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etanidazole and Prostatic Neoplasms

etanidazole has been researched along with Prostatic Neoplasms in 5 studies

Etanidazole: A nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.
etanidazole : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells.

Prostatic Neoplasms: Tumors or cancer of the PROSTATE.

Research Excerpts

ExcerptRelevanceReference
"RTOG Protocol 90-20 was designed to evaluate the effect of the hypoxic cell sensitizer Etanidazole (SR-2508) on locally advanced adenocarcinoma of the prostate treated with concurrent external beam irradiation."5.08Results of a phase II trial of external beam radiation with etanidazole (SR 2508) for the treatment of locally advanced prostate cancer (RTOG Protocol 90-20). ( Buzydlowski, JW; Coleman, CN; DelRowe, JD; Forman, JD; Lawton, CA; Marcial, VA; Rotman, M, 1996)
"Fifty eight previously untreated patients with locally advanced adenocarcinoma of the prostate were entered on a Phase II trial of etanidazole (ETA) combined with standard external beam radiation therapy."5.07Phase II trial of external beam radiation with etanidazole (SR 2508) for the treatment of locally advanced prostate cancer. ( Beard, C; Buswell, L; Coleman, CN; Johnson, D; Noll, L; Rose, MA, 1994)
" The secondary goal was to prospectively evaluate the utility of pharmacokinetic monitoring and dose-modification of the incidence and severity of the dose-limiting peripheral neurotoxicity."2.67The efficacy of pharmacokinetic monitoring and dose modification of etanidazole on the incidence of neurotoxicity: results from a phase II trial of etanidazole and radiation therapy in locally advanced prostate cancer. ( Buswell, L; Coleman, CN; Noll, L; Riese, N; Rose, MA, 1992)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoff, MN1
Yapp, DT1
Yung, AC1
Oliver, TS1
Kozlowski, P1
Beard, C2
Buswell, L3
Rose, MA2
Noll, L2
Johnson, D1
Coleman, CN3
Watkins-Bruner, D1
Scott, C1
Lawton, C1
DelRowe, J1
Rotman, M2
Cella, D1
Lawton, CA1
Buzydlowski, JW1
Forman, JD1
Marcial, VA1
DelRowe, JD1
Riese, N1

Trials

4 trials available for etanidazole and Prostatic Neoplasms

ArticleYear
Phase II trial of external beam radiation with etanidazole (SR 2508) for the treatment of locally advanced prostate cancer.
    International journal of radiation oncology, biology, physics, 1994, Jun-15, Volume: 29, Issue:3

    Topics: Adenocarcinoma; Etanidazole; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms

1994
RTOG's first quality of life study--RTOG 90-20: a phase II trial of external beam radiation with etanidazole for locally advanced prostate cancer.
    International journal of radiation oncology, biology, physics, 1995, Nov-01, Volume: 33, Issue:4

    Topics: Adenocarcinoma; Aged; Data Collection; Etanidazole; Feasibility Studies; Follow-Up Studies; Humans;

1995
Results of a phase II trial of external beam radiation with etanidazole (SR 2508) for the treatment of locally advanced prostate cancer (RTOG Protocol 90-20).
    International journal of radiation oncology, biology, physics, 1996, Oct-01, Volume: 36, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Etanidazole; Humans; Male; Middle Aged; Neoplasm Staging; P

1996
The efficacy of pharmacokinetic monitoring and dose modification of etanidazole on the incidence of neurotoxicity: results from a phase II trial of etanidazole and radiation therapy in locally advanced prostate cancer.
    International journal of radiation oncology, biology, physics, 1992, Volume: 22, Issue:3

    Topics: Adenocarcinoma; Combined Modality Therapy; Drug Evaluation; Etanidazole; Humans; Male; Nitroimidazol

1992

Other Studies

1 other study available for etanidazole and Prostatic Neoplasms

ArticleYear
In vivo measurement of the hypoxia marker EF5 in Shionogi tumours using (19)F magnetic resonance spectroscopy.
    International journal of radiation biology, 2008, Volume: 84, Issue:3

    Topics: Animals; Cell Hypoxia; Disease Models, Animal; Etanidazole; Female; Fluorine Radioisotopes; Hydrocar

2008