estrone has been researched along with Liver Neoplasms in 31 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A group of 122 postmenopausal patients with histologically proven node-positive primary breast cancer have been randomized to receive aminoglutethimide-hydrocortisone or placebo aminoglutethimide-placebo hydrocortisone for 2 years." | 9.05 | Adjuvant aminoglutethimide therapy for postmenopausal patients with primary breast cancer: progress report. ( Bettelheim, R; Chilvers, C; Coombes, RC; Dowsett, M; Ford, HT; Gazet, JC; Gordon, C; Powles, TJ; Smith, IE; Zava, D, 1982) |
| "A group of 122 postmenopausal patients with histologically proven node-positive primary breast cancer have been randomized to receive aminoglutethimide-hydrocortisone or placebo aminoglutethimide-placebo hydrocortisone for 2 years." | 5.05 | Adjuvant aminoglutethimide therapy for postmenopausal patients with primary breast cancer: progress report. ( Bettelheim, R; Chilvers, C; Coombes, RC; Dowsett, M; Ford, HT; Gazet, JC; Gordon, C; Powles, TJ; Smith, IE; Zava, D, 1982) |
| "This report represents the first study in the literature linking development of severe gynecomastia, in a 17 1/2-yr-old boy, to high levels of aromatase expression in a large fibrolamellar hepatocellular carcinoma, which gave rise to extremely elevated serum levels of estrone (1200 pg/mL) and estradiol-17 beta (312 pg/mL) that suppressed FSH and LH (1." | 3.70 | Molecular basis of severe gynecomastia associated with aromatase expression in a fibrolamellar hepatocellular carcinoma. ( Agarwal, VR; Bulun, SE; Sasano, H; Simpson, ER; Takayama, K; Van Wyk, JJ, 1998) |
| "To investigate the possible role of sex-hormone imbalance in hepatocellular carcinogenesis in male alcoholic cirrhotic patients, we determined plasma levels of testosterone (T), dihydrotestosterone (DHT), androstenedione (A), dehydroepiandrosterone (DHA), estrone (E1), estradiol (E2), and sex-hormone-binding globulin (SHBG) in 15 men with alcoholic cirrhosis alone and in 15 similar men with alcoholic cirrhosis and hepatocellular carcinoma (HCC)." | 3.67 | Sex hormone imbalance in male alcoholic cirrhotic patients with and without hepatocellular carcinoma. ( Ballet, F; Giboudeau, J; Guéchot, J; Peigney, N; Poupon, R; Vaubourdolle, M, 1988) |
| "A total of 12,312 non-surgical liver cancer patients were enrolled in this study." | 1.62 | Estradiol is significantly associated with prognosis in non-surgical liver cancer patients: from bench to bedside. ( Fan, J; Li, C; Liu, Y; Sun, H; Wang, R; Wang, T; Wang, Z, 2021) |
| "Estrone was significantly elevated in both groups of patients." | 1.27 | Serum levels of estrogens and testosterone in cirrhotic men with and without hepatocellular carcinoma. ( Ito, A; Nagasue, N; Ogawa, Y; Ohta, N; Yukaya, H, 1985) |
| "Primary liver cancer occasionally presents with feminization." | 1.26 | Mechanism of feminization in primary liver cancer. ( Abrahams, GE; Katz, M; Kew, MC; Kirschner, MA, 1977) |
