eszopiclone has been researched along with Hot-Flashes* in 2 studies
1 trial(s) available for eszopiclone and Hot-Flashes
| Article | Year |
|---|---|
Eszopiclone improves insomnia and depressive and anxious symptoms in perimenopausal and postmenopausal women with hot flashes: a randomized, double-blinded, placebo-controlled crossover trial.
Menopause-associated insomnia is commonly associated with other symptoms (hot flashes, depression, anxiety). Given frequent symptom cooccurrence, therapies targeting sleep may provide an important approach to treatment during midlife.. Peri/postmenopausal women (40-65 years old) with sleep-onset and/or sleep-maintenance insomnia cooccurring with hot flashes and depressive and/or anxiety symptoms were randomized to eszopiclone 3 mg orally or placebo in a double-blinded, crossover 11 week trial. Changes in the Insomnia Severity Index (ISI) scale and secondary outcomes (diary-based sleep parameters, depression/anxiety, hot flashes, quality of life) were analyzed using repeated-measure linear models.. Of 59 women, 46 (78%) completed the study. Eszopiclone reduced ISI scores by 8.7 + or - 1.4 more points than placebo (P < .0001). Eszopiclone improved (P < .05) all sleep parameters, depressive symptoms, anxiety symptoms, quality of life, and nighttime but not daytime hot flashes.. Eszopiclone treats insomnia and cooccurring menopause-related symptoms. Our results provide evidence that hypnotic therapies may improve multiple domains of well-being during midlife. Topics: Adult; Aged; Anxiety; Azabicyclo Compounds; Cross-Over Studies; Depression; Double-Blind Method; Eszopiclone; Female; Hot Flashes; Humans; Hypnotics and Sedatives; Middle Aged; Perimenopause; Piperazines; Postmenopause; Quality of Life; Sleep Initiation and Maintenance Disorders | 2010 |
1 other study(ies) available for eszopiclone and Hot-Flashes
| Article | Year |
|---|---|
Menopause management: how you can do better.
Let patients know that hot flashes, vaginal dryness, and other common menopausal symptoms can be treated successfully with hormonal and nonhormonal agents. Topics: Acupuncture Therapy; Adjuvants, Immunologic; Administration, Cutaneous; Administration, Topical; Affect; Age Factors; Androgen Antagonists; Androgens; Antidepressive Agents; Antidepressive Agents, Second-Generation; Atrophic Vaginitis; Azabicyclo Compounds; Bupropion; Cyproterone Acetate; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Dyspareunia; Estrogens; Eszopiclone; Exercise; Female; Hair; Hormone Replacement Therapy; Hot Flashes; Humans; Hypnotics and Sedatives; Libido; Life Style; Lubricants; Menopause; Middle Aged; Mineralocorticoid Receptor Antagonists; Minoxidil; Phytotherapy; Piperazines; Sleep Initiation and Maintenance Disorders; Spironolactone; Testosterone | 2012 |