etanidazole has been researched along with Necrosis in 5 studies
Etanidazole: A nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.
etanidazole : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Necrosis was usually found adjacent to the highest level of binding in an individual patient's tumor." | 1.31 | Hypoxic heterogeneity in human tumors: EF5 binding, vasculature, necrosis, and proliferation. ( Evans, SM; Hahn, SM; Koch, CJ; Magarelli, DP, 2001) |
| " Pharmacokinetic studies were performed in six cats." | 1.28 | Technique, pharmacokinetics, toxicity, and efficacy of intratumoral etanidazole and radiotherapy for treatment of spontaneous feline oral squamous cell carcinoma. ( Brown, DQ; Curran, WJ; Evans, SM; Hanks, G; Helfand, S; LaCreta, F; VanWinkle, T, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vordermark, D | 1 |
| Jenkins, WT | 1 |
| Evans, SM | 3 |
| Koch, CJ | 2 |
| Li, YQ | 1 |
| Ballinger, JR | 1 |
| Nordal, RA | 1 |
| Su, ZF | 1 |
| Wong, CS | 1 |
| Hahn, SM | 1 |
| Magarelli, DP | 1 |
| LaCreta, F | 1 |
| Helfand, S | 1 |
| VanWinkle, T | 1 |
| Curran, WJ | 1 |
| Brown, DQ | 1 |
| Hanks, G | 1 |
5 other studies available for etanidazole and Necrosis
| Article | Year |
|---|---|
Significance of hypoxia in malignant glioma. Re: Evans et al. Hypoxia is important in the biology and aggression of human glial brain tumors. Clin Cancer Res 2004;10:8177-84.
Topics: Antineoplastic Agents; Brain Neoplasms; Etanidazole; Glioma; Humans; Hydrocarbons, Fluorinated; Hypo | 2005 |
Hypoxia and necrosis in rat 9L glioma and Morris 7777 hepatoma tumors: comparative measurements using EF5 binding and the Eppendorf needle electrode.
Topics: Animals; Cell Hypoxia; Etanidazole; Glioma; Hydrocarbons, Fluorinated; Indicators and Reagents; Ion- | 2000 |
Hypoxia in radiation-induced blood-spinal cord barrier breakdown.
Topics: Albumins; Animals; Blood-Brain Barrier; Capillary Permeability; Cell Hypoxia; Endothelial Growth Fac | 2001 |
Hypoxic heterogeneity in human tumors: EF5 binding, vasculature, necrosis, and proliferation.
Topics: Antineoplastic Agents; Cell Division; Cell Hypoxia; Clinical Trials, Phase I as Topic; Etanidazole; | 2001 |
Technique, pharmacokinetics, toxicity, and efficacy of intratumoral etanidazole and radiotherapy for treatment of spontaneous feline oral squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cat Diseases; Cats; Combined Modality Therapy; Etanidazole; Mouth | 1991 |