ethacrynic acid has been researched along with Abnormality, Heart in 6 studies
Ethacrynic Acid: A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.
etacrynic acid : An aromatic ether that is phenoxyacetic acid in which the phenyl ring is substituted by chlorines at positions 2 and 3, and by a 2-methylidenebutanoyl group at position 4. It is a loop diuretic used to treat high blood pressure resulting from diseases such as congestive heart failure, liver failure, and kidney failure. It is also a glutathione S-transferase (EC 2.5.1.18) inhibitor.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ricci, Z | 1 |
| Haiberger, R | 1 |
| Pezzella, C | 1 |
| Garisto, C | 1 |
| Favia, I | 1 |
| Cogo, P | 1 |
| Goldring, D | 1 |
| Hernandez, A | 1 |
| Hartmann, AF | 1 |
| Viles, PH | 1 |
| Manning, JA | 1 |
| Filipecki, S | 1 |
| Chodakowska, J | 1 |
| Bar-Andziak, E | 1 |
| Soulié, P | 1 |
| Gaudeau, S | 1 |
| Degeorges, M | 1 |
| Samet, P | 1 |
| Bernstein, WH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase III Study of Furosemide Continuous Infusion Versus Ethacrynic Acid Continuous Infusion in Children Undergoing Cardiac Surgery: Randomized Double Blind Controlled Clinical Trial[NCT01628731] | Phase 3 | 74 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for ethacrynic acid and Abnormality, Heart
| Article | Year |
|---|---|
Recent advances in the treatment of congenital heart disease.
Topics: Age Factors; Arrhythmias, Cardiac; Child; Child, Preschool; Chlorothiazide; Diet, Sodium-Restricted; | 1974 |
1 trial available for ethacrynic acid and Abnormality, Heart
| Article | Year |
|---|---|
Furosemide versus ethacrynic acid in pediatric patients undergoing cardiac surgery: a randomized controlled trial.
Topics: Cardiac Surgical Procedures; Diuretics; Double-Blind Method; Ethacrynic Acid; Female; Furosemide; He | 2015 |
4 other studies available for ethacrynic acid and Abnormality, Heart
| Article | Year |
|---|---|
The critically ill child: care of the infant in cardiac failure.
Topics: Acidosis, Respiratory; Age Factors; Arrhythmias, Cardiac; Cardiac Catheterization; Cardiomegaly; Cya | 1971 |
[Results of treatment with intravenous ethacrynic acid injections of patients with acute left ventricular circulatory failure].
Topics: Acute Disease; Adult; Aged; Arteriosclerosis; Diuresis; Ethacrynic Acid; Female; Heart Defects, Cong | 1971 |
[Ethacrynic acid by the venous or oral route in the treatment of a cardiac insufficiency attack].
Topics: Administration, Oral; Adolescent; Adult; Aged; Ethacrynic Acid; Female; Heart Defects, Congenital; H | 1967 |
Acute effects of oral ethacrynic acid upon total blood volume.
Topics: Blood Volume; Ethacrynic Acid; Heart Defects, Congenital; Heart Failure; Humans; Plasma Volume; Pulm | 1968 |