Page last updated: 2024-10-26

etanidazole and Colorectal Neoplasms

etanidazole has been researched along with Colorectal Neoplasms in 2 studies

Etanidazole: A nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.
etanidazole : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells.

Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.

Research Excerpts

ExcerptRelevanceReference
"Pimonidazole was given 1h preheating, EF5 at various times during or after treatment, 1h later the animals were sacrificed."1.35Changes in tumor hypoxia induced by mild temperature hyperthermia as assessed by dual-tracer immunohistochemistry. ( Humm, JL; Li, GC; Li, XF; Ling, CC; Russell, J; Sun, X; Urano, M; Xing, L, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sun, X1
Li, XF1
Russell, J1
Xing, L1
Urano, M1
Li, GC1
Humm, JL1
Ling, CC1
Chitneni, SK1
Bida, GT1
Dewhirst, MW1
Zalutsky, MR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intraoperative Intraperitoneal Chemoperfusion to Treat Peritoneal Minimal Residual Disease in Stage III Ovarian Cancer: A Randomized Phase II Trial[NCT02567253]Phase 256 participants (Actual)Interventional2016-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for etanidazole and Colorectal Neoplasms

ArticleYear
Changes in tumor hypoxia induced by mild temperature hyperthermia as assessed by dual-tracer immunohistochemistry.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 88, Issue:2

    Topics: Adenocarcinoma; Analysis of Variance; Animals; Cell Hypoxia; Colorectal Neoplasms; Etanidazole; Fema

2008
A simplified synthesis of the hypoxia imaging agent 2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-[(18)F]pentafluoropropyl)-acetamide ([18F]EF5).
    Nuclear medicine and biology, 2012, Volume: 39, Issue:7

    Topics: Animals; Cell Hypoxia; Chemistry Techniques, Synthetic; Colorectal Neoplasms; Cyclotrons; Etanidazol

2012