| "Liver metastases of hormone-dependent adrenal carcinomas continued growth and could not be influenced by removal of estrogen, although the primary transplant regressed." | 1.26 | Hormonal control of growth and progression in tumors of Nb rats and a theory of action. ( Noble, RL, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (70.97) | 18.7374 |
| 1990's | 3 (9.68) | 18.2507 |
| 2000's | 4 (12.90) | 29.6817 |
| 2010's | 1 (3.23) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Campisi, I | 1 |
| Granata, OM | 1 |
| Cocciadiferro, L | 1 |
| Calabrò, M | 1 |
| Polito, LM | 1 |
| Carruba, G | 1 |
| Loukovaara, M | 1 |
| Carson, M | 1 |
| Adlercreutz, H | 2 |
| Wang, R | 1 |
| Liu, Y | 1 |
| Sun, H | 1 |
| Wang, T | 1 |
| Li, C | 1 |
| Fan, J | 1 |
| Wang, Z | 1 |
| Abou-Salim, MA | 1 |
| Shaaban, MA | 1 |
| Abd El Hameid, MK | 1 |
| Elshaier, YAMM | 1 |
| Halaweish, F | 1 |
| BARDI, U | 1 |
| BORETTI, G | 1 |
| DI MARCO, A | 1 |
| BROWN, JB | 1 |
| CREAN, GP | 1 |
| GINSBURG, J | 1 |
| PULLINGER, BD | 1 |
| HEAD, MA | 1 |
| Hsu, JF | 1 |
| Chang, YC | 1 |
| Chen, TH | 1 |
| Lin, LC | 1 |
| Liao, PC | 1 |
| Yamamoto, T | 1 |
| Sakai, C | 1 |
| Yamaki, J | 1 |
| Takamori, K | 1 |
| Yoshiji, S | 1 |
| Kitawaki, J | 1 |
| Fujii, M | 1 |
| Yasuda, J | 1 |
| Honjo, H | 1 |
| Okada, H | 1 |
| Coombes, RC | 1 |
| Chilvers, C | 1 |
| Dowsett, M | 1 |
| Gazet, JC | 1 |
| Ford, HT | 1 |
| Bettelheim, R | 1 |
| Gordon, C | 1 |
| Smith, IE | 1 |
| Zava, D | 1 |
| Powles, TJ | 1 |
| Morgan, RT | 1 |
| Woods, LK | 1 |
| Moore, GE | 1 |
| McGavran, L | 1 |
| Quinn, LA | 1 |
| Semple, TU | 1 |
| Manesis, EK | 1 |
| Giannoulis, G | 1 |
| Zoumboulis, P | 1 |
| Vafiadou, I | 1 |
| Hadziyannis, SJ | 1 |
| Agarwal, VR | 1 |
| Takayama, K | 1 |
| Van Wyk, JJ | 1 |
| Sasano, H | 2 |
| Simpson, ER | 1 |
| Bulun, SE | 1 |
| Narasaka, T | 1 |
| Moriya, T | 1 |
| Endoh, M | 1 |
| Suzuki, T | 1 |
| Shizawa, S | 1 |
| Mizokami, Y | 1 |
| Matsuoka, T | 1 |
| Browne-Martin, K | 1 |
| Longcope, C | 1 |
| Uriel, J | 2 |
| Aussel, C | 1 |
| Bouillon, D | 1 |
| Loisillier, F | 1 |
| de Nechaud, B | 2 |
| Kew, MC | 1 |
| Kirschner, MA | 1 |
| Abrahams, GE | 1 |
| Katz, M | 1 |
| Gessner, T | 2 |
| Noble, RL | 1 |
| Guéchot, J | 1 |
| Peigney, N | 1 |
| Ballet, F | 1 |
| Vaubourdolle, M | 1 |
| Giboudeau, J | 1 |
| Poupon, R | 1 |
| Nagasue, N | 1 |
| Ogawa, Y | 1 |
| Yukaya, H | 1 |
| Ohta, N | 1 |
| Ito, A | 1 |
| Dao, TL | 1 |
| Libby, PR | 1 |
| Marks, F | 1 |
| Süss, R | 1 |
| Morris, HP | 1 |
| Hecker, E | 1 |
| Savu, L | 2 |
| Crepy, O | 2 |
| Judas, O | 2 |
| Emmelot, P | 1 |
| Bos, CJ | 1 |
| Dupiers, M | 1 |
| Nunez, E | 1 |
| Vallette, G | 1 |
| Benassayag, C | 1 |
| Jayle, MF | 2 |
| Lacassagne, A | 1 |
| Hurst, L | 1 |
| Ducret, MA | 1 |
1 review available for estrone and Liver Neoplasms
| Article | Year |
|---|---|
Oestrogen metabolism in liver disease.
