Page last updated: 2024-11-07

estrone and Local Neoplasm Recurrence

estrone has been researched along with Local Neoplasm Recurrence in 11 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy, safety and tolerability of letrozole, an advanced non-steroidal aromatase inhibitor, and fadrozole hydrochloride, an older-generation drug in this class, we conducted a randomised double-blind trial in postmenopausal women with advanced breast cancer."9.10Double-blind randomised trial comparing the non-steroidal aromatase inhibitors letrozole and fadrozole in postmenopausal women with advanced breast cancer. ( Adachi, I; Ikeda, T; Ohashi, Y; Sasaki, Y; Suwa, T; Tabei, T; Takatsuka, Y; Toi, M; Tominaga, T, 2003)
"About one third of unselected postmenopausal women with advanced breast cancer respond to treatment with aminoglutethimide and hydrocortisone, but they all eventually relapse, and further progression of disease occurs."7.67Endocrine changes associated with relapse in advanced breast cancer patients on aminoglutethimide therapy. ( Dowsett, M; Harris, AL; Jeffcoate, SL; Smith, IE, 1984)
" While this regimen effectively blocked adrenal function, it was complicated by a drug interaction in which aminoglutethimide accelerated the metabolism and reduced the bioavailability of dexamethasone."6.36Kinetic, hormonal and clinical studies with aminoglutethimide in breast cancer. ( Harvey, H; Kendall, J; Lipton, A; Ruby, EB; Samojlik, E; Santen, RJ; Wells, SA, 1977)
"To compare the efficacy, safety and tolerability of letrozole, an advanced non-steroidal aromatase inhibitor, and fadrozole hydrochloride, an older-generation drug in this class, we conducted a randomised double-blind trial in postmenopausal women with advanced breast cancer."5.10Double-blind randomised trial comparing the non-steroidal aromatase inhibitors letrozole and fadrozole in postmenopausal women with advanced breast cancer. ( Adachi, I; Ikeda, T; Ohashi, Y; Sasaki, Y; Suwa, T; Tabei, T; Takatsuka, Y; Toi, M; Tominaga, T, 2003)
"About one third of unselected postmenopausal women with advanced breast cancer respond to treatment with aminoglutethimide and hydrocortisone, but they all eventually relapse, and further progression of disease occurs."3.67Endocrine changes associated with relapse in advanced breast cancer patients on aminoglutethimide therapy. ( Dowsett, M; Harris, AL; Jeffcoate, SL; Smith, IE, 1984)
" While this regimen effectively blocked adrenal function, it was complicated by a drug interaction in which aminoglutethimide accelerated the metabolism and reduced the bioavailability of dexamethasone."2.36Kinetic, hormonal and clinical studies with aminoglutethimide in breast cancer. ( Harvey, H; Kendall, J; Lipton, A; Ruby, EB; Samojlik, E; Santen, RJ; Wells, SA, 1977)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's1 (9.09)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Matei, D1
Schilder, J1
Sutton, G1
Perkins, S1
Breen, T1
Quon, C1
Sidor, C1
Slomovitz, BM1
Filiaci, VL1
Walker, JL1
Taub, MC1
Finkelstein, KA1
Moroney, JW1
Fleury, AC1
Muller, CY1
Holman, LL1
Copeland, LJ1
Miller, DS1
Coleman, RL1
Ingle, JN1
Kalari, KR1
Barman, P1
Shepherd, LE1
Ellis, MJ1
Goss, PE1
Buzdar, AU1
Robson, ME1
Cairns, J1
Carlson, EE1
Eyman Casey, A1
Hoskin, TL1
Goodnature, BA1
Haddad, TC1
Goetz, MP1
Weinshilboum, RM1
Wang, L1
Tominaga, T1
Adachi, I1
Sasaki, Y1
Tabei, T1
Ikeda, T1
Takatsuka, Y1
Toi, M1
Suwa, T1
Ohashi, Y1
Dowsett, M1
Harris, AL1
Smith, IE1
Jeffcoate, SL1
Jalůvka, V1
Kratzsch, E1
Bonte, J1
Ide, P1
Billiet, G1
Wynants, P1
Wada, T1
Nomura, Y1
Oohashi, Y1
Abe, O1
Koyama, H1
Takashima, S1
Santen, RJ1
Samojlik, E1
Lipton, A1
Harvey, H1
Ruby, EB1
Wells, SA1
Kendall, J1
Kalavathi, N1
Grönroos, M1
Aho, AJ1

Reviews

2 reviews available for estrone and Local Neoplasm Recurrence

ArticleYear
[Hormone activity of various Brenner tumors].
    Gynakologische Rundschau, 1982, Volume: 22, Issue:1

    Topics: Aged; Breast Neoplasms; Brenner Tumor; Estradiol; Estrone; Female; Humans; Neoplasm Metastasis; Neop

1982
Kinetic, hormonal and clinical studies with aminoglutethimide in breast cancer.
    Cancer, 1977, Volume: 39, Issue:6 Suppl

    Topics: Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehy

1977

Trials

4 trials available for estrone and Local Neoplasm Recurrence

ArticleYear
Activity of 2 methoxyestradiol (Panzem NCD) in advanced, platinum-resistant ovarian cancer and primary peritoneal carcinomatosis: a Hoosier Oncology Group trial.
    Gynecologic oncology, 2009, Volume: 115, Issue:1

    Topics: 2-Methoxyestradiol; Adult; Aged; Antineoplastic Agents; CA-125 Antigen; Disease-Free Survival; Drug

2009
A randomized phase II trial of everolimus and letrozole or hormonal therapy in women with advanced, persistent or recurrent endometrial carcinoma: A GOG Foundation study.
    Gynecologic oncology, 2022, Volume: 164, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Combinations; Endometrial Neoplasms; Estradiol;

2022
Double-blind randomised trial comparing the non-steroidal aromatase inhibitors letrozole and fadrozole in postmenopausal women with advanced breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:1

    Topics: Administration, Oral; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease Progres

2003
[Late phase II study of CGS16949A, a new aromatase inhibitor--a multicentral cooperative study (Western Japan Group)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1994, Volume: 21, Issue:4

    Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Drug Administration Schedule; Estradiol; Estron

1994

Other Studies

5 other studies available for estrone and Local Neoplasm Recurrence

ArticleYear
Single-nucleotide polymorphism biomarkers of adjuvant anastrozole-induced estrogen suppression in early breast cancer.
    Pharmacogenetics and genomics, 2021, Volume: 31, Issue:1

    Topics: Adult; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrone; Female; Genetic Pred

2021
Endocrine changes associated with relapse in advanced breast cancer patients on aminoglutethimide therapy.
    The Journal of clinical endocrinology and metabolism, 1984, Volume: 58, Issue:1

    Topics: Aminoglutethimide; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Fe

1984
Tamoxifen as a possible chemotherapeutic agent in endometrial adenocarcinoma.
    Gynecologic oncology, 1981, Volume: 11, Issue:2

    Topics: Adenocarcinoma; Cells, Cultured; Estrone; Female; Follicle Stimulating Hormone; Humans; Luteinizing

1981
Granulosa cell tumour--hormonal aspects and radiosensitivity.
    Clinical radiology, 1971, Volume: 22, Issue:4

    Topics: Abdominal Neoplasms; Adult; Aged; Estradiol; Estriol; Estrogens; Estrone; Female; Gold Isotopes; Gon

1971
Estrogen metabolism in postmenopausal women with primary and recurrent breast cancer.
    European journal of cancer, 1968, Volume: 4, Issue:5

    Topics: Aging; Breast Neoplasms; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Menopause; Middle A

1968
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