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etazolate and Anxiety

etazolate has been researched along with Anxiety in 4 studies

Etazolate: A potent phosphodiesterase inhibitor proposed as an antipsychotic agent.
etazolate : A pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties.

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Etazolate is a selective phosphodiesterase-4 inhibitor that is specific for cAMP."5.46Evaluating the protective effect of etazolate on memory impairment, anxiety- and depression-like behaviors induced by post traumatic stress disorder. ( Al Subeh, ZY; Alzoubi, KH; Khabour, OF, 2017)
"Etazolate is a selective inhibitor of type 4 phosphodiesterase (PDE4) class enzyme."5.39Anxiolytic-like effect of etazolate, a type 4 phosphodiesterase inhibitor in experimental models of anxiety. ( Ankur, J; Bhatt, S; Mahesh, R, 2013)
"Etazolate treatment, on the other hand, led to prevention of changes in these oxidative stress biomarkers (GSH, GSSG, GPx and TBARS), BDNF levels, and histones acetylation."1.51Molecular targets for the interactive effect of etazolate during post-traumatic stress disorder: Role of oxidative stress, BDNF and histones. ( Al Subeh, ZY; Alzoubi, KH; Khabour, OF, 2019)
"Etazolate is a selective phosphodiesterase-4 inhibitor that is specific for cAMP."1.46Evaluating the protective effect of etazolate on memory impairment, anxiety- and depression-like behaviors induced by post traumatic stress disorder. ( Al Subeh, ZY; Alzoubi, KH; Khabour, OF, 2017)
"Etazolate is a selective inhibitor of type 4 phosphodiesterase (PDE4) class enzyme."1.39Anxiolytic-like effect of etazolate, a type 4 phosphodiesterase inhibitor in experimental models of anxiety. ( Ankur, J; Bhatt, S; Mahesh, R, 2013)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alzoubi, KH2
Al Subeh, ZY2
Khabour, OF2
Ankur, J1
Mahesh, R1
Bhatt, S1
Williams, M1

Reviews

1 review available for etazolate and Anxiety

ArticleYear
Anxioselective anxiolytics.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:5

    Topics: Adenosine; Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Benzodiazepines; Brain Chemi

1983

Other Studies

3 other studies available for etazolate and Anxiety

ArticleYear
Evaluating the protective effect of etazolate on memory impairment, anxiety- and depression-like behaviors induced by post traumatic stress disorder.
    Brain research bulletin, 2017, Volume: 135

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Animal; D

2017
Molecular targets for the interactive effect of etazolate during post-traumatic stress disorder: Role of oxidative stress, BDNF and histones.
    Behavioural brain research, 2019, 09-02, Volume: 369

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Anxiety Disorders; Behavior, Animal; B

2019
Anxiolytic-like effect of etazolate, a type 4 phosphodiesterase inhibitor in experimental models of anxiety.
    Indian journal of experimental biology, 2013, Volume: 51, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Darkness; Diazepam;

2013