etazolate has been researched along with Anxiety in 4 studies
Etazolate: A potent phosphodiesterase inhibitor proposed as an antipsychotic agent.
etazolate : A pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Etazolate is a selective phosphodiesterase-4 inhibitor that is specific for cAMP." | 5.46 | Evaluating the protective effect of etazolate on memory impairment, anxiety- and depression-like behaviors induced by post traumatic stress disorder. ( Al Subeh, ZY; Alzoubi, KH; Khabour, OF, 2017) |
| "Etazolate is a selective inhibitor of type 4 phosphodiesterase (PDE4) class enzyme." | 5.39 | Anxiolytic-like effect of etazolate, a type 4 phosphodiesterase inhibitor in experimental models of anxiety. ( Ankur, J; Bhatt, S; Mahesh, R, 2013) |
| "Etazolate treatment, on the other hand, led to prevention of changes in these oxidative stress biomarkers (GSH, GSSG, GPx and TBARS), BDNF levels, and histones acetylation." | 1.51 | Molecular targets for the interactive effect of etazolate during post-traumatic stress disorder: Role of oxidative stress, BDNF and histones. ( Al Subeh, ZY; Alzoubi, KH; Khabour, OF, 2019) |
| "Etazolate is a selective phosphodiesterase-4 inhibitor that is specific for cAMP." | 1.46 | Evaluating the protective effect of etazolate on memory impairment, anxiety- and depression-like behaviors induced by post traumatic stress disorder. ( Al Subeh, ZY; Alzoubi, KH; Khabour, OF, 2017) |
| "Etazolate is a selective inhibitor of type 4 phosphodiesterase (PDE4) class enzyme." | 1.39 | Anxiolytic-like effect of etazolate, a type 4 phosphodiesterase inhibitor in experimental models of anxiety. ( Ankur, J; Bhatt, S; Mahesh, R, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alzoubi, KH | 2 |
| Al Subeh, ZY | 2 |
| Khabour, OF | 2 |
| Ankur, J | 1 |
| Mahesh, R | 1 |
| Bhatt, S | 1 |
| Williams, M | 1 |
1 review available for etazolate and Anxiety
| Article | Year |
|---|---|
Anxioselective anxiolytics.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Benzodiazepines; Brain Chemi | 1983 |
3 other studies available for etazolate and Anxiety
| Article | Year |
|---|---|
Evaluating the protective effect of etazolate on memory impairment, anxiety- and depression-like behaviors induced by post traumatic stress disorder.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Animal; D | 2017 |
Molecular targets for the interactive effect of etazolate during post-traumatic stress disorder: Role of oxidative stress, BDNF and histones.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Animal; B | 2019 |
Anxiolytic-like effect of etazolate, a type 4 phosphodiesterase inhibitor in experimental models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Darkness; Diazepam; | 2013 |