etazolate has been researched along with Memory Disorders in 3 studies
Etazolate: A potent phosphodiesterase inhibitor proposed as an antipsychotic agent.
etazolate : A pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties.
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate etazolate against depression-like behavior and, learning and memory impairment induced by 6- hydroxydopamine (6-OHDA) rat model of Parkinson's disease (PD)." | 7.88 | Beneficial effect of etazolate on depression-like behavior and, learning, and memory impairment in a model of Parkinson's disease. ( Abuirmeileh, AN; Alzoubi, KH; Mokhemer, E, 2018) |
| "Etazolate is a selective phosphodiesterase-4 inhibitor that is specific for cAMP." | 5.46 | Evaluating the protective effect of etazolate on memory impairment, anxiety- and depression-like behaviors induced by post traumatic stress disorder. ( Al Subeh, ZY; Alzoubi, KH; Khabour, OF, 2017) |
| "The aim of this study was to evaluate etazolate against depression-like behavior and, learning and memory impairment induced by 6- hydroxydopamine (6-OHDA) rat model of Parkinson's disease (PD)." | 3.88 | Beneficial effect of etazolate on depression-like behavior and, learning, and memory impairment in a model of Parkinson's disease. ( Abuirmeileh, AN; Alzoubi, KH; Mokhemer, E, 2018) |
| "Etazolate treatment, on the other hand, led to prevention of changes in these oxidative stress biomarkers (GSH, GSSG, GPx and TBARS), BDNF levels, and histones acetylation." | 1.51 | Molecular targets for the interactive effect of etazolate during post-traumatic stress disorder: Role of oxidative stress, BDNF and histones. ( Al Subeh, ZY; Alzoubi, KH; Khabour, OF, 2019) |
| "Etazolate is a selective phosphodiesterase-4 inhibitor that is specific for cAMP." | 1.46 | Evaluating the protective effect of etazolate on memory impairment, anxiety- and depression-like behaviors induced by post traumatic stress disorder. ( Al Subeh, ZY; Alzoubi, KH; Khabour, OF, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alzoubi, KH | 3 |
| Al Subeh, ZY | 2 |
| Khabour, OF | 2 |
| Mokhemer, E | 1 |
| Abuirmeileh, AN | 1 |
3 other studies available for etazolate and Memory Disorders
| Article | Year |
|---|---|
Evaluating the protective effect of etazolate on memory impairment, anxiety- and depression-like behaviors induced by post traumatic stress disorder.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Animal; D | 2017 |
Beneficial effect of etazolate on depression-like behavior and, learning, and memory impairment in a model of Parkinson's disease.
Topics: Animals; Antiparkinson Agents; Depression; Etazolate; Hippocampus; Learning Disabilities; Male; Memo | 2018 |
Molecular targets for the interactive effect of etazolate during post-traumatic stress disorder: Role of oxidative stress, BDNF and histones.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Animal; B | 2019 |