etanidazole has been researched along with Sarcoma in 4 studies
Etanidazole: A nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.
etanidazole : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells.
Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with soft tissue sarcomas of the head and neck, extremity, trunk, or retroperitoneum for whom surgical excision was the initial treatment of choice, were given 21 mg/kg EF5 24-48 hours before surgery." | 1.33 | EF5 binding and clinical outcome in human soft tissue sarcomas. ( Evans, SM; Fraker, D; Gleason, K; Hahn, SM; Hwang, WT; Jenkins, K; Jenkins, WT; Koch, CJ; Mick, R; Zhang, P, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Busch, TM | 1 |
| Hahn, SM | 3 |
| Wileyto, EP | 1 |
| Koch, CJ | 3 |
| Fraker, DL | 2 |
| Zhang, P | 2 |
| Putt, M | 1 |
| Gleason, K | 2 |
| Shin, DB | 1 |
| Emanuele, MJ | 1 |
| Jenkins, K | 2 |
| Glatstein, E | 1 |
| Evans, SM | 3 |
| Salmon, HW | 1 |
| Siemann, DW | 1 |
| Fraker, D | 1 |
| Jenkins, WT | 2 |
| Hwang, WT | 1 |
| Mick, R | 1 |
| Magarelli, DP | 1 |
| Zhang, PJ | 1 |
| Hsi, RA | 1 |
| McKenna, WG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Imaging Tumor Hypoxia With 18F-EF5 PET in Recurrent or Metastatic Clear Cell Ovarian Cancer[NCT01881451] | 5 participants (Actual) | Observational | 2013-08-31 | Terminated (stopped due to Due to slow accrual and access to the study drug.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for etanidazole and Sarcoma
| Article | Year |
|---|---|
Hypoxia in human intraperitoneal and extremity sarcomas.
Topics: Adult; Aged; Cell Hypoxia; Etanidazole; Extremities; Female; Gastrointestinal Neoplasms; Humans; Hyd | 2001 |
3 other studies available for etanidazole and Sarcoma
| Article | Year |
|---|---|
Hypoxia and Photofrin uptake in the intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients.
Topics: Appendiceal Neoplasms; Benzimidazoles; Binding, Competitive; Carbocyanines; Colonic Neoplasms; Dihem | 2004 |
Utility of 19F MRS detection of the hypoxic cell marker EF5 to assess cellular hypoxia in solid tumors.
Topics: Animals; Antineoplastic Agents; Biomarkers; Cell Hypoxia; Etanidazole; Female; Fluorine Radioisotope | 2004 |
EF5 binding and clinical outcome in human soft tissue sarcomas.
Topics: Adult; Aged; Cell Hypoxia; Etanidazole; Female; Humans; Hydrocarbons, Fluorinated; Indicators and Re | 2006 |