estrone has been researched along with Precancerous Conditions in 8 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
Precancerous Conditions: Pathological conditions that tend eventually to become malignant.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Occult hypothyroidism reduces the rate of oestrogen inactivation by C2 hydroxylation, and 15-20% of women have low rates of C16 hydroxylation to oestriol." | 4.76 | Pathophysiologic considerations in the treatment of menopausal patients with oestrogens; the role of oestriol in the prevention of mammary carcinoma. ( Lemon, HM, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, MC | 1 |
| Crowley-Nowick, P | 1 |
| Bradlow, HL | 1 |
| Sepkovic, DW | 1 |
| Schmidt-Grimminger, D | 1 |
| Howell, P | 1 |
| Mayeaux, EJ | 1 |
| Tucker, A | 1 |
| Turbat-Herrera, EA | 1 |
| Mathis, JM | 1 |
| Lemon, HM | 2 |
| Godefroi, VC | 1 |
| Locke, ER | 1 |
| Singh, DV | 1 |
| Brooks, SC | 2 |
| Biancifiori, C | 1 |
| Vellios, F | 1 |
| Gambrell, RD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Single-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of 3,3'-Diindolylmethane (BR-DIM) in Patients With Systemic Lupus Erythematosus (SLE)[NCT02483624] | Phase 1 | 6 participants (Actual) | Interventional | 2016-01-31 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for estrone and Precancerous Conditions
| Article | Year |
|---|---|
Pathophysiologic considerations in the treatment of menopausal patients with oestrogens; the role of oestriol in the prevention of mammary carcinoma.
Topics: Adolescent; Adult; Aged; Animals; Breast Neoplasms; Estradiol; Estriol; Estrogens; Estrone; Female; | 1980 |
The metabolism of steroid hormones in breast cancer: a reappraisal.
Topics: Androgens; Androsterone; Breast Neoplasms; Cytochrome P-450 Enzyme System; Estradiol; Estriol; Estro | 1976 |
Endometrial hyperplasias, precursors of endometrial carcinoma.
Topics: Adenocarcinoma; Carcinoma; Diagnosis, Differential; Endometrium; Epithelium; Estrogens; Estrone; Fem | 1972 |
1 trial available for estrone and Precancerous Conditions
| Article | Year |
|---|---|
Placebo-controlled trial of indole-3-carbinol in the treatment of CIN.
Topics: Administration, Oral; Anticarcinogenic Agents; DNA, Viral; Dose-Response Relationship, Drug; Female; | 2000 |
4 other studies available for estrone and Precancerous Conditions
| Article | Year |
|---|---|
The steroid alcohol and estrogen sulfotransferases in rodent and human mammary tumors.
Topics: Alcohols; Animals; Breast Neoplasms; Castration; Chick Embryo; Dehydroepiandrosterone; Estrogens; Es | 1975 |
[Morphology of the collateral mammae in induced mammary carcinoma in BALB/c/Cb/Se mice].
Topics: Animals; Castration; Estrone; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experi | 1977 |
Postmenopausal bleeding.
Topics: Adenocarcinoma; Adrenal Glands; Estradiol; Estrogens; Estrone; Ethinyl Estradiol; Female; Humans; Me | 1974 |
Genetic predisposition to carcinoma of the breast: multiple human genotypes for estrogen 16 alpha hydroxylase activity in Caucasians.
Topics: Breast Diseases; Breast Neoplasms; Estradiol; Estriol; Estrone; Female; Genital Neoplasms, Female; G | 1972 |