ethacrynic acid has been researched along with Acidosis, Renal Tubular in 13 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
Acidosis, Renal Tubular: A group of genetic disorders of the KIDNEY TUBULES characterized by the accumulation of metabolically produced acids with elevated plasma chloride, hyperchloremic metabolic ACIDOSIS. Defective renal acidification of URINE (proximal tubules) or low renal acid excretion (distal tubules) can lead to complications such as HYPOKALEMIA, hypercalcinuria with NEPHROLITHIASIS and NEPHROCALCINOSIS, and RICKETS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 cirrhotic patients with latent distal renal tubular acidosis (RTA) and 5 cirrhotic patients with normal distal acidification ability were studied." | 1.27 | Pathogenetic relationships between renal tubular acidosis and sodium metabolism alterations in liver cirrhosis. ( Caregaro, L; Gatta, A; Lauro, S; Ricci, G; Ruol, A; Zuin, R, 1983) |
| "The fundamental disorder in renal tubular acidosis--the impaired excretions of hydrogen ions--can favourably be influenced by etacrynic acid (Hydromedin)." | 1.26 | Renal tubular acidosis: effects of etacrynic acid on renal acid and calcium excretion. ( Riehle, M; Sommerkamp, H, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CANNON, PJ | 2 |
| HEINEMANN, HO | 1 |
| STASON, WB | 1 |
| LARAGH, JH | 2 |
| Caregaro, L | 1 |
| Lauro, S | 1 |
| Ricci, G | 1 |
| Gatta, A | 1 |
| Zuin, R | 1 |
| Ruol, A | 1 |
| Sommerkamp, H | 1 |
| Riehle, M | 1 |
| Heidbreder, E | 2 |
| Hennemann, H | 2 |
| Heidland, A | 2 |
| Krempien, B | 2 |
| Radó, JP | 1 |
| Szabó, T | 1 |
| Szende, L | 1 |
| Takó, J | 1 |
| Dévényi, I | 1 |
| Hutás, I | 1 |
| Gartner, P | 1 |
| Gergely, R | 1 |
| Riecker, G | 1 |
| Györy, AZ | 1 |
| Edwards, KD | 1 |
| Ardaillou, R | 2 |
| Fillastre, JP | 2 |
| Quellhorst, E | 2 |
| Henning, HV | 1 |
| Mietzsch, G | 1 |
| Stegemann, I | 1 |
| Scheler, F | 2 |
| Ames, RP | 1 |
2 trials available for ethacrynic acid and Acidosis, Renal Tubular
| Article | Year |
|---|---|
Extrarenal effects of diuretic agents.
Topics: Acidosis, Renal Tubular; Adipose Tissue; Alkalosis; Animals; Antihypertensive Agents; Blood Volume; | 1970 |
Proximal tubular acidification in man.
Topics: Acidosis, Renal Tubular; Adult; Alkalosis; Ammonium Chloride; Bicarbonates; Chlorides; Chlorothiazid | 1969 |
11 other studies available for ethacrynic acid and Acidosis, Renal Tubular
| Article | Year |
|---|---|
ETHACRYNIC ACID: EFFECTIVENESS AND MODE OF DIURETIC ACTION IN MAN.
Topics: Acetazolamide; Acidosis; Acidosis, Renal Tubular; Alkalosis; Ascites; Carbonic Anhydrase Inhibitors; | 1965 |
Pathogenetic relationships between renal tubular acidosis and sodium metabolism alterations in liver cirrhosis.
Topics: Acidosis, Renal Tubular; Adult; Ethacrynic Acid; Female; Humans; Hydrogen-Ion Concentration; Kidney | 1983 |
Renal tubular acidosis: effects of etacrynic acid on renal acid and calcium excretion.
Topics: Acidosis, Renal Tubular; Adult; Calcium; Ethacrynic Acid; Female; Humans; Male; Middle Aged | 1982 |
Treatment of renal tubular acidosis and osteomalacia by salidiuretics.
Topics: Acidosis, Renal Tubular; Ethacrynic Acid; Humans; Male; Middle Aged; Osteomalacia | 1973 |
Excessive decrease in free water clearance induced by furosemide and ethacrynic acid in nephrogenic diabetes insipidus associated with renal tubular acidosis.
Topics: Acidosis, Renal Tubular; Adult; Chlorpropamide; Diabetes Insipidus; Ethacrynic Acid; Female; Furosem | 1973 |
[Salidiuretic therapy of renal tubular acidosis and its complications].
Topics: Acidosis, Renal Tubular; Bicarbonates; Biopsy; Blood Chemical Analysis; Blood Gas Analysis; Bone and | 1972 |
Effect of mersalyl, ethacrynic acid and sodium sulphate infusion on urinary acidification in hereditary renal tubular acidosis.
Topics: Acidosis, Renal Tubular; Diuretics; Ethacrynic Acid; Humans; Hydrogen-Ion Concentration; Organomercu | 1971 |
[Improvement of acidosis treatment in chronic kidney failure using ethacrynic acid].
Topics: Acidosis, Renal Tubular; Creatinine; Ethacrynic Acid; Humans; Kidney Failure, Chronic | 1968 |
[On the management of renal acidosis using sodium bicarbonate and ethacrynic acid].
Topics: Acidosis, Renal Tubular; Acute Kidney Injury; Adult; Bicarbonates; Blood Pressure; Body Weight; Etha | 1969 |
[Dilution urinary acidosis and urinary PCO2 after ethacrynic acid injection during an alkaline overload].
Topics: Acidosis, Renal Tubular; Ammonia; Bicarbonates; Carbon Dioxide; Ethacrynic Acid; Furosemide; Humans; | 1969 |
Relation between potassium balance and aldosterone secretion in normal subjects and in patients with hypertensive or renal tubular disease.
Topics: Acidosis, Renal Tubular; Adrenal Gland Neoplasms; Adult; Aldosterone; Ethacrynic Acid; Female; Human | 1966 |