Topics: Animals; Estradiol; Estriol; Estrogens; Estrogens, Conjugated (USP); Estrone; Female; Guinea Pigs; H | 1970 |
2 trials available for estrone and Liver Neoplasms
| Article | Year |
|---|---|
Adjuvant aminoglutethimide therapy for postmenopausal patients with primary breast cancer: progress report.
Topics: Adult; Aged; Aminoglutethimide; Breast Neoplasms; Clinical Trials as Topic; Dehydroepiandrosterone; | 1982 |
Treatment of hepatocellular carcinoma with combined suppression and inhibition of sex hormones: a randomized, controlled trial.
Topics: Analysis of Variance; Androgens; Carcinoma, Hepatocellular; Double-Blind Method; Drug Therapy, Combi | 1995 |
28 other studies available for estrone and Liver Neoplasms
| Article | Year |
|---|---|
16alpha-hydroxyestrone inhibits estrogen sulfotransferase activity in human liver cancer cells.
Topics: Cell Line, Tumor; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Humans; Hydroxyestrones; | 2009 |
Regulation of sex-hormone-binding globulin production by endogenous estrogens in vitro.
Topics: 2-Methoxyestradiol; Carcinoma, Hepatocellular; Estradiol; Estriol; Estrogens; Estrone; Humans; Hydro | 1995 |
Estradiol is significantly associated with prognosis in non-surgical liver cancer patients: from bench to bedside.
Topics: Adult; Aged; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Black or African American; Carcinoma, He | 2021 |
Design, synthesis and biological study of hybrid drug candidates of nitric oxide releasing cucurbitacin-inspired estrone analogs for treatment of hepatocellular carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cucurbitacins; Drug Design; Drug Screening Assays, | 2019 |
Influence of some steroids on the metabolism of rat liver mitochondria and of hepatoma ascites cells in vitro.
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Desoxycorticosterone; Estradiol; Estrone; Hydrocortison | 1962 |
OESTROGEN METABOLISM AND EXCRETION IN LIVER DISEASE.
Topics: Aged; Estradiol; Estriol; Estrogens; Estrone; Humans; Jaundice; Jaundice, Obstructive; Liver Cirrhos | 1964 |
HEPATOMA IN INTACT C3HF MALE AND VIRGIN FEMALE MICE AND AFTER GONADECTOMY ALONE OR SEBSEQUENT TREATMENT WITH OESTROGEN.
Topics: Animals; Body Weight; Breast Neoplasms; Carcinoma, Hepatocellular; Castration; Diet; Estradiol; Estr | 1964 |
Evaluation of electrospray ionization and atmospheric pressure chemical ionization for simultaneous detection of estrone and its metabolites using high-performance liquid chromatography/tandem mass spectrometry.
Topics: Atmospheric Pressure; Cell Line, Tumor; Chromatography, High Pressure Liquid; Culture Media; Estrone | 2007 |
Estrogen biosynthesis in human liver--a comparison of aromatase activity for C-19 steroids in fetal liver, adult liver and hepatoma tissues of human subjects.
Topics: Aged; Aromatase; Carcinoma, Hepatocellular; Estradiol; Estriol; Estrogens; Estrone; Fetus; Gestation | 1984 |
A human gallbladder adenocarcinoma cell line.
Topics: Adenocarcinoma; Aged; Cell Division; Cell Line; Cell Membrane; Cell Nucleus; Cytoplasm; Estrone; Fem | 1981 |
Molecular basis of severe gynecomastia associated with aromatase expression in a fibrolamellar hepatocellular carcinoma.
Topics: Adolescent; Androstenedione; Aromatase; Carcinoma, Hepatocellular; Estradiol; Estrone; Follicle Stim | 1998 |
17Beta-hydroxysteroid dehydrogenase type 2 and dehydroepiandrosterone sulfotransferase in the human liver.
