Page last updated: 2024-11-07

estrone and Liver Cirrhosis

estrone has been researched along with Liver Cirrhosis in 36 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"Oestrone (E1), oestradiol (E2), testosterone (T), androstenedione (A) and cortisol (F) as well as LH and the percentage of binding of E1, E2, T and F in plasma were measured and compared in normal young and old male subjects and in male patients with fatty liver, chronic hepatitis and cirrhosis of the liver."3.65Steroid hormones and their binding in plasma of male patients with fatty liver, chronic hepatitis and liver cirrhosis. ( Kley, HK; Krüskemper, HL; Nieschlag, E; Solbach, HG; Wiegelmann, W, 1975)
"In most mAG patients, muscle atrophy was accompanied by palmar erythema."1.29Biochemical and clinical study of muscle atrophy at thenar and hypothenar eminences in patients with cirrhosis. ( Iijima, T; Kaneko, K; Nambu, M, 1996)
"Estrone was significantly elevated in both groups of patients."1.27Serum levels of estrogens and testosterone in cirrhotic men with and without hepatocellular carcinoma. ( Ito, A; Nagasue, N; Ogawa, Y; Ohta, N; Yukaya, H, 1985)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199032 (88.89)18.7374
1990's2 (5.56)18.2507
2000's1 (2.78)29.6817
2010's1 (2.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sinclair, M1
Gow, PJ1
Angus, PW1
Hoermann, R1
Handelsman, DJ1
Wittert, G1
Martin, S1
Grossmann, M1
BROWN, JB1
CREAN, GP1
GINSBURG, J1
ADLERCREUTZ, H2
SCHAUMAN, KO1
SCHREPFER, R1
NICHOLAS, HJ1
Prost, O2
Ottignon, Y1
Rémy-Martin, A2
Vuitton, D1
Miguet, JP1
Adessi, GL2
Shaaban, MM1
Ghaneimah, SA1
Hammad, WA1
El-Sharkawy, MM1
Elwan, SI1
Ahmed, YA1
Jasonni, VM1
Bulletti, C1
Bolelli, GF1
Franceschetti, F1
Bonavia, M1
Ciotti, P1
Flamigni, C1
Zhukov, SA1
Khazanov, AI1
Gerasimov, GM1
Nicollier, M1
Burnod, J1
Fukuda, K1
Gluud, C1
Henriksen, HH1
Svenstrup, B1
Nakamuta, M1
Ohashi, M1
Goto, K1
Tanabe, Y1
Hiroshige, K1
Nawata, H1
Nambu, M1
Kaneko, K1
Iijima, T1
Narasaka, T1
Moriya, T1
Endoh, M1
Suzuki, T1
Shizawa, S1
Mizokami, Y1
Matsuoka, T1
Sasano, H1
Ohashi, T1
Saito, T1
Ohmori, H1
Kley, HK5
Krüskemper, HL4
Keck, E1
Franz, C1
Watson, D1
Longcope, C1
Honjo, H1
Strohmeyer, G1
Wiegelmann, W2
Nieschlag, E2
Southren, AL3
Gordon, GG3
Green, JR1
Mowat, NA1
Fisher, RA1
Anderson, DC1
Olivo, J2
Rafil, F1
Rafii, F1
Pentikäinen, PJ1
Pentikäinen, LA1
Azarnoff, DL1
Dujovne, CA1
Solbach, HG1
Lopez del Pino, V1
Bolt, HM1
De Besi, L1
Zucchetta, P1
Zotti, S1
Mastrogiacomo, I1
Grün, R1
Nagasue, N1
Ogawa, Y1
Yukaya, H1
Ohta, N1
Ito, A1
Breuer, J1
Breuer, H1
Hellman, L2
Zumoff, B2
Fishman, J2
Gallagher, TF2
Levin, J1
Wenzel, M1
Blum, KU1
Kraas, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Concentration of Estrogen and Testosterone Ratio in Male Patients With Cirrhosis and Hypotension Compared to Male Cirrhosis Patients Without Hypotension[NCT05051293]0 participants (Actual)Observational2021-08-22Withdrawn (stopped due to Study will be changed from prospective to retrospective)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for estrone and Liver Cirrhosis

ArticleYear
Plasma-estrogens and liver cirrhosis.
    Zeitschrift fur Gastroenterologie, 1979, Volume: 17, Issue:7

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Androgens; Chorionic Gonadotropin; Dexamethasone; Estra

1979
[Estrogen metabolism and enterohepatic circulation].
    Nihon rinsho. Japanese journal of clinical medicine, 1979, Jun-10, Volume: 37, Issue:6

    Topics: Enterohepatic Circulation; Estradiol; Estriol; Estrogens; Estrone; Female; Glucuronates; Humans; Liv

1979
[Liver cirrhosis and hyperestrogenism].
    Deutsche medizinische Wochenschrift (1946), 1976, Aug-27, Volume: 101, Issue:35

