Page last updated: 2024-11-07

estrone and Obesity

estrone has been researched along with Obesity in 126 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"The present study was designed to investigate the influence of body weight on the prolactin responsiveness to metoclopramide and thyrotrophin-releasing hormone (TRH) in secondary amenorrhoeic women."9.07Effects of body weight on responses of serum prolactin to metoclopramide and thyrotrophin-releasing hormone in secondary amenorrhoeic women. ( Aono, T; Higuchi, K; Morishita, H; Takemoto, M; Yoshida, J, 1994)
"Oleoyl-estrone (OE) has been presented as a potential antiobesity therapeutic, but the published series of studies from one laboratory has not yet been independently confirmed, and the exact mechanism of action is unknown."7.76Action profile of the antiobesity drug candidate oleoyl-estrone in rats. ( Anker, SD; Chaudhary, N; Nogueiras, R; Perez-Tilve, D; Pfluger, PT; Strassburg, S; Tschöp, MH; Tso, P, 2010)
"To determine whether or not the long-term intermittent treatment with oleoyl-estrone (OE) in rats induces a cumulative weight loss, adult male rats were treated with OE over three alternating 10-day periods, with a 30-day "recovery" period occurring between each period."7.73Weight loss with long-term intermittent treatment with oral oleoyl-estrone in lean Zucker male rats. ( García-Peláez, B; Gómez-Ollés, S; Remesar, X; Salas, A, 2006)
"Treatment of genetically obese rats with oleoyl-estrone in liposomes (Merlin-2) results in sustained loss of body weight-mainly lipid, sparing protein-for up to 28 d, essentially preventing further increase in body weight and accumulation of lipid and protein."7.69Effect of the slimming agent oleoyl-estrone in liposomes on the body weight of Zucker obese rats. ( Alemany, M; Balada, F; Estruch, J; Fernández-López, JA; Grasa, MM; Remesar, X; Sanchis, D; Virgili, J, 1997)
"The effects of aging as well as body weight on conversion of circulating Androstendione (A) to Estrone (E1) in 21 postmenopausal women of different ages and body weights have been studied."7.67[Effects of age and obesity on the conversion of androstenedione to estrone in postmenopausal women]. ( Ortega, E; Osorio, C; Ruiz, E, 1988)
"The purpose of this study was to ascertain if a relationship exists between the transfer constant of conversion of plasma androstenedione to estrone ([rho]AE1BU) and total body weight or excessive body weight in 50 postmenopausal women, of whom 25 had adenocarcinoma of the endometrium and 25 had no endometrial disease."7.66Effect of obesity on conversion of plasma androstenedione to estrone in postmenopausal women with and without endometrial cancer. ( Edman, CD; Hemsell, DL; MacDonald, PC; Porter, JC; Siiteri, PK, 1978)
"Estrone is a relatively abundant hormone widely distributed in tissues of animal and plant origin."5.30Estrone in food: a factor influencing the development of obesity? ( Alemany, M; Fernández-López, JA; Ferrer, E; Masanés, RM; Remesar, X; Tang, V; Torregrosa, C; Virgili, J, 1999)
" Serum sex hormone binding globulin increased and leptin decreased with weight loss (P < 0."5.09Moderate energy restriction increases bone resorption in obese postmenopausal women. ( Chowdhury, HA; Heymsfield, SB; Pierson, RN; Ricci, TA; Shapses, SA; Stahl, T, 2001)
"The present study was designed to investigate the influence of body weight on the prolactin responsiveness to metoclopramide and thyrotrophin-releasing hormone (TRH) in secondary amenorrhoeic women."5.07Effects of body weight on responses of serum prolactin to metoclopramide and thyrotrophin-releasing hormone in secondary amenorrhoeic women. ( Aono, T; Higuchi, K; Morishita, H; Takemoto, M; Yoshida, J, 1994)
"At menopause, several abnormalities in oestrogen metabolism have been reported, which may increase the likelihood of cancer development in the breast or uterus following oestrone or oestradiol-17 beta supplementation."4.76Pathophysiologic considerations in the treatment of menopausal patients with oestrogens; the role of oestriol in the prevention of mammary carcinoma. ( Lemon, HM, 1980)
" Herein, we assessed if oestrogens, including oestrone (E1), oestradiol (E2) and oestriol (E3), are associated with A-FABP in the obesity-related BC development."3.91A-FABP and oestrogens are independently involved in the development of breast cancer. ( Hao, J; Kong, M; Li, B; Sauter, ER; Yan, X, 2019)
"Oleoyl-estrone (OE) has been presented as a potential antiobesity therapeutic, but the published series of studies from one laboratory has not yet been independently confirmed, and the exact mechanism of action is unknown."3.76Action profile of the antiobesity drug candidate oleoyl-estrone in rats. ( Anker, SD; Chaudhary, N; Nogueiras, R; Perez-Tilve, D; Pfluger, PT; Strassburg, S; Tschöp, MH; Tso, P, 2010)
"To determine whether or not the long-term intermittent treatment with oleoyl-estrone (OE) in rats induces a cumulative weight loss, adult male rats were treated with OE over three alternating 10-day periods, with a 30-day "recovery" period occurring between each period."3.73Weight loss with long-term intermittent treatment with oral oleoyl-estrone in lean Zucker male rats. ( García-Peláez, B; Gómez-Ollés, S; Remesar, X; Salas, A, 2006)
"We studied the associations between body mass index (BMI), body fat mass, and percent body fat, measured by dual-energy x-ray absorptiometry scan, waist circumference, and waist-to-hip circumference ratio, with concentrations of estrone, estradiol, testosterone, SHBG, dehydroepiandrosterone sulfate, free estradiol, and free testosterone in 505 postmenopausal women in western Washington and New Mexico with incident stage 0 to IIIA breast cancer."3.72Adiposity and sex hormones in postmenopausal breast cancer survivors. ( Ballard-Barbash, R; Baumgartner, R; Bernstein, L; Gilliland, F; Irwin, M; McTiernan, A; Rajan, KB; Stanczyk, FZ; Tworoger, SS; Yasui, Y, 2003)
"To test whether oleoyl-estrone affects body weight when given orally, which may help curtail the secondary growth-boosting effects of derived estrone."3.70Oral oleoyl-estrone induces the rapid loss of body fat in Zucker lean rats fed a hyperlipidic diet. ( Alemany, M; Fernández-López, JA; Grasa, MM; Guijarro, P; López, J; Remesar, X; Torregrosa, C, 2000)
"Studies in our laboratory and elsewhere have demonstrated numerous abnormalities of steroid and polypeptide hormone secretion in obesity: hyperestrogenemia and hypogonadotropic hypogonadism in obese men; diminished SHBG levels in both sexes; elevated free testosterone and free estradiol in obese women; PCOS-like gonadotropin and sex-hormone abnormalities in obese women; elevated serum insulin in both sexes; blunted stimulability of prolactin, growth hormone, and vasopressin in both sexes; and elevated basal levels and blunted stimulability and suppressibility of beta-endorphin in both sexes."3.69A perspective on the hormonal abnormalities of obesity: are they cause or effect? ( Strain, GW; Zumoff, B, 1994)
"Treatment of genetically obese rats with oleoyl-estrone in liposomes (Merlin-2) results in sustained loss of body weight-mainly lipid, sparing protein-for up to 28 d, essentially preventing further increase in body weight and accumulation of lipid and protein."3.69Effect of the slimming agent oleoyl-estrone in liposomes on the body weight of Zucker obese rats. ( Alemany, M; Balada, F; Estruch, J; Fernández-López, JA; Grasa, MM; Remesar, X; Sanchis, D; Virgili, J, 1997)
"Hyperestronemia may be central to the development of polycystic ovary syndrome."3.68Sex steroids, adiposity and smoking in the pathogenesis of idiopathic hirsutism and polycystic ovary syndrome. ( Byrne, B; Conroy, R; Cunningham, S; Igoe, D; McKenna, TJ, 1991)
"Levels of circulating estrone (E1), estradiol (E2), androst-4-ene-3,17-dione (Adione), 3,5,3'-triiodothyronine (T3), thyroxine (T4), and sex hormone-binding globulin (SHBG) were measured in 10 obese postmenopausal patients with breast cancer and in 10 obese postmenopausal control subjects matched for age, body size, and menopausal status."3.67Decrease of circulating level of SHBG in postmenopausal obese women as a risk factor in breast cancer: reversible effect of weight loss. ( Cardillo, LR; del Carmen Cremona, M; Enriori, CL; Etkin, AE; Orsini, W; Reforzo-Membrives, J, 1986)
