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ethacrynic acid and Acute Brain Injuries

ethacrynic acid has been researched along with Acute Brain Injuries in 3 studies

Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cragoe, EJ1
Gould, NP1
Woltersdorf, OW1
Ziegler, C1
Bourke, RS1
Nelson, LR1
Kimelberg, HK1
Waldman, JB1
Popp, AJ1
Sedransk, N1
Sasaki, M1
Manaka, S1
Takakura, K1
Baethmann, A1
Lanksch, W1
Schmiedek, P1

Other Studies

3 other studies available for ethacrynic acid and Acute Brain Injuries

ArticleYear
Agents for the treatment of brain injury. 1. (Aryloxy)alkanoic acids.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:5

    Topics: Animals; Astrocytes; Bicarbonates; Brain Injuries; Carboxylic Acids; Cats; Cerebral Cortex; Chemical

1982
[Protective effect on the brain of ion-blockers in experimental head injury].
    No shinkei geka. Neurological surgery, 1987, Volume: 15, Issue:2

    Topics: Animals; Brain Injuries; Consciousness Disorders; Ethacrynic Acid; Flunarizine; Ion Channels; Male;

1987
Formation and treatment of cerebral edema.
    Neurochirurgia, 1974, Volume: 17, Issue:2

    Topics: Aldosterone; Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Dexamethasone; Ethacrynic Ac

1974