    Topics: Adult; Aged; Chemical Phenomena; Chemistry; Estradiol; Estrogens; Estrone; Fatty Liver; Gynecomastia

1976
Rhythms and testosterone metabolism.
    Journal of steroid biochemistry, 1975, Volume: 6, Issue:5

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Androstenedione; Animals; Circadian Rhythm; Estradiol;

1975
Oestrogen metabolism in liver disease.
    The Journal of endocrinology, 1970, Volume: 46, Issue:1

    Topics: Animals; Estradiol; Estriol; Estrogens; Estrogens, Conjugated (USP); Estrone; Female; Guinea Pigs; H

1970

Trials

1 trial available for estrone and Liver Cirrhosis

ArticleYear
High circulating oestrone and low testosterone correlate with adverse clinical outcomes in men with advanced liver disease.
    Liver international : official journal of the International Association for the Study of the Liver, 2016, Volume: 36, Issue:11

    Topics: Androgens; Australia; Body Composition; Bone Density; Estradiol; Estrone; Exercise; Hand Strength; H

2016

Other Studies

30 other studies available for estrone and Liver Cirrhosis

ArticleYear
OESTROGEN METABOLISM AND EXCRETION IN LIVER DISEASE.
    Gut, 1964, Volume: 5

    Topics: Aged; Estradiol; Estriol; Estrogens; Estrone; Humans; Jaundice; Jaundice, Obstructive; Liver Cirrhos

1964
EXCRETION OF OESTRONE AND OESTRIOL IN THE URINE OF SOME MALE SUBJECTS WITH THE DUBIN-JOHNSON SYNDROME AND LIVER CIRRHOSIS FOLLOWING ORAL ADMINISTRATION OF OESTRADIOL BENZOATE.
    Acta medica Scandinavica, 1964, Volume: 175

    Topics: Administration, Oral; Alkaline Phosphatase; Aspartate Aminotransferases; Benzoates; Bilirubin; Blood

1964
CHEMICAL DETERMINATION OF PLASMA ESTROGENS.
    American journal of obstetrics and gynecology, 1965, Jul-15, Volume: 92

    Topics: Blood Chemical Analysis; Contraceptive Agents, Female; Estradiol; Estriol; Estrogens; Estrone; Femal

1965
Steroid sulfatase activities in normal and cirrhotic livers and plasma levels of estrone sulfate, estrone and estradiol-17 beta in men.
    Steroids, 1984, Volume: 43, Issue:2

    Topics: Adult; Aged; Antipyrine; Estradiol; Estrogens, Conjugated (USP); Estrone; Humans; Kinetics; Liver Ci

1984
Sex steroids in women with liver cirrhosis.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1980, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Amenorrhea; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Liver C

1980
Estrone sulfate, estrone and estradiol concentrations in normal and cirrhotic postmenopausal women.
    Steroids, 1983, Volume: 41, Issue:5

    Topics: Estradiol; Estrogens, Conjugated (USP); Estrone; Female; Humans; Liver Cirrhosis; Menopause; Radioim

1983
[Estrogen content of the blood of men with chronic hepatitis and liver cirrhosis in various phases of the disease].
    Voenno-meditsinskii zhurnal, 1984, Issue:10

    Topics: Adult; Estradiol; Estriol; Estrogens; Estrone; Hepatitis, Chronic; Humans; Liver Cirrhosis; Male; Mi

1984
Estrone sulfate concentrations in plasma of normal individuals, postmenopausal women with breast cancer, and men with cirrhosis.
    Clinical chemistry, 1983, Volume: 29, Issue:1

    Topics: Adult; Aged; Breast Neoplasms; Chromatography; Estrone; Female; Humans; Liver Cirrhosis; Male; Menop

1983
[Lower esophageal sphincter function and its clinical implication in liver cirrhosis (author's transl)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1981, Volume: 78, Issue:7

    Topics: Adult; Aged; Esophageal and Gastric Varices; Esophagogastric Junction; Estrone; Female; Gastrins; Hu

1981
Estrogens and portal hypertension in cirrhosis of the liver.
    The New England journal of medicine, 1981, Jan-01, Volume: 304, Issue:1

    Topics: Animals; Estradiol; Estrone; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Rats

1981
The re-evaluation of sex steroids metabolism in patients with non-alcoholic liver cirrhosis.
    Fukuoka igaku zasshi = Hukuoka acta medica, 1994, Volume: 85, Issue:6

    Topics: Aged; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; H

1994
Biochemical and clinical study of muscle atrophy at thenar and hypothenar eminences in patients with cirrhosis.
    Liver, 1996, Volume: 16, Issue:1

    Topics: Aged; Alanine Transaminase; Creatine; Creatinine; Electrolytes; Estradiol; Estriol; Estrone; Female;

1996
17Beta-hydroxysteroid dehydrogenase type 2 and dehydroepiandrosterone sulfotransferase in the human liver.
    Endocrine journal, 2000, Volume: 47, Issue:6

