etanidazole has been researched along with Malignant Melanoma in 6 studies
Etanidazole: A nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.
etanidazole : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A study on the uptake and radiosensitizing properties of pimonidazole (PIMO) and etanidazole (ETA) was made in vitro with two melanoma cell lines: Na11+ and Na11-." | 7.68 | Relationship between intracellular concentration and radiosensitizing effect of pimonidazole and etanidazole on two human melanoma cell lines. ( el Gamoussi, R; Guichard, M; Stratford, IJ, 1993) |
| "The intra-cellular uptake of the weakly basic radiosensitiser pimonidazole (PIMO) was determined as a function of the pigmentation of Na11+ human melanotic melanoma cells in vitro." | 7.68 | Relationship between the melanin content of a human melanoma cell line and its radiosensitivity and uptake of pimonidazole. ( el Gamoussi, R; Guichard, M; Prade, M; Stratford, IJ; Threadgill, MD, 1993) |
| "The effect of treatments with the hypoxic cell radiosensitizers misonidazole (MISO), SR-2508, RSU-1069, and with the radioprotector WR-2721 on spontaneously disseminated Lewis lung carcinoma (LLC) and B16 melanoma (B16M) was investigated." | 7.67 | Influence of misonidazole, SR-2508, RSU-1069 and WR-2721 on spontaneous metastases in C57BL mice. ( Chapman, JD; Kanclerz, A, 1988) |
| "A study on the uptake and radiosensitizing properties of pimonidazole (PIMO) and etanidazole (ETA) was made in vitro with two melanoma cell lines: Na11+ and Na11-." | 3.68 | Relationship between intracellular concentration and radiosensitizing effect of pimonidazole and etanidazole on two human melanoma cell lines. ( el Gamoussi, R; Guichard, M; Stratford, IJ, 1993) |
| "The intra-cellular uptake of the weakly basic radiosensitiser pimonidazole (PIMO) was determined as a function of the pigmentation of Na11+ human melanotic melanoma cells in vitro." | 3.68 | Relationship between the melanin content of a human melanoma cell line and its radiosensitivity and uptake of pimonidazole. ( el Gamoussi, R; Guichard, M; Prade, M; Stratford, IJ; Threadgill, MD, 1993) |
| "The effect of treatments with the hypoxic cell radiosensitizers misonidazole (MISO), SR-2508, RSU-1069, and with the radioprotector WR-2721 on spontaneously disseminated Lewis lung carcinoma (LLC) and B16 melanoma (B16M) was investigated." | 3.67 | Influence of misonidazole, SR-2508, RSU-1069 and WR-2721 on spontaneous metastases in C57BL mice. ( Chapman, JD; Kanclerz, A, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Speicher, PJ | 1 |
| Beasley, GM | 1 |
| Jiang, B | 1 |
| Lidsky, ME | 1 |
| Palmer, GM | 1 |
| Scarbrough, PM | 1 |
| Mosca, PJ | 1 |
| Dewhirst, MW | 1 |
| Tyler, DS | 1 |
| el Gamoussi, R | 2 |
| Stratford, IJ | 2 |
| Guichard, M | 2 |
| Threadgill, MD | 1 |
| Prade, M | 1 |
| Taghian, A | 1 |
| Lespinasse, F | 1 |
| Guichard, ME | 1 |
| Kanclerz, A | 1 |
| Chapman, JD | 1 |
| Newman, HF | 1 |
| Bleehen, NM | 1 |
| Workman, P | 1 |
6 other studies available for etanidazole and Malignant Melanoma
| Article | Year |
|---|---|
Hypoxia in melanoma: using optical spectroscopy and EF5 to assess tumor oxygenation before and during regional chemotherapy for melanoma.
Topics: Aged; Antineoplastic Agents, Alkylating; Etanidazole; Feasibility Studies; Female; Follow-Up Studies | 2014 |
Relationship between intracellular concentration and radiosensitizing effect of pimonidazole and etanidazole on two human melanoma cell lines.
Topics: Etanidazole; Humans; In Vitro Techniques; Melanoma; Nitroimidazoles; Radiation-Sensitizing Agents; T | 1993 |
Relationship between the melanin content of a human melanoma cell line and its radiosensitivity and uptake of pimonidazole.
Topics: Animals; Autoradiography; Cell Line; Etanidazole; Humans; Melanins; Melanoma; Mice; Mice, Nude; Neop | 1993 |
Radiosensitization by the combination of etanidazole (SR-2508) and pimonidazole (Ro 03-8799) in human tumor xenografts.
Topics: Adenocarcinoma; Animals; Cell Survival; Drug Synergism; Etanidazole; Female; Humans; Melanoma; Mice; | 1991 |
Influence of misonidazole, SR-2508, RSU-1069 and WR-2721 on spontaneous metastases in C57BL mice.
Topics: Amifostine; Animals; Etanidazole; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Misonida | 1988 |
A phase I study of the combined hypoxic cell radiosensitizers, Ro 03-8799 and SR 2508: a preliminary report of single-dose toxicity, pharmacokinetics and tumour concentrations.
Topics: Adenocarcinoma; Drug Combinations; Drug Evaluation; Etanidazole; Humans; Melanoma; Nitroimidazoles; | 1986 |