etanidazole has been researched along with Brain Stem Neoplasms in 1 studies
Etanidazole: A nitroimidazole that sensitizes hypoxic tumor cells that are normally resistant to radiation therapy.
etanidazole : A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells.
Brain Stem Neoplasms: Benign and malignant intra-axial tumors of the MESENCEPHALON; PONS; or MEDULLA OBLONGATA of the BRAIN STEM. Primary and metastatic neoplasms may occur in this location. Clinical features include ATAXIA, cranial neuropathies (see CRANIAL NERVE DISEASES), NAUSEA, hemiparesis (see HEMIPLEGIA), and quadriparesis. Primary brain stem neoplasms are more frequent in children. Histologic subtypes include GLIOMA; HEMANGIOBLASTOMA; GANGLIOGLIOMA; and EPENDYMOMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the toxicity and maximum tolerated dose of etanidazole administered concurrently with hyperfractionated radiation therapy (HRT) for children with brainstem glioma." | 9.10 | A phase I trial of etanidazole and hyperfractionated radiotherapy in children with diffuse brainstem glioma. ( Barnes, P; Billett, AL; Coleman, CN; Dutton, SC; Goumnerova, L; Kieran, M; Marcus, KJ; Pomeroy, SL; Tarbell, NJ, 2003) |
| "To determine the toxicity and maximum tolerated dose of etanidazole administered concurrently with hyperfractionated radiation therapy (HRT) for children with brainstem glioma." | 5.10 | A phase I trial of etanidazole and hyperfractionated radiotherapy in children with diffuse brainstem glioma. ( Barnes, P; Billett, AL; Coleman, CN; Dutton, SC; Goumnerova, L; Kieran, M; Marcus, KJ; Pomeroy, SL; Tarbell, NJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marcus, KJ | 1 |
| Dutton, SC | 1 |
| Barnes, P | 1 |
| Coleman, CN | 1 |
| Pomeroy, SL | 1 |
| Goumnerova, L | 1 |
| Billett, AL | 1 |
| Kieran, M | 1 |
| Tarbell, NJ | 1 |
1 trial available for etanidazole and Brain Stem Neoplasms
| Article | Year |
|---|---|
A phase I trial of etanidazole and hyperfractionated radiotherapy in children with diffuse brainstem glioma.
Topics: Adolescent; Adult; Antineoplastic Agents; Astrocytoma; Brain Stem Neoplasms; Child; Child, Preschool | 2003 |