    Topics: 17-Hydroxysteroid Dehydrogenases; Aged; Carcinoma, Hepatocellular; Cholangiocarcinoma; Dehydroepiand

2000
Sequential radioimmunoassay of unconjugated and conjugated estrogen in male human plasma.
    Acta medica Okayama, 1979, Volume: 33, Issue:3

    Topics: Acute Kidney Injury; Estradiol; Estradiol Congeners; Estriol; Estrogens; Estrone; Humans; Kidney Fai

1979
Estrone and estradiol in patients with cirrhosis of the liver: effects of ACTH and dexamethasone.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 43, Issue:3

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Dexamethasone; Estradiol; Estrone; Humans; Liver

1976
Estrone sulfate and dehydroepiandrosterone sulfate concentrations in normal subjects and men with cirrhosis.
    Steroids, 1979, Volume: 34, Issue:5

    Topics: Adult; Aged; Dehydroepiandrosterone; Estrogens, Conjugated (USP); Estrone; Female; Humans; Liver Cir

1979
Effect of testosterone application on hormone concentrations of androgens and estrogens in male patients with cirrhosis of the liver.
    Gastroenterology, 1979, Volume: 76, Issue:2

    Topics: Adult; Androstenedione; Ascites; Estradiol; Estrone; Gynecomastia; Humans; Liver Cirrhosis; Male; Pr

1979
Plasma oestrogens in men with chronic liver disease.
    Gut, 1976, Volume: 17, Issue:6

    Topics: Adult; Chronic Disease; Estradiol; Estriol; Estrone; Fatty Liver; Gynecomastia; Hemochromatosis; Hum

1976
Conversion of androgens to estrogens in cirrhosis of the liver.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:6

    Topics: Adult; Androgens; Androstenedione; Estradiol; Estrogens; Estrone; Female; Follicle Stimulating Hormo

1975
Estrogen metabolism in hyperthyroidism and in cirrhosis of the liver.
    Steroids, 1975, Volume: 26, Issue:1

    Topics: Adult; Aged; Estradiol; Estrogens; Estrone; Female; Humans; Hyperthyroidism; Liver Cirrhosis; Male;

1975
Plasma levels and excretion of estrogens in urine in chronic lever disease.
    Gastroenterology, 1975, Volume: 69, Issue:1

    Topics: Adult; Aged; Alcoholism; Animals; Cattle; Chronic Disease; Estradiol; Estriol; Estrogens; Estrone; H

1975
Steroid hormones and their binding in plasma of male patients with fatty liver, chronic hepatitis and liver cirrhosis.
    Acta endocrinologica, 1975, Volume: 79, Issue:2

    Topics: Adult; Age Factors; Aged; Androstenedione; Chronic Disease; Estradiol; Estrone; Fatty Liver; Gynecom

1975
[The thioacetamide-poisoned rat as an animal experimental model for endocrinological studies of estrogen metabolism in chronic liver injury)].
    Endokrinologie, 1975, Volume: 66, Issue:3

    Topics: Acetamides; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chemical and Drug Induced Liver

1975
Sex hormones and sex hormone binding globulin in males with compensated and decompensated cirrhosis of the liver.
    Acta endocrinologica, 1989, Volume: 120, Issue:3

    Topics: Adult; Aged; Androstenedione; Estradiol; Estrone; Follicle Stimulating Hormone; Gonadal Steroid Horm

1989
[Growth hormone in females with liver cirrhosis].
    Zeitschrift fur Gastroenterologie, 1989, Volume: 27, Issue:6

    Topics: Adult; Aged; Estradiol; Estrone; Female; Growth Hormone; Hepatitis B; Hepatolenticular Degeneration;

1989
Serum levels of estrogens and testosterone in cirrhotic men with and without hepatocellular carcinoma.
    Gastroenterology, 1985, Volume: 88, Issue:3

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Estradiol; Estriol; Estrogens; Estrone; Humans; Liver Cirrho

1985
[Half-life of (4-14C)oestradiol-17beta in vivo, and metabolism of (4-14C)oestrone and (4-14C)oestriol in vitro in normal subjects and in patients with liver cirrhosis (author's transl)].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1973, Volume: 11, Issue:6

    Topics: Alanine Transaminase; Carbon Radioisotopes; Cell Fractionation; Chromatography, Paper; Cytosol; Estr

1973
Estradiol metabolism in total extrahepatic biliary obstruction.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:2

    Topics: 17-Ketosteroids; Alkaline Phosphatase; Bile Duct Neoplasms; Bilirubin; Cholestasis; Cholesterol; Col

1970
Reversible reproduction of the abnormal estradiol metabolism of biliary obstruction by administration of norethandrolone.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:5

    Topics: Aged; Cholestasis; Depression, Chemical; Estradiol; Estriol; Estrogens; Estrone; Female; Glucuronate

1970
[Inactivation of estradiol by oxidation following liver damage in rats and in patients with liver diseases].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1968, Volume: 6, Issue:4

    Topics: Aged; Amides; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Estra

1968