"To study the ability of weight loss to reverse the hyperestrogenemia-induced hypogonadotropic hypogonadism that occurs in obese men, we measured the 24-h mean plasma free and total estradiol (E2), total estrone, FSH, LH, and free and total testosterone concentrations in 11 healthy obese men (100-305% above desirable body weight) and again 5-39 months later after weight loss of 26-129 kg and restabilization at the new weight."3.67Effect of massive weight loss on hypothalamic-pituitary-gonadal function in obese men. ( Hershcopf, RJ; Kalin, M; Levit, C; Miller, LK; Rosenfeld, RS; Rosner, W; Strain, GW; Zumoff, B, 1988)
"The effects of aging as well as body weight on conversion of circulating Androstendione (A) to Estrone (E1) in 21 postmenopausal women of different ages and body weights have been studied."3.67[Effects of age and obesity on the conversion of androstenedione to estrone in postmenopausal women]. ( Ortega, E; Osorio, C; Ruiz, E, 1988)
"001% estrone in a diet to C57BL/KsJ mice homozygous for the recessive obesity gene "diabetes" (db) permitted dissociation of the primary consequences of obesity gene expression from the secondary consequences of diabetes effected through interaction between the db gene and other diabetogenic genes in the inbred background."3.67Estrone treatment dissociates primary versus secondary consequences of "diabetes" (db) gene expression in mice. ( Leiter, EH; Lipson, LG; Premdas, FH; Prochazka, M, 1986)
" In this paper, we describe three of our findings relating nutrition to hormone levels: (a) that obesity causes retention of a tracer of estradiol in women but not in men, a finding we attribute to the presence of specific estrogen receptor in the adipose tissue of women but not men; (b) that obese men have elevated plasma estrone and estradiol levels but obese women do not, a finding we attribute to greater androstenedione-to-estrone conversion in the adipose tissue of men than in that of women; and (c) that cachectic girls with anorexia nervosa fail to have the normal nocturnal surge of prolactin secretion, a finding that we attribute to deficiency of tryptophan, which is an adequate stimulus for prolactin secretion."3.66Influence of obesity and malnutrition on the metabolism of some cancer-related hormones. ( Zumoff, B, 1981)
"The purpose of this study was to ascertain if a relationship exists between the transfer constant of conversion of plasma androstenedione to estrone ([rho]AE1BU) and total body weight or excessive body weight in 50 postmenopausal women, of whom 25 had adenocarcinoma of the endometrium and 25 had no endometrial disease."3.66Effect of obesity on conversion of plasma androstenedione to estrone in postmenopausal women with and without endometrial cancer. ( Edman, CD; Hemsell, DL; MacDonald, PC; Porter, JC; Siiteri, PK, 1978)
"Plasma sex hormone concentrations (testosterone, (T), androstenedione (A), oestrone (E1) and oestradiol (E2) were measured in forty post-menopausal women more than 4 years post-normal menopause."3.66Sex hormone concentrations in post-menopausal women. ( Verdonck, L; Vermeulen, A, 1978)
"To investigate the influence of obesity on hormonal parameters in 186 apparently healthy women and in 176 women suffering from severe obesity the serum concentrations of FSH, LH, estrone (E1), estradiol (E2), androstenedione (A) and testosterone (T) were determined radioimmunologically."3.66Influence of severe obesity on peripheral hormone concentrations in pre- and postmenopausal women. ( Klinga, K; Runnebaum, B; von Holst, T, 1983)
" The excess is reflected in obesity and the consequent overproduction of estrone, a natural but carcinogenic human estrogen."3.65Diet and cancer of endocrine target organs. ( Cole, P; Cramer, D, 1977)
" The possibility does exist that the SHBG level increase and the IGF-I bioavailability decrease, caused by oral CEE, balance the increased estrogen stimulation on breast tissue."2.40Conjugated estrogens and breast cancer risk. ( Ambroggio, S; Biglia, N; Campagnoli, C; Sismondi, P, 1999)
"Thus, steroid indices of relative cancer risk or responsiveness must be constructed with due attention to obesity, one of many important variables."2.35Hormones, nutrition, and cancer. ( Lipsett, MB, 1975)
"Obesity is an established risk factor for postmenopausal breast cancer (BCa), insulin resistance, and vitamin D deficiency, and all contribute to increased synthesis of mammary estrogens, the drivers of estrogen receptor-positive (ER+) BCa growth."1.43Vitamin D mitigates the adverse effects of obesity on breast cancer in mice. ( Aggarwal, A; Albertelli, MA; Feldman, BJ; Feldman, D; Horst, RL; Krishnan, AV; Swami, S; Williams, J, 2016)
"Obesity often accompanies hyperlipemia, which is strongly related to the occurrence and development of obesity-related chronic diseases."1.43Metabolomic analysis of serum from obese adults with hyperlipemia by UHPLC-Q-TOF MS/MS. ( Cui, Y; Guo, L; Li, E; Li, Y; Liu, D; Wang, Y; Zhang, X, 2016)
"A threshold of weight loss is necessary to improve male reproductive function by reversing male hypogonadism, manifested as increased testosterone levels."1.42Time-related increase in urinary testosterone levels and stable semen analysis parameters after bariatric surgery in men. ( Cooney, RN; Kesner, JS; Krieg, EF; Kunselman, AR; Legro, RS; Meadows, JW; Rogers, AM, 2015)
"Obesity is associated with metabolic dysfunction with sex differences and chronic, low-grade inflammation."1.40Complement receptors C5aR and C5L2 are associated with metabolic profile, sex hormones, and liver enzymes in obese women pre- and postbariatric surgery. ( Cianflone, K; Lapointe, M; Marceau, P; Rezvani, R; Smith, J; Tchernof, A, 2014)
"Estrone was positively associated with smoking, BMI, and testosterone, and total and free estradiol with diabetes, BMI, testosterone, and comorbid conditions; additionally, free estradiol was associated negatively with smoking."1.39Age trends in estradiol and estrone levels measured using liquid chromatography tandem mass spectrometry in community-dwelling men of the Framingham Heart Study. ( Basaria, S; Bhasin, S; Coviello, A; D'Agostino, R; Davda, M; Jasuja, GK; Kushnir, MM; Meikle, W; Murabito, JM; Pencina, MJ; Rockwood, AL; Rose, AJ; Travison, TG; Vasan, RS; Zhang, A, 2013)
"Acyl-estrone levels were lower than expected in most obese women when compared to those of controls, suggesting an altered availability or function of this hormone."1.31Plasma acyl-estrone levels are altered in obese women. ( Alemany, M; Bullo, M; Cabot, C; Fernández-López, JA; García-Lorda, P; Masanés, R; Salas-Salvadó, J, 2000)
"Estrone was better retained by white adipose tissue than oleoyl-estrone."1.30Differential short-term distribution of estrone and oleoyl-estrone administered in liposomes to lean and obese Zucker rats. ( Alemany, M; Balada, F; Estruch, J; Fernández-López, JA; Grasa, MM; Remesar, X; Sanchis, D; Virgili, J, 1998)
"The estrone concentration was estimated in tissue of endometrial cancer and in the serum of 103 postmenopausal women."1.29[Estrone concentration in endometrial cancer tissue in relation to body mass]. ( Kotarski, J, 1994)
"In vivo insulin resistance was observed in both nonobese (P less than 0."1.28Insulin and insulin-like growth factor-I responsiveness in polycystic ovarian syndrome. ( Bergman, RN; Bersch, N; Buyalos, RP; Geffner, ME; Golde, DW; Judd, HL; Watanabe, RM, 1992)
"Diazoxide treatment resulted in suppressed insulin release during a 100-g oral glucose tolerance test (insulin area under the curve, 262 +/- 55 nmol/min."1.28A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome. ( Blackard, WG; Clore, JN; Matt, DW; Nestler, JE; Plymate, SR; Powers, LP; Rittmaster, RS; Steingold, KA, 1991)
"Estrone was positively and significantly associated with high density lipoprotein cholesterol (r = 0."1.28Associations of abdominal adiposity, fasting insulin, sex hormone binding globulin, and estrone with lipids and lipoproteins in post-menopausal women. ( Folsom, AR; Kaye, SA; Prineas, RJ; Soler, JT, 1989)
"Obesity is a physiological state associated with alterations in hormone production and metabolism."1.26Obesity, hormones, and cancer. ( Ertel, N; Kirschner, MA; Schneider, G, 1981)
"Estrone was detected in cerebrospinal fluid before and after but not during dexamethasone treatment."1.26Pseudotumor cerebri in an obese woman with Turner syndrome. ( Binstock, ML; Donaldson, JO, 1981)

