estrone has been researched along with Long Sleeper Syndrome in 6 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to describe the changes in symptom interference during the menopausal transition (MT) stages and early postmenopause (PM), including the effects of age, MT-related factors (estrone, follicle-stimulating hormone, testosterone, MT stages), symptoms (hot flashes, depressed mood, awakening during the night, anxiety, backache, joint pain, forgetfulness, and difficulty concentrating), health-related factors (perceived health), and stress-related factors (perceived stress, cortisol)." | 3.77 | Symptom interference with work and relationships during the menopausal transition and early postmenopause: observations from the Seattle Midlife Women's Health Study. ( Mitchell, ES; Woods, NF, 2011) |
| "To determine whether hot flashes, depressed mood, sleep, cognitive and sexual symptoms correlate with urinary follicle-stimulating hormone (FSH), estrone (E(1)G), and testosterone (T) and with each other during the menopausal transition and early postmenopause (PM)." | 3.74 | Symptoms during the menopausal transition and early postmenopause and their relation to endocrine levels over time: observations from the Seattle Midlife Women's Health Study. ( Mitchell, ES; Percival, DB; Smith-Dijulio, K; Tao, EY; Taylor, HJ; Woods, NF, 2007) |
| "We recruited 177 post-menopausal women to register hot flashes, vaginal dryness, depression, anxiety, sleep alterations, and serum hormones (FSH, LH, estrone, and estradiol)." | 3.72 | The relationship of estrogen receptor-alpha polymorphism with symptoms and other characteristics in post-menopausal women. ( Malacara, JM; Martínez-Garza, S; Pérez-Luque, EL; Sánchez-Marín, FJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joffe, H | 1 |
| Crawford, S | 1 |
| Economou, N | 1 |
| Kim, S | 1 |
| Regan, S | 1 |
| Hall, JE | 1 |
| White, D | 1 |
| Woods, NF | 3 |
| Cray, L | 1 |
| Mitchell, ES | 3 |
| Herting, JR | 1 |
| Kische, H | 1 |
| Ewert, R | 1 |
| Fietze, I | 1 |
| Gross, S | 1 |
| Wallaschofski, H | 1 |
| Völzke, H | 1 |
| Dörr, M | 1 |
| Nauck, M | 1 |
| Obst, A | 1 |
| Stubbe, B | 1 |
| Penzel, T | 1 |
| Haring, R | 1 |
| Malacara, JM | 1 |
| Pérez-Luque, EL | 1 |
| Martínez-Garza, S | 1 |
| Sánchez-Marín, FJ | 1 |
| Smith-Dijulio, K | 1 |
| Percival, DB | 1 |
| Tao, EY | 1 |
| Taylor, HJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Experimentally Induced Hot Flashes on Sleep and Mood Disturbance[NCT01116401] | Phase 4 | 29 participants (Actual) | Interventional | 2009-11-03 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The Montgomery-Åsberg Depression Rating Scale is a widely used 10-item clinician-rated scale that describes the severity of depressive symptoms. It has a range of 0-60 with higher scores indicating greater symptom burden. Participants were assessed at baseline and four weeks after the GnRHa injection in order to calculate the change in MADRS score. (NCT01116401)
Timeframe: baseline and 4 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| GnRH Agonist Injection | 3.1 |
Wake after sleep onset (WASO) is calculated by averaging the number of minutes spent awake after initiating sleep each night from the two ambulatory polysomnography studies conducted at baseline and the two ambulatory polysomnography studies conducted four weeks after the GnRHa injection. (NCT01116401)
Timeframe: baseline and 4 weeks
| Intervention | percent change (Number) |
|---|---|
| GnRH Agonist Injection | 62 |
6 other studies available for estrone and Long Sleeper Syndrome
| Article | Year |
|---|---|
A gonadotropin-releasing hormone agonist model demonstrates that nocturnal hot flashes interrupt objective sleep.
Topics: Adolescent; Adult; Circadian Rhythm; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Gonad | 2013 |
Endocrine biomarkers and symptom clusters during the menopausal transition and early postmenopause: observations from the Seattle Midlife Women's Health Study.
Topics: Adult; Affective Symptoms; Autonomic Nervous System; Cognition Disorders; Estrone; Female; Follicle | 2014 |
Sex Hormones and Sleep in Men and Women From the General Population: A Cross-Sectional Observational Study.
Topics: Adult; Age Factors; Algorithms; Androstenedione; Cohort Studies; Cross-Sectional Studies; Dehydroepi | 2016 |
Symptom interference with work and relationships during the menopausal transition and early postmenopause: observations from the Seattle Midlife Women's Health Study.
Topics: Adult; Anxiety; Biomarkers; Comorbidity; Depression; Estrone; Female; Follicle Stimulating Hormone, | 2011 |
The relationship of estrogen receptor-alpha polymorphism with symptoms and other characteristics in post-menopausal women.
Topics: Anxiety; Bone Density; Cross-Sectional Studies; Depression; Educational Status; Estradiol; Estrogen | 2004 |
Symptoms during the menopausal transition and early postmenopause and their relation to endocrine levels over time: observations from the Seattle Midlife Women's Health Study.
Topics: Adult; Anxiety; Biomarkers; Depression; Estrone; Female; Follicle Stimulating Hormone, Human; Health | 2007 |