estrone has been researched along with Uterine Cervical Neoplasms in 23 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
Uterine Cervical Neoplasms: Tumors or cancer of the UTERINE CERVIX.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cervical cancer is the fourth most frequently diagnosed tumor and the fourth leading cause of cancer death in females worldwide." | 1.46 | Mechanism of antiproliferative action of a new d-secoestrone-triazole derivative in cervical cancer cells and its effect on cancer cell motility. ( Bózsity, N; Mernyák, E; Minorics, R; Ocsovszki, I; Schneider, G; Szabó, J; Wang, HC; Wölfling, J; Wu, CC; Zupkó, I, 2017) |
| "We considered that the presence of HPV infection probably increased 16 alpha-hydroxylation of estradiol, providing a possible link between the viral and hormonal elements, possibly having a bearing on the etiology of the disease." | 1.31 | Relationship between estradiol 16 alpha-hydroxylation and human papillomavirus infection in cervical cell transformation. ( Mercado, E; Salazar, EL; Salcedo, M; Sojo, I, 2001) |
| "E1/E2 ratio in cervical cancer patients was higher than that in normal postmenopausal women (P less than 0." | 1.28 | [Plasma estrogen level in patients with cervical cancer]. ( Zheng, Y, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (52.17) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Sepkovic, DW | 2 |
| Bradlow, HL | 2 |
| Ho, G | 1 |
| Hankinson, SE | 1 |
| Gong, L | 1 |
| Osborne, MP | 1 |
| Fishman, J | 1 |
| Bell, MC | 1 |
| Crowley-Nowick, P | 1 |
| Schmidt-Grimminger, D | 1 |
| Howell, P | 1 |
| Mayeaux, EJ | 1 |
| Tucker, A | 1 |
| Turbat-Herrera, EA | 1 |
| Mathis, JM | 1 |
| Salazar, EL | 1 |
| Mercado, E | 1 |
| Sojo, I | 1 |
| Salcedo, M | 1 |
| Li, Q | 1 |
| Zhu, M | 1 |
| Li, Y | 2 |
| Tang, H | 1 |
| Wang, Z | 1 |
| Zhang, Y | 1 |
| Xie, Y | 1 |
| Lv, Z | 1 |
| Bao, H | 1 |
| Liu, R | 1 |
| Shen, Y | 1 |
| Zheng, Y | 2 |
| Miao, D | 1 |
| Guo, X | 1 |
| Pei, J | 1 |
| Ali, H | 1 |
| Traj, P | 1 |
| Szebeni, GJ | 1 |
| Gémes, N | 1 |
| Resch, V | 1 |
| Paragi, G | 1 |
| Mernyák, E | 3 |
| Minorics, R | 3 |
| Zupkó, I | 3 |
| Mistry, S | 1 |
| Thakkar, M | 1 |
| Singh, AK | 1 |
| Patel, D | 1 |
| Tomaszewska, A | 1 |
| Roszak, A | 1 |
| Pawlik, P | 1 |
| Sajdak, S | 1 |
| Jagodziński, PP | 1 |
| Bózsity, N | 2 |
| Molnár, J | 1 |
| Wölfling, J | 2 |
| Schneider, G | 2 |
| Ocsovszki, I | 2 |
| Szabó, J | 1 |
| Wang, HC | 1 |
| Wu, CC | 1 |
| Fournier, MA | 1 |
| Poirier, D | 1 |
| BRENNER, G | 1 |
| PUCK, A | 1 |
| WINDEMUTH, W | 1 |
| LAJOS, L | 2 |
| GORCS, J | 1 |
| CSABA, I | 1 |
| DOMANY, S | 1 |
| SZEKELY, J | 1 |
| BREILA, I | 1 |
| LINDELL, A | 1 |
| RAUD, MO | 1 |
| SHE, MP | 1 |
| LIU, TH | 1 |
| CHANG, BR | 1 |
| CHENG, FL | 1 |
| SHEN, ZY | 1 |
| LIU, CM | 1 |
| WU, ER | 1 |
| Fraser, RC | 1 |
| Cudmore, DC | 1 |
| Malanson, J | 1 |
| Morse, WI | 1 |
| Jalůvka, V | 1 |
| Kratzsch, E | 1 |
| Grönroos, M | 1 |
| Klemi, P | 1 |
| Piiroinen, O | 1 |
| Erkkola, R | 1 |
| Nikkanen, V | 1 |
| Ruotsalainen, P | 1 |
| Hähnel, R | 1 |
| Martin, JD | 1 |
| Masters, AM | 1 |
| Ratajczak, T | 1 |
| Twaddle, E | 1 |
| Eby, NL | 1 |
| Boice, JD | 1 |
| Gold, EB | 1 |
| Hoover, RN | 1 |
| Loriaux, DL | 1 |
| Iakovleva, VV | 1 |
| Koga, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Single-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of 3,3'-Diindolylmethane (BR-DIM) in Patients With Systemic Lupus Erythematosus (SLE)[NCT02483624] | Phase 1 | 6 participants (Actual) | Interventional | 2016-01-31 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for estrone and Uterine Cervical Neoplasms
| Article | Year |
|---|---|
[Hormone activity of various Brenner tumors].
Topics: Aged; Breast Neoplasms; Brenner Tumor; Estradiol; Estrone; Female; Humans; Neoplasm Metastasis; Neop | 1982 |
1 trial available for estrone and Uterine Cervical Neoplasms
| Article | Year |
|---|---|
Placebo-controlled trial of indole-3-carbinol in the treatment of CIN.