Research

Studies (126)

TimeframeStudies, this research(%)All Research%
pre-199054 (42.86)18.7374
1990's27 (21.43)18.2507
2000's31 (24.60)29.6817
2010's13 (10.32)24.3611
2020's1 (0.79)2.80

Authors

AuthorsStudies
Wang, Y1
Liu, D1
Li, Y1
Guo, L1
Cui, Y1
Zhang, X1
Li, E1
Michnovicz, JJ1
Aladhami, AK1
Unger, CA1
Hope, MC1
Cotham, WE1
Velázquez, KT1
Enos, RT1
Davis, SR1
Bell, RJ1
Robinson, PJ1
Handelsman, DJ1
Gilbert, T1
Phung, J1
Desai, R1
Lockery, JE1
Woods, RL1
Wolfe, RS1
Reid, CM1
Nelson, MR1
Murray, AM1
McNeil, JJ1
Li, B1
Hao, J1
Yan, X1
Kong, M1
Sauter, ER1
Ross, LA1
Polotsky, AJ1
Kucherov, A1
Bradford, AP1
Lesh, J1
Chosich, J1
Gee, N1
Santoro, N1
Rezvani, R1
Smith, J1
Lapointe, M1
Marceau, P1
Tchernof, A1
Cianflone, K1
Legro, RS1
Kunselman, AR1
Meadows, JW1
Kesner, JS1
Krieg, EF1
Rogers, AM1
Cooney, RN1
Swami, S1
Krishnan, AV1
Williams, J1
Aggarwal, A1
Albertelli, MA1
Horst, RL1
Feldman, BJ1
Feldman, D1
Mason, C1
De Dieu Tapsoba, J1
Duggan, C1
Imayama, I1
Wang, CY1
Korde, LA1
Stanczyk, F1
McTiernan, A2
García-Peláez, B3
Vilà, R5
Remesar, X20
Karim, R1
Mack, WJ1
Hodis, HN1
Roy, S1
Stanczyk, FZ2
Strassburg, S1
Pfluger, PT1
Chaudhary, N1
Tso, P1
Tschöp, MH1
Anker, SD1
Nogueiras, R1
Perez-Tilve, D1
Drabkin, HA1
Gemmill, RM1
Fernández-López, JA20
Alemany, M21
Jasuja, GK1
Travison, TG1
Davda, M1
Murabito, JM1
Basaria, S1
Zhang, A1
Kushnir, MM1
Rockwood, AL1
Meikle, W1
Pencina, MJ1
Coviello, A1
Rose, AJ1
D'Agostino, R1
Vasan, RS1
Bhasin, S1
Carpenter, CL1
Duvall, K1
Jardack, P1
Li, L1
Henning, SM1
Li, Z1
Heber, D1
Figueroa, A1
Going, SB1
Milliken, LA1
Blew, R1
Sharp, S1
Lohman, TG1
Ossewaarde, ME1
Bots, ML1
van der Schouw, YT1
Thijssen, JH1
Westerveld, HT1
de Jong, FH1
Grobbee, DE1
Massanés, RM1
Grasa, MM10
López-Martí, J1
Díaz-Silva, M3
Rajan, KB1
Tworoger, SS1
Irwin, M1
Bernstein, L1
Baumgartner, R1
Gilliland, F1
Yasui, Y1
Ballard-Barbash, R1
TWOMBLY, GH2
SCHEINER, S1
LEVITZ, M2
BROWN, JB1
STRONG, JA1
Zumoff, B8
Miller, LK3
Strain, GW5
Eagleson, CA1
Bellows, AB1
Hu, K1
Gingrich, MB1
Marshall, JC1
Lukanova, A1
Lundin, E1
Zeleniuch-Jacquotte, A1
Muti, P1
Mure, A1
Rinaldi, S1
Dossus, L1
Micheli, A1
Arslan, A1
Lenner, P1
Shore, RE1
Krogh, V1
Koenig, KL1
Riboli, E1
Berrino, F1
Hallmans, G1
Stattin, P1
Toniolo, P1
Kaaks, R1
McCarthy, AA1
Posadas, MD1
Olguín, MC1
Zingale, MI1
Revelant, G1
Labourdette, V1
Gayol, Mdel C1
Calderari, S1
Jacobson, PB1
von Geldern, TW1
Ohman, L1
Osterland, M1
Wang, J1
Zinker, B1
Wilcox, D1
Nguyen, PT1
Mika, A1
Fung, S1
Fey, T1
Goos-Nilsson, A1
Grynfarb, M1
Barkhem, T1
Marsh, K1
Beno, DW1
Nga-Nguyen, B1
Kym, PR1
Link, JT1
Tu, N1
Edgerton, DS1
Cherrington, A1
Efendic, S1
Lane, BC1
Opgenorth, TJ1
Ferrer-Lorente, R3
Cabot, C10
Blay, M3
Romero, MM1
Esteve, M4
Gómez-Ollés, S1
Salas, A1
Olson, MB1
Shaw, LJ1
Kaizar, EE1
Kelsey, SF1
Bittner, V1
Reis, SE1
Smith, K1
Braunstein, GD1
Berga, SL1
Johnson, BD1
Bairey Merz, CN1
Heal, DJ1
Silva, TC1
Barrett-Connor, E2
Ramires, JA1
Mansur, AP1
Laatikainen, T1
Tulenheimo, A1
Andersson, B1
Kärkkäinen, J1
Falsetti, L1
Omodei, U1
Dordoni, D1
Scagliola, P1
Turla, R1
Zotti, L1
Archetti, L1
Klinga, K2
von Holst, T2
Runnebaum, B2
Kley, HK4
Zimmermann, H1
Krüskemper, G1
Trichopoulos, D1
Polychronopoulou, A1
Brown, J1
MacMahon, B1
Lemon, HM2
Kirschner, MA3
Schneider, G3
Ertel, NH2
Worton, E1
de Waard, F1
Poortman, J1
de Pedro-Alvarez Ferrero, M1
Baanders-van Halewijn, EA1
Donaldson, JO2
Horak, E1
Binstock, ML1
Noel, CT1
Reed, MJ1
Jacobs, HS1
James, VH1
Ertel, N1
Kream, J1
O'Connor, J1
Levin, J1
Fukushima, DK1
Judd, HL2
Davidson, BJ1
Frumar, AM1
Shamonki, IM1
Lagasse, LD1
Ballon, SC1
Deselaers, T1
Peerenboom, H1
Krüskemper, HL3
Edelmann, P1
Kuller, LH4
Gutai, JP4
Kotarski, J1
Takemoto, M1
Morishita, H1
Higuchi, K1
Yoshida, J1
Aono, T1
Cauley, JA2
Scott, J1
Nevitt, MC1
Leenen, R1
van der Kooy, K1
Seidell, JC1
Deurenberg, P1
Koppeschaar, HP1
Sanchis, D4
Adán, C5
Ardévol, A1
Del Mar Grasa, M2
Balada, F5
Estruch, J8
Puerta, M1
Virgili, J5
Pérez-Clausell, J1
Masanés, RM2
Aguilar, H1
Masanés, R2
Tang, V1
Ferrer, E1
Torregrosa, C2
Campagnoli, C1
Ambroggio, S1
Biglia, N1
Sismondi, P1
Bullo, M1
García-Lorda, P1
Salas-Salvadó, J1
Stomati, M1
Monteleone, P1
Casarosa, E1
Quirici, B1
Puccetti, S1
Bernardi, F1
Genazzani, AD1
Rovati, L1
Luisi, M1
Genazzani, AR1
Guijarro, P1
López, J1
Ricci, TA2
Heymsfield, SB2
Pierson, RN2
Stahl, T2
Chowdhury, HA1
Shapses, SA2
Von Thun, NL1
Ospina, M1
Borthwick, EB1
Houston, MP1
Coughtrie, MW1
Burchell, A1
Van Dam, EW1
Roelfsema, F1
Veldhuis, JD1
Helmerhorst, FM1
Frölich, M1
Meinders, AE1
Krans, HM1
Pijl, H1
Peinado-Onsurbe, J2
Casadomé, L1
Daniell, HW1
Cole, P1
Cramer, D1
Schindler, AE2
Berkowitz, R1
Solbach, HG1
McKinnan, JC1
Edman, CD3
Aiman, EJ1
Porter, JC2
MacDonald, PC4
Hemsell, DL1
Siiteri, PK2
Vermeulen, A1
Verdonck, L1
Tomaszewska, H1
Niesluchowska, B1
Teter, J1
Knorr, D1
Bidlingmaier, F1
Lipsett, MB1
Rizkallah, TH1
Tovell, HM1
Kelly, WG1
Weiss, NS1
Szekely, DR1
Austin, DF1
Khaw, KT1
Mohan, PF1
Cleary, MP1
Mehta, RR1
Beattie, CW1
Das Gupta, TK1
Buyalos, RP1
Geffner, ME1
Bersch, N1
Watanabe, RM1
Bergman, RN1
Golde, DW1
Yoshida, S1
Inadera, H1
Ishikawa, Y1
Shinomiya, M1
Shirai, K1
Saito, Y1
Byrne, B1
Cunningham, S1
Igoe, D1
Conroy, R1
McKenna, TJ2
Nestler, JE1
Powers, LP1
Matt, DW1
Steingold, KA1
Plymate, SR1
Rittmaster, RS1
Clore, JN1
Blackard, WG1
Austin, H1
Austin, JM1
Partridge, EE1
Hatch, KD1
Shingleton, HM1
Brind, J1
Strain, G1
Miller, L1
Vogelman, J1
Orentreich, N1
Furuhashi, N1
Tsujiei, M1
LeDonne, D1
Powell, JG1
Soler, JT1
Folsom, AR1
Kaye, SA1
Prineas, RJ1
Dunaif, A1
Mandeli, J1
Fluhr, H1
Dobrjansky, A1
Rosner, W2
Levit, C1
Kalin, M1
Hershcopf, RJ1
Rosenfeld, RS2
Levit, CD1
Miller, EH1
Ortega, E1
Ruiz, E1
Osorio, C1
Prochazka, M1
Premdas, FH1
Leiter, EH1
Lipson, LG1
Begg, L1
Caggiula, AG1
Wolmark, N1
Watson, CG1
Schjeide, OA1
Prahlad, KV1
Kelley, JL1
Schjeide, SM1
Loughlin, T1
Cunningham, SK1
Culliton, M1
Smyth, PP1
Meagher, DJ1
Enriori, CL1
Orsini, W1
del Carmen Cremona, M1
Etkin, AE1
Cardillo, LR1
Reforzo-Membrives, J1
Johnston, CC1
Hui, SL1
Longcope, C1
Bleau, G1
Roberts, KD1
Chapdelaine, A1
Gläser, F1
Ebert, A1
Kurt, H1
Friedrich, E1
Bassett, M1
Meisel, D1
Kozu, T1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Women In Steady Exercise Research (WISER) Survivor Trial & Cost of Illness and Cost Effectiveness of Alternative Management Strategies[NCT01515124]450 participants (Actual)Interventional2012-01-31Completed
Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism[NCT03490513]Phase 4120 participants (Anticipated)Interventional2018-04-15Recruiting
Descriptive, Transversal Study of Evaluation of Cardiovascular Risks Factors and Prevalence of Metabolic Syndrome in the Different Phenotypes of Women With Polycystic Ovary Syndrome[NCT00784615]80 participants (Anticipated)Observational2007-12-31Recruiting
Clinical Metabolic and Endocrine Parameters in Response to Metformin and Lifestyle Intervention in Women With Polycystic Ovary Syndrome: A Phase 4 Randomized, Double- Blind and Placebo Control Trial[NCT00679679]Phase 430 participants (Actual)Interventional2003-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for estrone and Obesity

