estrone has been researched along with Pulmonary Hypertension in 4 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aromatase inhibitor anastrozole blocks the conversion of androgens to estrogen and blunts pulmonary hypertension in animals, but its efficacy in treating patients with pulmonary arterial hypertension (PAH) is unknown." | 5.24 | Anastrozole in Pulmonary Arterial Hypertension. A Randomized, Double-Blind, Placebo-controlled Trial. ( Archer-Chicko, CL; DeMichele, A; Fritz, JS; Kawut, SM; Klinger, JR; Ky, B; Palevsky, HI; Palmisciano, AJ; Patel, M; Pinder, D; Propert, KJ; Smith, KA; Stanczyk, F; Tracy, R; Vaidya, A; Ventetuolo, CE; Whittenhall, ME, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X | 1 |
| Talati, M | 1 |
| Fessel, JP | 1 |
| Hemnes, AR | 1 |
| Gladson, S | 1 |
| French, J | 1 |
| Shay, S | 1 |
| Trammell, A | 1 |
| Phillips, JA | 1 |
| Hamid, R | 1 |
| Cogan, JD | 1 |
| Dawson, EP | 1 |
| Womble, KE | 1 |
| Hedges, LK | 1 |
| Martinez, EG | 1 |
| Wheeler, LA | 1 |
| Loyd, JE | 1 |
| Majka, SJ | 1 |
| West, J | 1 |
| Austin, ED | 1 |
| Hood, KY | 1 |
| Montezano, AC | 1 |
| Harvey, AP | 1 |
| Nilsen, M | 2 |
| MacLean, MR | 2 |
| Touyz, RM | 1 |
| White, K | 1 |
| Johansen, AK | 1 |
| Ciuclan, L | 1 |
| Wallace, E | 1 |
| Paton, L | 1 |
| Campbell, A | 1 |
| Morecroft, I | 1 |
| Loughlin, L | 1 |
| McClure, JD | 1 |
| Thomas, M | 1 |
| Mair, KM | 1 |
| Kawut, SM | 1 |
| Archer-Chicko, CL | 1 |
| DeMichele, A | 1 |
| Fritz, JS | 1 |
| Klinger, JR | 1 |
| Ky, B | 1 |
| Palevsky, HI | 1 |
| Palmisciano, AJ | 1 |
| Patel, M | 1 |
| Pinder, D | 1 |
| Propert, KJ | 1 |
| Smith, KA | 1 |
| Stanczyk, F | 1 |
| Tracy, R | 1 |
| Vaidya, A | 1 |
| Whittenhall, ME | 1 |
| Ventetuolo, CE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-blind, Placebo-controlled Phase II Study of Anastrozole in Patients With Pulmonary Arterial Hypertension[NCT01545336] | Phase 2 | 18 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01545336)
Timeframe: Baseline, 3 months
| Intervention | % change from baseline (Median) |
|---|---|
| Anastrozole | -40 |
| Placebo | -4 |
(NCT01545336)
Timeframe: Baseline, 3 months
| Intervention | % change from baseline (Median) |
|---|---|
| Anastrozole | 8 |
| Placebo | -2 |
(NCT01545336)
Timeframe: Baseline, 3 months
| Intervention | % change from baseline (Median) |
|---|---|
| Anastrozole | 7 |
| Placebo | 10 |
1 trial available for estrone and Pulmonary Hypertension
| Article | Year |
|---|---|
Anastrozole in Pulmonary Arterial Hypertension. A Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Anastrozole; Aromatase Inhibitors; Biomarkers; Double-Blind Method; Estradiol; Estrone; Female; Gona | 2017 |
3 other studies available for estrone and Pulmonary Hypertension