Topics: Administration, Oral; Anticarcinogenic Agents; DNA, Viral; Dose-Response Relationship, Drug; Female; | 2000 |
21 other studies available for estrone and Uterine Cervical Neoplasms
| Article | Year |
|---|---|
Estrogen metabolite ratios and risk assessment of hormone-related cancers. Assay validation and prediction of cervical cancer risk.
Topics: Biopsy; Estriol; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Immunoenzyme Techniques; Mens | 1995 |
Relationship between estradiol 16 alpha-hydroxylation and human papillomavirus infection in cervical cell transformation.
Topics: Adolescent; Adult; Aryl Hydrocarbon Hydroxylases; Biopsy; Cell Transformation, Viral; Cytochrome P-4 | 2001 |
Estrone-targeted PEGylated Liposomal Nanoparticles for Cisplatin (DDP) Delivery in Cervical Cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Estrone; Female; HeLa Cells; Humans; Li | 2022 |
Investigation of the Antineoplastic Effects of 2-(4-Chlorophenyl)-13α-Estrone Sulfamate against the HPV16-Positive Human Invasive Cervical Carcinoma Cell Line SiHa.
Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Estrone; Female; | 2023 |
Synthesis, in vitro cytotoxic activity and molecular docking study of androstene and estrone derivatives.
Topics: Androstenes; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship | 2023 |
Increased 17ß-hydroxysteroid dehydrogenase type 1 levels in primary cervical cancer.
Topics: Cell Line, Tumor; Estradiol; Estradiol Dehydrogenases; Estrone; Female; Gene Expression Regulation, | 2015 |
A molecular understanding of D-homoestrone-induced G2/M cell cycle arrest in HeLa human cervical carcinoma cells.
Topics: Apoptosis; Caspase 8; Caspase 9; CDC2 Protein Kinase; Cell Proliferation; Cyclin B; Cyclin-Dependent | 2015 |
Mechanism of antiproliferative action of a new d-secoestrone-triazole derivative in cervical cancer cells and its effect on cancer cell motility.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; D | 2017 |
Estrogen formation in endometrial and cervix cancer cell lines: involvement of aromatase, steroid sulfatase and 17beta-hydroxysteroid dehydrogenases (types 1, 5, 7 and 12).
Topics: 17-Hydroxysteroid Dehydrogenases; Aromatase; Cell Line, Tumor; Endometrial Neoplasms; Estradiol; Est | 2009 |
[On the effect of operation and radiotherapy on the excretion of 17beta estradiol, estrone and estriol in the urine of sexually mature women with cancer of the cervix uteri].
Topics: Body Fluids; Contraceptive Agents, Female; Estradiol; Estradiol Congeners; Estriol; Estrogens; Estro | 1961 |
Pathological proliferation of the trophoblast homograft in women.
Topics: Allografts; Contraceptive Agents, Female; Ectoderm; Estrogens; Estrone; Female; Humans; Transplantat | 1962 |
THE MORPHOLOGY AND BIOLOGY OF THE ADENOHYPOPHYSIS AFTER OESTROGEN TREATMENT. (EXPERIMENTALLY INDUCED PREGNANCY CHANGES IN THE ADENOHYPOPHYSIS IN NON-PREGNANT SUBJECTS).
Topics: Anura; Chorionic Gonadotropin; Estrogens; Estrone; Female; Gonadotropins; Histology; Humans; Luteini | 1963 |
EXCRETION OF OESTROGENS, 17-KETOSTEROIDS AND 17-OH-CORTICOSTEROIDS IN IRRADIATED CERVICAL CARCINOMA.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Carcinoma; Carcinoma, Squamous Cell; Estradiol; Estriol; E | 1963 |
DETERMINATION OF URINARY ESTROGENS, PREGNANEDIOL, 17-OHCS, AND GONADOTROPINS IN PATIENTS WITH CARCINOMA OF THE CERVIX UTERI.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Estradiol; Estriol; Estrogens; Estrone; Female; | 1964 |
The metabolism and production rate of estradiol-17-beta in premenopausal women with cervical carcinoma.
Topics: Adult; Carcinoma; Estradiol; Estriol; Estrone; Female; Humans; Middle Aged; Tritium; Uterine Cervica | 1967 |
Ovarian function during and after curative intracavitary high dose-rate irradiation: steroidal output and morphology.
Topics: Adult; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Ovary; | 1982 |
Estrogen receptors and blood hormone levels in cervical carcinoma and other gynecological tumors.
Topics: Adult; Aged; DNA, Neoplasm; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Genital Neopla | 1979 |
[Plasma estrogen level in patients with cervical cancer].
Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Estradiol; Estriol; Estrogens; Estrone; Female; Huma | 1990 |
Estrogen and androgen levels in women treated with radiation for cervical cancer--possible influence on breast cancer risk.
Topics: Adult; Aged; Androstenedione; Breast Neoplasms; Cross-Sectional Studies; Estradiol; Estrone; Female; | 1989 |
[Excretion of classic estrogens and total phenol steroids in patients with cancer of the uterine cervix].
Topics: Adult; Cell Nucleus; Chromatography, Thin Layer; Cobalt Radioisotopes; Estradiol; Estriol; Estrogens | 1974 |
[Hormonal therapy in cervical cancer, with special reference to the acceleration of radiosensitivity].
Topics: Cobalt Isotopes; Cortisone; Culture Techniques; Estradiol; Estriol; Estrone; Female; HeLa Cells; Hum | 1965 |