ArticleYear
Obesity, cholesterol, and clear-cell renal cell carcinoma (RCC).
    Advances in cancer research, 2010, Volume: 107

    Topics: Adiponectin; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Renal Cell; Carrier Proteins;

2010
Oleoyl-estrone.
    Medicinal research reviews, 2012, Volume: 32, Issue:6

    Topics: Animals; Energy Metabolism; Estrone; Humans; Insulin Resistance; Lipoproteins; Obesity; Oleic Acids;

2012
Pathophysiologic considerations in the treatment of menopausal patients with oestrogens; the role of oestriol in the prevention of mammary carcinoma.
    Acta endocrinologica. Supplementum, 1980, Volume: 233

    Topics: Adolescent; Adult; Aged; Animals; Breast Neoplasms; Estradiol; Estriol; Estrogens; Estrone; Female;

1980
Conjugated estrogens and breast cancer risk.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1999, Volume: 13 Suppl 6

    Topics: Adult; Aged; Breast Neoplasms; Estradiol; Estrogens, Conjugated (USP); Estrone; Female; Hormone Repl

1999
[Endometrial cancer and extraglandular oestrogen biosynthesis (author's transl)].
    Geburtshilfe und Frauenheilkunde, 1977, Volume: 37, Issue:3

    Topics: Adipose Tissue; Adult; Androstenedione; Endometrium; Epithelial Cells; Epithelium; Estradiol; Estrog

1977
Gynaecomastia in male adolescents.
    Clinics in endocrinology and metabolism, 1975, Volume: 4, Issue:1

    Topics: Adolescent; Diagnosis, Differential; Disorders of Sex Development; Estradiol; Estrogens; Estrone; Fo

1975
Hormones, nutrition, and cancer.
    Cancer research, 1975, Volume: 35, Issue:11 Pt. 2

    Topics: Androstenedione; Anovulation; Breast Neoplasms; Estrogens; Estrone; Female; Hormones; Humans; Neopla

1975
Endocrine influences on human mammary cancer formation. A critique.
    Cancer, 1969, Volume: 23, Issue:4

    Topics: Adrenocorticotropic Hormone; Androgens; Androsterone; Animals; Binding Sites; Breast Diseases; Breas

1969

Trials

10 trials available for estrone and Obesity

ArticleYear
Increased estrogen 2-hydroxylation in obese women using oral indole-3-carbinol.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1998, Volume: 22, Issue:3

    Topics: Administration, Oral; Adult; Antioxidants; Cohort Studies; Estradiol; Estriol; Estrogen Antagonists;

1998
Effects of vitamin D supplementation during weight loss on sex hormones in postmenopausal women.
    Menopause (New York, N.Y.), 2016, Volume: 23, Issue:6

    Topics: Aged; Cholecalciferol; Diet; Diet, Reducing; Dietary Supplements; Estradiol; Estrone; Exercise; Fema

2016
Reversal of the hypogonadotropic hypogonadism of obese men by administration of the aromatase inhibitor testolactone.
    Metabolism: clinical and experimental, 2003, Volume: 52, Issue:9

    Topics: Adult; Aromatase Inhibitors; Body Mass Index; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Foll

2003
Obese patients with polycystic ovary syndrome: evidence that metformin does not restore sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by ovarian steroids.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:11

    Topics: Adult; Androstenedione; Estrone; Feedback, Physiological; Female; Gonadal Steroid Hormones; Gonadotr

