Page last updated: 2024-11-07

estrone and Melanoma

estrone has been researched along with Melanoma in 4 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
" estrone, 17-beta-estradiol and estriol, was studied in a melanoma cell line producing a tissue-type plasminogen activator (t-PA)."3.67Estrogen regulation of tissue plasminogen activator in a human melanoma cell line. ( Astedt, B; Kjaeldgaard, A; Larsson, B, 1986)
"The invasion of melanoma is complex and multi-staged and involves changes in both cell/extracellular matrix (ECM) and cell/cell interactions."1.31Oestrogenic steroids and melanoma cell interaction with adjacent skin cells influence invasion of melanoma cells in vitro. ( Eves, P; Ghanem, G; Layton, C; Lorigan, P; Molife, R; Morandini, R; Neil, SM; Richardson, B; Wagner, M, 2000)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miller, JG1
Gee, J1
Price, A1
Garbe, C1
Wagner, M2
Mac Neil, S1
Neil, SM1
Eves, P1
Richardson, B1
Molife, R1
Lorigan, P1
Layton, C1
Morandini, R1
Ghanem, G1
Kjaeldgaard, A1
Larsson, B1
Astedt, B1
Santen, RJ1
Santner, SJ1
Harvey, HA1
Lipton, A1
Simmonds, M1
Feil, PD1
Manders, E1
Davis, TS1

Other Studies

4 other studies available for estrone and Melanoma

ArticleYear
Investigation of oestrogen receptors, sex steroids and soluble adhesion molecules in the progression of malignant melanoma.
    Melanoma research, 1997, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Androstenedione; Cell Adhesion Molecules; Child; Disease

1997
Oestrogenic steroids and melanoma cell interaction with adjacent skin cells influence invasion of melanoma cells in vitro.
    Pigment cell research, 2000, Volume: 13 Suppl 8

    Topics: alpha-MSH; Estradiol; Estrone; Female; Humans; Melanoma; Neoplasm Invasiveness; Skin; Tumor Cells, C

2000
Estrogen regulation of tissue plasminogen activator in a human melanoma cell line.
    Thrombosis research, 1986, May-01, Volume: 42, Issue:3

    Topics: Cell Line; Depression, Chemical; Dose-Response Relationship, Drug; Estradiol; Estriol; Estrogens; Es

1986
Marked heterogeneity of aromatase activity in human malignant melanoma tissue.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:12

    Topics: Adult; Aged; Aminoglutethimide; Aromatase; Aromatase Inhibitors; Biomarkers, Tumor; Estradiol; Estro

1988