Topics: 17-Hydroxysteroid Dehydrogenases; Aged; Carcinoma, Hepatocellular; Cholangiocarcinoma; Dehydroepiand | 2000 |
Regulation of sex hormone-binding globulin secretion in human hepatoma G2 cells.
Topics: Antineoplastic Agents, Hormonal; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Estrad | 2001 |
Liver differentiation and the estrogen-binding properties of alpha-fetoprotein.
Topics: Adenoma, Bile Duct; alpha-Fetoproteins; Animals; Animals, Newborn; Binding Sites; Carcinoma; Carcino | 1975 |
Mechanism of feminization in primary liver cancer.
Topics: Adult; Chorionic Gonadotropin; Dehydroepiandrosterone; Estradiol; Estriol; Estrogens; Estrone; Femin | 1977 |
A comparison of steroid glucuronlytransferases of rat liver and hepatoma, and effects of phenobarbitone and 3-methylcholanthrene induction.
Topics: Animals; Carcinoma, Hepatocellular; Enzyme Induction; Estradiol; Estrone; Glucuronosyltransferase; K | 1976 |
Occurrence of steroid glucuronyltransferases in a hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Estradiol; Estrone; Glucuronates; Glucuronosyltransferase; Hexos | 1977 |
Hormonal control of growth and progression in tumors of Nb rats and a theory of action.
Topics: Adrenal Gland Neoplasms; Animals; Estrogens; Estrone; Female; Kidney Neoplasms; Liver Neoplasms; Mal | 1977 |
Sex hormone imbalance in male alcoholic cirrhotic patients with and without hepatocellular carcinoma.
Topics: Aged; Carcinoma, Hepatocellular; Dihydrotestosterone; Estradiol; Estrone; Gonadal Steroid Hormones; | 1988 |
Serum levels of estrogens and testosterone in cirrhotic men with and without hepatocellular carcinoma.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Estradiol; Estriol; Estrogens; Estrone; Humans; Liver Cirrho | 1985 |
Conjugation of steroid hormones by breast cancer tissue and selection of patients for adrenalectomy.
Topics: Adrenalectomy; Aged; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Humans; Liver; Li | 1969 |
Metabolism and mechanism of action of estrogens. IX. Metabolism of estrone by microsomes from rat liver and transplanted hepatocellular carcinomas including minimal deviation (Morris 5123 C, 7800, 9121) hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Estradiol; Estrone; Liver; Liver Neoplasms; Microsomes; Neoplasm | 1967 |
[Formation of 2-methoxy derivatives by incubation of estrone 6,-7 3H with liver slices of normal hyperthyroid or hypothyroid rats and with rat hepatoma slices].
Topics: Animals; Carcinoma, Hepatocellular; Chromatography; Estrogens, Conjugated (USP); Estrone; Female; Hy | 1970 |
Studies on plasma membranes. XV. A sex difference in alkaline phosphatase activities of plasma membranes isolated from rat liver.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Calcium; Carcinogens; Carcinoma, Hepatocellular; Ca | 1971 |
Estrogen-binding properties of rat, mouse and man fetospecific serum proteins. Demonstration by immuno-autoradiographic methods.
Topics: Animals; Autoradiography; Blood Proteins; Carbon Isotopes; Carcinoma, Hepatocellular; Esterases; Est | 1972 |
Comparative study on the binding of estrogens by human and rat serum proteins in development.
Topics: Aging; Animals; Binding Sites; Blood; Blood Proteins; Carcinoma, Hepatocellular; Chromatography, Gel | 1974 |
[Influence exercised by different estrogens on the cancerization of rat liver by para-dimethyl-amino-azobenzene (DAB)].
Topics: 17-Ketosteroids; Animals; Estradiol; Estranes; Estrogens; Estrone; Liver Neoplasms; Male; Neoplasms, | 1968 |
[Incubation of 17 alpha estradiol-6,7-3H and 17 beta estradiol-6,7-3H in the presence of rat and rabbit liver slices].
Topics: Animals; Estradiol; Estriol; Estrone; Female; Glucuronates; Liver; Liver Neoplasms; Rabbits; Rats; S | 1969 |