2003
Body mass index, circulating levels of sex-steroid hormones, IGF-I and IGF-binding protein-3: a cross-sectional study in healthy women.
    European journal of endocrinology, 2004, Volume: 150, Issue:2

    Topics: Adult; Aged; Androgens; Androstenedione; Body Mass Index; Case-Control Studies; Cohort Studies; Cros

2004
Obesity distribution and reproductive hormone levels in women: a report from the NHLBI-sponsored WISE Study.
    Journal of women's health (2002), 2006, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Body Mass Index; Cohort Studies; Coronary Artery Disease; Dyslipidem

2006
Effects of body weight on responses of serum prolactin to metoclopramide and thyrotrophin-releasing hormone in secondary amenorrhoeic women.
    Human reproduction (Oxford, England), 1994, Volume: 9, Issue:5

    Topics: Adult; Amenorrhea; Body Weight; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Humans; Lu

1994
Six-month oral dehydroepiandrosterone supplementation in early and late postmenopause.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2000, Volume: 14, Issue:5

    Topics: Administration, Oral; Adrenocorticotropic Hormone; Aged; Androgens; beta-Endorphin; Body Mass Index;

2000
Moderate energy restriction increases bone resorption in obese postmenopausal women.
    The American journal of clinical nutrition, 2001, Volume: 73, Issue:2

    Topics: Absorptiometry, Photon; Adipose Tissue; Body Composition; Bone Density; Bone Resorption; Diet, Reduc

2001
Bone turnover and density in obese premenopausal women during moderate weight loss and calcium supplementation.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, Volume: 16, Issue:7

    Topics: Absorptiometry, Photon; Adult; Amino Acids; Body Mass Index; Bone Density; Bone Resorption; Calcium,

2001

Other Studies

108 other studies available for estrone and Obesity

ArticleYear
Metabolomic analysis of serum from obese adults with hyperlipemia by UHPLC-Q-TOF MS/MS.
    Biomedical chromatography : BMC, 2016, Volume: 30, Issue:1

    Topics: Adult; Chromatography, High Pressure Liquid; Humans; Hydroxyestrones; Hyperlipidemias; Male; Metabol

2016
Augmenting Skeletal Muscle Estrogen Does not Prevent or Rescue Obesity-linked Metabolic Impairments in Female Mice.
    Endocrinology, 2022, 10-11, Volume: 163, Issue:11

    Topics: Animals; Aromatase; Diet, High-Fat; Estradiol; Estrogens; Estrone; Female; Glucose; Inflammation; In

2022
Testosterone and Estrone Increase From the Age of 70 Years: Findings From the Sex Hormones in Older Women Study.
    The Journal of clinical endocrinology and metabolism, 2019, 12-01, Volume: 104, Issue:12

    Topics: Aged; Aged, 80 and over; Aging; Biomarkers; Community-Based Participatory Research; Cross-Sectional

2019
A-FABP and oestrogens are independently involved in the development of breast cancer.
    Adipocyte, 2019, Volume: 8, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Comorbidity; Double-Blind Method; Estradiol; Estri

2019
Profound reduction of ovarian estrogen by aromatase inhibition in obese women.
    Obesity (Silver Spring, Md.), 2014, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Aromatase; Aromatase Inhibitors; Body Mass Index; Estrogens; Estrone; Female; Fol

2014
Complement receptors C5aR and C5L2 are associated with metabolic profile, sex hormones, and liver enzymes in obese women pre- and postbariatric surgery.
    Journal of obesity, 2014, Volume: 2014

    Topics: Adult; Age Factors; Aged; Animals; Apolipoproteins; Bariatric Surgery; Cholesterol, LDL; Complement

2014
Time-related increase in urinary testosterone levels and stable semen analysis parameters after bariatric surgery in men.
    Reproductive biomedicine online, 2015, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Estradiol; Estrogens; Estrone; Gastric Bypass; Humans; Infertility, Male; Male; O

2015
Vitamin D mitigates the adverse effects of obesity on breast cancer in mice.
    Endocrine-related cancer, 2016, Volume: 23, Issue:4

    Topics: Adiponectin; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Aromatase; Calcium; Cyclooxygen

2016
Treatment of pregnant rats with oleoyl-estrone slows down pup fat deposition after weaning.
    Reproductive biology and endocrinology : RB&E, 2008, Jun-20, Volume: 6

    Topics: Adipose Tissue; Age Factors; Animals; Anti-Obesity Agents; Body Composition; Eating; Energy Metaboli

2008
Maternal treatment with oleoyl-estrone induces resistance to lipid accrual in their descendants.
    Obesity (Silver Spring, Md.), 2008, Volume: 16, Issue:10

    Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Caloric Restriction; Dietar

2008
Influence of age and obesity on serum estradiol, estrone, and sex hormone binding globulin concentrations following oral estrogen administration in postmenopausal women.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:11

    Topics: Aged; Body Mass Index; Estradiol; Estrogens; Estrone; Female; Humans; Hysterectomy; Middle Aged; Obe

2009
Action profile of the antiobesity drug candidate oleoyl-estrone in rats.
    Obesity (Silver Spring, Md.), 2010, Volume: 18, Issue:12

    Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Arcuate Nucleus of Hypothalamus; Body Fluid Compartmen

2010
Age trends in estradiol and estrone levels measured using liquid chromatography tandem mass spectrometry in community-dwelling men of the Framingham Heart Study.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2013, Volume: 68, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Biomarkers; Body Mass Index; Boston; Cardio

2013
Weight loss reduces breast ductal fluid estrogens in obese postmenopausal women: a single arm intervention pilot study.
    Nutrition journal, 2012, Dec-05, Volume: 11

    Topics: Absorptiometry, Photon; Biomarkers; Body Composition; Body Mass Index; Diet; Diet, Reducing; Dietary

2012
Body composition modulates the effects of hormone replacement therapy on growth hormone and insulin-like growth factor-I levels in postmenopausal women.
    Gynecologic and obstetric investigation, 2002, Volume: 54, Issue:4

    Topics: Adipose Tissue; Adult; Aged; Body Composition; Body Constitution; Cross-Sectional Studies; Estradiol

2002
Plasma and urinary sex hormones are differently related to lipids in healthy postmenopausal women.
    Maturitas, 2003, Mar-28, Volume: 44, Issue:3

    Topics: Body Mass Index; Cholesterol, HDL; Cholesterol, VLDL; Cross-Sectional Studies; Estrone; Female; Gona

2003
Zucker obese rats store less acyl-estrone than lean controls.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2003, Volume: 27, Issue:4

    Topics: Adipose Tissue; Animals; Body Weight; Eating; Estrone; Female; Male; Obesity; Oleic Acids; Rats; Rat

2003
Adiposity and sex hormones in postmenopausal breast cancer survivors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, May-15, Volume: 21, Issue:10

    Topics: Absorptiometry, Photon; Adipose Tissue; Anthropometry; Body Mass Index; Breast Neoplasms; Cohort Stu

2003
Endometrial cancer, obesity, and estrogenic excretion in women.
    American journal of obstetrics and gynecology, 1961, Volume: 82

    Topics: Adenocarcinoma; Endometrial Neoplasms; Estrogens; Estrone; Female; Humans; Obesity; Uterine Neoplasm

1961
THE EFFECT OF NUTRITIONAL STATUS AND THYROID FUNCTION ON THE METABOLISM OF OESTRADIOL.
    The Journal of endocrinology, 1965, Volume: 32

    Topics: Estradiol; Estriol; Estrone; Geriatrics; Humans; Hyperthyroidism; Hypothyroidism; Metabolism; Nutrit

1965
When enough is too much: new strategies to treat obesity.
    Chemistry & biology, 2004, Volume: 11, Issue:8

    Topics: Drug Industry; Estrone; Humans; Obesity; Oleic Acids; Peptide Fragments; Peptide YY; Satiety Respons

2004
Oleoyl-estrone metabolic effects in relation with caloric restriction in inbred Beta rats with spontaneous obesity and type 2 diabetes.
    Medicina, 2004, Volume: 64, Issue:4

    Topics: Animals; Anti-Obesity Agents; Body Weight; Caloric Restriction; Cholesterol; Diabetes Mellitus, Type

