etazolate has been researched along with Brain Edema in 1 studies
Etazolate: A potent phosphodiesterase inhibitor proposed as an antipsychotic agent.
etazolate : A pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Siopi, E | 1 |
| Llufriu-Dabén, G | 1 |
| Cho, AH | 1 |
| Vidal-Lletjós, S | 1 |
| Plotkine, M | 1 |
| Marchand-Leroux, C | 1 |
| Jafarian-Tehrani, M | 1 |
1 other study available for etazolate and Brain Edema
| Article | Year |
|---|---|
Etazolate, an α-secretase activator, reduces neuroinflammation and offers persistent neuroprotection following traumatic brain injury in mice.
Topics: Amyloid Precursor Protein Secretases; Animals; Brain Edema; Brain Injuries; Enzyme Activation; Etazo | 2013 |