etanidazole has been researched along with Cell Transformation, Neoplastic in 6 studies
Etanidazole: A nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.
etanidazole : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "H460 tumors showed higher tumor-to-muscle contrast in PET imaging; however, the distribution and uptake of the tracer was less specific for hypoxia in H460 than in HCT116 and PC3 tumors." | 1.40 | Comparison of the Hypoxia PET Tracer (18)F-EF5 to Immunohistochemical Marker EF5 in 3 Different Human Tumor Xenograft Models. ( Bida, GT; Chitneni, SK; Dewhirst, MW; Zalutsky, MR, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chitneni, SK | 3 |
| Bida, GT | 3 |
| Yuan, H | 1 |
| Palmer, GM | 1 |
| Hay, MP | 1 |
| Melcher, T | 1 |
| Wilson, WR | 1 |
| Zalutsky, MR | 3 |
| Dewhirst, MW | 3 |
| Koch, CJ | 1 |
| Evans, SM | 1 |
| Hall, EJ | 2 |
| Hei, TK | 2 |
6 other studies available for etanidazole and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
18F-EF5 PET imaging as an early response biomarker for the hypoxia-activated prodrug SN30000 combined with radiation treatment in a non-small cell lung cancer xenograft model.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Cell Proliferation; Cell Transformation, Neop | 2013 |
Comparison of the Hypoxia PET Tracer (18)F-EF5 to Immunohistochemical Marker EF5 in 3 Different Human Tumor Xenograft Models.
Topics: Animals; Benzimidazoles; Biological Transport; Cell Hypoxia; Cell Line, Tumor; Cell Transformation, | 2014 |
Reply: Pharmacokinetic and Pharmacodynamic Modifiers of EF5 Uptake and Binding.
Topics: Animals; Cell Transformation, Neoplastic; Etanidazole; Fluorine Radioisotopes; Humans; Hydrocarbons, | 2015 |
Pharmacokinetic and pharmacodynamic modifiers of EF5 uptake and binding.
Topics: Animals; Cell Transformation, Neoplastic; Etanidazole; Fluorine Radioisotopes; Humans; Hydrocarbons, | 2015 |
Oncogenic transforming potential of etanidazole.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Etanidazole; Mice; Neoplasms, Second Primary; N | 1992 |
Oncogenic transforming potential of nitroimidazole radiosensitizers.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Etanidazole; Mice; Misonidazole; Nitroimidazole | 1989 |