2004
Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1

    Topics: 3T3 Cells; Adipocytes; Animals; Biotransformation; Blood Glucose; Cell Differentiation; Cholic Acids

2005
Effects of oleoyl-estrone with dexfenfluramine, sibutramine or phentermine on overweight rats.
    European journal of pharmacology, 2005, Apr-25, Volume: 513, Issue:3

    Topics: Animals; Anti-Obesity Agents; Body Weight; Cyclobutanes; Dexfenfluramine; Drug Interactions; Drug Th

2005
Strain variability in Zucker rats affects their response to oral oleoyl-estrone.
    Diabetes, nutrition & metabolism, 2004, Volume: 17, Issue:6

    Topics: Animals; Blood Glucose; Body Composition; Body Water; Cholesterol; Drinking; Eating; Energy Metaboli

2004
Combined effects of oleoyl-estrone and a beta3-adrenergic agonist (CL316,243) on lipid stores of diet-induced overweight male Wistar rats.
    Life sciences, 2005, Sep-02, Volume: 77, Issue:16

    Topics: 3-Hydroxybutyric Acid; Adrenergic beta-Agonists; Analysis of Variance; Animals; Blood Glucose; Dioxo

2005
A perspective on the hormonal abnormalities of obesity: are they cause or effect?
    Obesity research, 1994, Volume: 2, Issue:1

    Topics: Adolescent; Adult; beta-Endorphin; Estradiol; Estrone; Female; Gonadotropins; Hormones; Human Growth

1994
Combined effects of oral oleoyl-estrone and limited food intake on body composition of young overweight male rats.
    International journal of obesity (2005), 2006, Volume: 30, Issue:7

    Topics: Animals; Anti-Obesity Agents; Body Composition; Caloric Restriction; Combined Modality Therapy; Eati

2006
Weight loss with long-term intermittent treatment with oral oleoyl-estrone in lean Zucker male rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2006, Volume: 38, Issue:8

    Topics: Adipose Tissue; Administration, Oral; Animals; Anti-Obesity Agents; Body Composition; Body Weight; D

2006
Obesity drug development - CBI's 2nd Annual Summit.
    IDrugs : the investigational drugs journal, 2006, Volume: 9, Issue:10

    Topics: Adipocytes; Animals; Anti-Obesity Agents; Cannabinoid Receptor Modulators; Disease Models, Animal; D

2006
Effects of combined oleoyl-estrone and rimonabant on overweight rats.
    Journal of pharmacological sciences, 2007, Volume: 104, Issue:2

    Topics: Animals; Anti-Obesity Agents; Appetite; Blood Glucose; Cholecystokinin; Cholesterol; Drug Synergism;

2007
Obesity, estrone, and coronary artery disease in postmenopausal women.
    Maturitas, 2008, Mar-20, Volume: 59, Issue:3

    Topics: Aged; Aged, 80 and over; Body Mass Index; Coronary Artery Disease; Estrone; Female; Humans; Kaplan-M

2008
Obesity, serum steroid levels, and pulsatile gonadotropin secretion in polycystic ovarian disease.
    European journal of obstetrics, gynecology, and reproductive biology, 1983, Volume: 15, Issue:1

    Topics: Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Estrone;

1983
Profiles and endocrine correlations in endometrial carcinoma.
    European journal of gynaecological oncology, 1983, Volume: 4, Issue:1

    Topics: Age Factors; Aged; Androstenedione; Diabetes Complications; Estradiol; Estrone; Female; Follicle Sti

1983
Influence of severe obesity on peripheral hormone concentrations in pre- and postmenopausal women.
    European journal of obstetrics, gynecology, and reproductive biology, 1983, Volume: 15, Issue:2

    Topics: Adult; Androstenedione; Climacteric; Estrone; Female; Follicle Stimulating Hormone; Gonadal Steroid

1983
[Obesity and endocrine functions. Sex hormones].
    Deutsche medizinische Wochenschrift (1946), 1981, Sep-11, Volume: 106, Issue:37

    Topics: Androgens; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Human

1981
Serum concentrations of FSH, oestradiol, oestrone and androstenedione in normal and obese women.
    Maturitas, 1982, Volume: 4, Issue:1

    Topics: Adult; Aged; Androstenedione; Body Weight; Estradiol; Estrogens; Estrone; Female; Follicle Stimulati

1982
Obesity, serum cholesterol, and estrogens in premenopausal women.
    Oncology, 1983, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Aging; Body Weight; Cholesterol; Estradiol; Estriol; Estrogens; Estrone; Female;

1983
Obesity, androgens, estrogens, and cancer risk.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Androgens; Androstanols; Androstenedione; Body Weight; Estrogens; Estrone; Female; Humans; Male; Neo

1982
Relationship of obesity to blood estrogens.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Aromatase; Body Weight; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Male; Obesi

1982
Weight reduction and oestrogen excretion in obese post-menopausal women.
    Maturitas, 1982, Volume: 4, Issue:2

    Topics: Body Weight; Diet, Reducing; Estradiol; Estriol; Estrone; Female; Humans; Menopause; Middle Aged; Ob

1982
Cerebrospinal fluid oestrone in pseudotumour cerebri.
    Journal of neurology, neurosurgery, and psychiatry, 1982, Volume: 45, Issue:8

    Topics: Adult; Cerebrospinal Fluid Proteins; Dexamethasone; Diet, Reducing; Estradiol; Estriol; Estrone; Fem

1982
Pseudotumor cerebri in an obese woman with Turner syndrome.
    Neurology, 1981, Volume: 31, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Androstenedione; Estrogens; Estrone; Female; Humans; Menstruation; O

1981
The plasma concentration of oestrone sulphate in postmenopausal women: lack of diurnal variation, effect of ovariectomy, age and weight.
    Journal of steroid biochemistry, 1981, Volume: 14, Issue:11

    Topics: Aged; Aging; Castration; Circadian Rhythm; Estrone; Female; Humans; Male; Menopause; Middle Aged; Ob

1981
Obesity, hormones, and cancer.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 2

    Topics: Androgens; Androstenedione; Body Weight; Estrogens; Estrone; Female; Humans; Male; Menopause; Neopla

1981
Influence of obesity and malnutrition on the metabolism of some cancer-related hormones.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 2

    Topics: Anorexia Nervosa; Diet; Estradiol; Estrone; Female; Hormones; Humans; Male; Neoplasms; Nutrition Dis

1981
Obese young men have elevated plasma estrogen levels but obese premenopausal women do not.
    Metabolism: clinical and experimental, 1981, Volume: 30, Issue:10

    Topics: Adult; Age Factors; Estradiol; Estrone; Female; Humans; Male; Menopause; Menstruation; Middle Aged;

1981
Serum androgens and estrogens in postmenopausal women with and without endometrial cancer.
    American journal of obstetrics and gynecology, 1980, Apr-01, Volume: 136, Issue:7

    Topics: Adenocarcinoma; Age Factors; Aged; Androgens; Diabetes Complications; Estradiol; Estrogens; Estrone;

1980
Enhanced conversion of androstenedione to estrogens in obese males.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:5

    Topics: Adult; Androstenedione; Estradiol; Estrogens; Estrone; Humans; Male; Metabolic Clearance Rate; Obesi

1980
Relationship of plasma sex hormones to different parameters of obesity in male subjects.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:11

    Topics: Adult; Androgens; Androstenedione; Body Weight; Estradiol; Estrogens; Estrone; Humans; Male; Obesity

1980
Re: A prospective study of endogenous estrogens and breast cancer in postmenopausal women.
    Journal of the National Cancer Institute, 1995, Sep-20, Volume: 87, Issue:18

    Topics: Aged; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Middle Aged; Obesity; Postmen

1995
[Estrone concentration in endometrial cancer tissue in relation to body mass].
    Ginekologia polska, 1994, Volume: 65, Issue:9

    Topics: Aged; Aged, 80 and over; Body Mass Index; Endometrial Neoplasms; Estrone; Female; Humans; Middle Age

1994
Black-white differences in serum sex hormones and bone mineral density.
    American journal of epidemiology, 1994, May-15, Volume: 139, Issue:10

