ethacrynic Acid; Furosemide; Glomerulonephritis; Humans; Kidney Diseases; | 1973 |
[Diuresis and diuretics].
Topics: Acetazolamide; Acute Disease; Agranulocytosis; Anuria; Biological Transport; Blood Platelet Disorder | 1971 |
[Results of treatment with intravenous ethacrynic acid injections of patients with acute left ventricular circulatory failure].
Topics: Acute Disease; Adult; Aged; Arteriosclerosis; Diuresis; Ethacrynic Acid; Female; Heart Defects, Cong | 1971 |
Hemodynamic effect of ethacrynic acid in patients with refractory acute left ventricular failure.
Topics: Acute Disease; Blood Pressure; Carbon Dioxide; Cardiac Output; Coronary Care Units; Ethacrynic Acid; | 1971 |