etanidazole has been researched along with Leukopenia in 1 studies
Etanidazole: A nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.
etanidazole : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells.
Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The mean terminal half-life at each dose level ranged from 5." | 2.67 | Phase I/pharmacokinetic/biochemical study of the nitroimadazole hypoxic cell sensitiser SR2508 (etanidazole) in combination with cyclophosphamide. ( Comis, RL; Cox, T; Hoffman, JP; LaCreta, FP; Litwin, S; O'Dwyer, PJ; Walczak, J; Zimny, M, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Dwyer, PJ | 1 |
| LaCreta, FP | 1 |
| Walczak, J | 1 |
| Cox, T | 1 |
| Litwin, S | 1 |
| Hoffman, JP | 1 |
| Zimny, M | 1 |
| Comis, RL | 1 |
1 trial available for etanidazole and Leukopenia
| Article | Year |
|---|---|
Phase I/pharmacokinetic/biochemical study of the nitroimadazole hypoxic cell sensitiser SR2508 (etanidazole) in combination with cyclophosphamide.
Topics: Adult; Aged; Cyclophosphamide; Drug Administration Schedule; Etanidazole; Female; Glutathione; Gluta | 1993 |