    Topics: Aged; Aged, 80 and over; Aging; Androstenedione; Black People; Bone Density; Estrone; Exercise; Fema

1994
Visceral fat accumulation in relation to sex hormones in obese men and women undergoing weight loss therapy.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 78, Issue:6

    Topics: Adipose Tissue; Adult; Androstenedione; Body Composition; Dehydroepiandrosterone; Dehydroepiandroste

1994
Short-term treatment with oleoyl-oestrone in liposomes (Merlin-2) strongly reduces the expression of the ob gene in young rats.
    The Biochemical journal, 1997, Sep-01, Volume: 326 ( Pt 2)

    Topics: Adipose Tissue; Animals; Drug Administration Schedule; Drug Carriers; Esters; Estrone; Female; Gene

1997
Effect of the slimming agent oleoyl-estrone in liposomes on the body weight of Zucker obese rats.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1997, Volume: 21, Issue:9

    Topics: Animals; Anti-Obesity Agents; Blood Glucose; Body Composition; Body Weight; Cholesterol; Cohort Stud

1997
Differential short-term distribution of estrone and oleoyl-estrone administered in liposomes to lean and obese Zucker rats.
    Obesity research, 1998, Volume: 6, Issue:1

    Topics: Adipose Tissue; Animals; Estrone; Female; Liposomes; Liver; Lung; Muscles; Obesity; Oleic Acids; Rat

1998
Effect of oleoyl-estrone administration on corticosterone binding to tissues of lean and obese Zucker rats.
    The Journal of steroid biochemistry and molecular biology, 1998, Volume: 66, Issue:3

    Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Blotting, Northern; Body Weight; Corticosterone; Estro

1998
Zucker obese rats are insensitive to the CRH-increasing effect of oleoyl-estrone.
    Brain research bulletin, 1998, Volume: 46, Issue:6

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Obesity Agents; Appetite; Corticosterone; Corticotropin-R

1998
Oleoyl-estrone does not alter hypothalamic neuropeptide Y in Zucker lean and obese rats.
    Peptides, 1998, Volume: 19, Issue:9

    Topics: Animals; Anti-Obesity Agents; Body Weight; Eating; Energy Metabolism; Estrone; Female; Hypothalamus;

1998
Oleoyl-estrone treatment affects the ponderostat setting differently in lean and obese Zucker rats.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1999, Volume: 23, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Energy Intake

1999
Leptin enhances the synthesis of oleoyl-estrone from estrone in white adipose tissue.
    European journal of nutrition, 1999, Volume: 38, Issue:2

    Topics: 3T3 Cells; Adipose Tissue; Adipose Tissue, Brown; Animals; Chromatography, High Pressure Liquid; Chr

1999
Short-term treatment with estrone oleate in liposomes (Merlin-2) does not affect the expression of the ob gene in Zucker obese rats.
    Molecular and cellular biochemistry, 1999, Volume: 197, Issue:1-2

    Topics: Animals; Blood Glucose; Carrier Proteins; Corticosterone; Estrone; Female; Gene Expression Regulatio

1999
Estrone in food: a factor influencing the development of obesity?
    European journal of nutrition, 1999, Volume: 38, Issue:5

    Topics: Animals; Body Mass Index; Energy Metabolism; Estrone; Female; Food Analysis; Humans; Obesity; Rats;

1999
Plasma acyl-estrone levels are altered in obese women.
    Endocrine research, 2000, Volume: 26, Issue:3

    Topics: Acylation; Adipose Tissue; Adult; Aspartate Aminotransferases; Blood Glucose; Body Composition; Body

2000
Oral oleoyl-estrone induces the rapid loss of body fat in Zucker lean rats fed a hyperlipidic diet.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2000, Volume: 24, Issue:11

    Topics: Adipose Tissue; Administration, Oral; Amino Acids; Animals; Anti-Obesity Agents; Body Composition; B

2000
The antihyperglycemic effect of estrone sulfate in genetically obese-diabetic (ob/ob) mice is associated with reduced hepatic glucose-6-phosphatase.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2001, Volume: 33, Issue:12

    Topics: Aging; Animals; Blood Glucose; Dehydroepiandrosterone Sulfate; Diabetes Mellitus; Estradiol; Estrone

2001
Increase in daily LH secretion in response to short-term calorie restriction in obese women with PCOS.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:4

    Topics: Adult; Androstenedione; Blood Glucose; Body Mass Index; Diet, Reducing; Energy Intake; Estradiol; Es

2002
Effect of 24-h food deprivation on lipoprotein composition and oleoyl-estrone content of lean and obese Zucker rats.
    European journal of nutrition, 2001, Volume: 40, Issue:4

    Topics: Adipose Tissue; Animals; Blood Proteins; Chylomicrons; Estrone; Female; Food Deprivation; Hyperlipid

2001
Effect of oral oleoyl-estrone treatment on plasma lipoproteins and tissue lipase activities of Zucker lean and obese female rats.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2002, Volume: 26, Issue:5

    Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Cholesterol; Cholesterol, HDL; Estrone; Female; Lipase

2002
Smoking, obesity, and the menopause.
    Lancet (London, England), 1978, Aug-12, Volume: 2, Issue:8085

    Topics: Adult; Age Factors; Aged; Estrone; Female; Humans; Menopause; Middle Aged; Obesity; Smoking

1978
Diet and cancer of endocrine target organs.
    Cancer, 1977, Volume: 40, Issue:1 Suppl

    Topics: Adult; Age Factors; Aged; Boston; Breast Neoplasms; Diet; Estrogens; Estrogens, Conjugated (USP); Es

1977
Increased estrogen production in obese men.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 48, Issue:4

    Topics: Body Weight; Clomiphene; Estradiol; Estrone; Follicle Stimulating Hormone; Humans; Hypothalamo-Hypop

1979
Testosterone decrease and oestrogen increase in male patients with obesity.
    Acta endocrinologica, 1979, Volume: 91, Issue:3

    Topics: Adult; Androstenedione; Chorionic Gonadotropin; Estradiol; Estrogens; Estrone; Humans; Hydrocortison

1979
Identification of the estrogen product of extraglandular aromatization of plasma androstenedione.
    American journal of obstetrics and gynecology, 1978, Feb-15, Volume: 130, Issue:4

    Topics: Adolescent; Adult; Androstenedione; Chemical Phenomena; Chemistry; Estradiol; Estriol; Estrogens; Es

1978
Effect of obesity on conversion of plasma androstenedione to estrone in postmenopausal women with and without endometrial cancer.
    American journal of obstetrics and gynecology, 1978, Feb-15, Volume: 130, Issue:4

    Topics: Adenocarcinoma; Aged; Aging; Androstenedione; Estrogens; Estrone; Female; Humans; Menopause; Middle

1978
Effect of obesity on conversion of plasma androstenedione to estrone in ovulatory and anovulator young women.
    American journal of obstetrics and gynecology, 1978, Feb-15, Volume: 130, Issue:4

    Topics: Adolescent; Adult; Androstenedione; Anovulation; Estrone; Female; Humans; Obesity; Ovulation

1978
Sex hormone concentrations in post-menopausal women.
    Clinical endocrinology, 1978, Volume: 9, Issue:1

    Topics: Age Factors; Aged; Androstenedione; Estradiol; Estrone; Female; Humans; Menopause; Middle Aged; Obes

1978
[Uncommonly high concentration of estrone of adrenal origin in a case of androgenic obesity, anovulation and amenorrhea].
    Ginekologia polska, 1977, Volume: 48, Issue:8

    Topics: Adrenal Glands; Adult; Amenorrhea; Androgens; Anovulation; Diabetes Mellitus; Estrone; Female; Hirsu

1977
Production of estrone and fractional conversion of circulating androstenedione to estrone in women with endometrial carcinoma.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Androstenedione; Body Height; Body Weight; Endometrium; Estriol; Estrog

1975
Increasing incidence of endometrial cancer in the United States.
    The New England journal of medicine, 1976, Jun-03, Volume: 294, Issue:23

    Topics: Adenocarcinoma; Adult; Age Factors; Aged; Androstenedione; Contraceptives, Oral; Estrogens; Estrone;

1976
Lower endogenous androgens predict central adiposity in men.
    Annals of epidemiology, 1992, Volume: 2, Issue:5

    Topics: Adult; Aged; Androgens; Androstenedione; Body Constitution; Body Mass Index; Cardiovascular Diseases

1992
Studies on nuclear binding of dehydroepiandrosterone in hepatocytes.
    Steroids, 1992, Volume: 57, Issue:5

    Topics: Animals; Cell Nucleus; Corticosterone; Dehydroepiandrosterone; Estrone; Female; Liver; Obesity; Rats

1992
Endocrine profile in breast cancer patients receiving chemotherapy.
    Breast cancer research and treatment, 1992, Volume: 20, Issue:2

    Topics: Adult; Age Factors; Amenorrhea; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Bre

1992
Insulin and insulin-like growth factor-I responsiveness in polycystic ovarian syndrome.
    Fertility and sterility, 1992, Volume: 57, Issue:4

    Topics: Adult; Analysis of Variance; Androgens; Cell Line, Transformed; Colony-Forming Units Assay; Estradio

1992
Endocrine disorders and body fat distribution.
    International journal of obesity, 1991, Volume: 15 Suppl 2

    Topics: Acromegaly; Adipose Tissue; Animals; Cushing Syndrome; Endocrine System Diseases; Estrogens; Estrone

1991
Sex steroids, adiposity and smoking in the pathogenesis of idiopathic hirsutism and polycystic ovary syndrome.
    Acta endocrinologica, 1991, Volume: 124, Issue:4

    Topics: Adrenal Glands; Adult; Androgens; Androstenedione; Body Mass Index; Body Weight; Dehydroepiandroster

1991
A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:1

    Topics: Adult; Androstane-3,17-diol; Androstenedione; Diazoxide; Estradiol; Estrone; Female; Glucose Toleran

1991
A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:1

    Topics: Adult; Androstane-3,17-diol; Androstenedione; Diazoxide; Estradiol; Estrone; Female; Glucose Toleran

1991
A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:1

    Topics: Adult; Androstane-3,17-diol; Androstenedione; Diazoxide; Estradiol; Estrone; Female; Glucose Toleran

1991
A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:1

    Topics: Adult; Androstane-3,17-diol; Androstenedione; Diazoxide; Estradiol; Estrone; Female; Glucose Toleran

1991
Endometrial cancer, obesity, and body fat distribution.
    Cancer research, 1991, Jan-15, Volume: 51, Issue:2

    Topics: Adipose Tissue; Adult; Aged; Androstenedione; Body Mass Index; Case-Control Studies; Estradiol; Estr

1991
Obese men have elevated plasma levels of estrone sulfate.
    International journal of obesity, 1990, Volume: 14, Issue:6

    Topics: Adipose Tissue; Adult; Androstenedione; Estrogens; Estrone; Humans; Male; Middle Aged; Obesity

1990
[Clinical significance of serum estrone analysis in endocrine tests of the gonadal and placental system].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 48 Suppl

    Topics: Adolescent; Adult; Aging; Endometriosis; Estrone; Female; Humans; Male; Obesity; Polycystic Ovary Sy

1989
The epidemiology of serum sex hormones in postmenopausal women.
    American journal of epidemiology, 1989, Volume: 129, Issue:6

    Topics: Aged; Alcohol Drinking; Androstenedione; Estradiol; Estrone; Exercise; Female; Gonadal Steroid Hormo

1989
Associations of abdominal adiposity, fasting insulin, sex hormone binding globulin, and estrone with lipids and lipoproteins in post-menopausal women.
    Atherosclerosis, 1989, Volume: 79, Issue:1

    Topics: Abdomen; Adipose Tissue; Aged; Androgens; Apolipoproteins A; Apolipoproteins B; Cholesterol, HDL; Es

1989
The impact of obesity and chronic hyperinsulinemia on gonadotropin release and gonadal steroid secretion in the polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradio

1988
Effect of massive weight loss on hypothalamic-pituitary-gonadal function in obese men.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 66, Issue:5

    Topics: Adult; Body Weight; Estradiol; Estrone; Follicle Stimulating Hormone; Humans; Hypothalamo-Hypophysea

1988
Partial reversal of the hypogonadotropic hypogonadism of obese men by administration of corticosuppressive doses of dexamethasone.
    International journal of obesity, 1988, Volume: 12, Issue:6

    Topics: Adult; Androstenedione; Dexamethasone; Estradiol; Estrone; Follicle Stimulating Hormone; Humans; Hyp

1988
[Effects of age and obesity on the conversion of androstenedione to estrone in postmenopausal women].
    Revista espanola de fisiologia, 1988, Volume: 44, Issue:1

    Topics: Aging; Androstenedione; Estrone; Female; Humans; Menopause; Obesity

1988
Estrone treatment dissociates primary versus secondary consequences of "diabetes" (db) gene expression in mice.
    Diabetes, 1986, Volume: 35, Issue:6

    Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Eating; Estrone; Female; Gene Expressio

1986
Endogenous sex hormone levels and breast cancer risk.
    Genetic epidemiology, 1987, Volume: 4, Issue:4

    Topics: Aged; Aged, 80 and over; Breast Neoplasms; Cholesterol; Cholesterol, HDL; Estradiol; Estrone; Female

1987
Serum lipids and lipoproteins in hypothyroidism.
    Cytobios, 1986, Volume: 48, Issue:192

    Topics: Animals; Body Weight; Chickens; Estrone; Fatty Acids; Hypothyroidism; Lipids; Lipoproteins; Obesity;

1986
Altered androstenedione and estrone dynamics associated with abnormal hormonal profiles in amenorrheic subjects with weight loss or obesity.
    Fertility and sterility, 1985, Volume: 43, Issue:5

    Topics: Adolescent; Adult; Amenorrhea; Androstenedione; Body Weight; Estradiol; Estrone; Female; Gonadotropi

1985
Decrease of circulating level of SHBG in postmenopausal obese women as a risk factor in breast cancer: reversible effect of weight loss.
    Gynecologic oncology, 1986, Volume: 23, Issue:1

    Topics: Aged; Androstenedione; Body Weight; Breast Neoplasms; Estradiol; Estrone; Female; Humans; Hydrocorti

1986
Bone mass and sex steroid concentrations in postmenopausal Caucasian diabetics.
    Metabolism: clinical and experimental, 1985, Volume: 34, Issue:6

    Topics: Aged; Bone and Bones; Diabetes Mellitus; Diabetes Mellitus, Type 2; Estrone; Female; Gonadal Steroid

1985
The in vitro and in vivo uptake and metabolism of steroids in human adipose tissue.
    The Journal of clinical endocrinology and metabolism, 1974, Volume: 39, Issue:2

    Topics: Adipose Tissue; Adult; Androstenedione; Animals; Carbon Radioisotopes; Culture Techniques; Dogs; Est

1974
The relationship between the extraglandular production of estrone and the occurrence of endometrial neoplasia.
    Gynecologic oncology, 1974, Volume: 2, Issue:2-3

    Topics: Adenocarcinoma; Adult; Age Factors; Aged; Androstenedione; Endometrium; Estrone; Female; Humans; Men

1974
[Proceedings: Etiology of corpus carcinoma].
    Archiv fur Gynakologie, 1973, Sep-28, Volume: 214, Issue:1

    Topics: Adipose Tissue; Androstenedione; Diabetes Complications; Estradiol; Estrone; Female; Humans; Hyperte

1973
Estrogen storage in fat.
    American journal of obstetrics and gynecology, 1967, Nov-15, Volume: 99, Issue:6

    Topics: Adipose Tissue; Animals; Carbon Isotopes; Endometrium; Estradiol; Estriol; Estrone; Estrus; Female;

1967
[Sex cycle and the absorption rate of H3-estrogen in obese animals].
    Nihon Sanka Fujinka Gakkai zasshi, 1969, Volume: 21, Issue:1

    Topics: Animals; Estradiol; Estrone; Estrus; Female; Liver; Mice; Obesity; Organ Size; Pregnancy; Tritium; U

1969