estrone has been researched along with Libman-Sacks Disease in 15 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), 17beta-estradiol was thought to play a dual pro- and antiinflammatory role depending on its concentration or probably conversion to downstream mitogenic 16 alpha-hydroxyestrone or naturally occurring antiestrogens such as 2-hydroxyestrone." | 3.72 | Patients with rheumatoid arthritis and systemic lupus erythematosus have increased renal excretion of mitogenic estrogens in relation to endogenous antiestrogens. ( Härle, P; Schedel, J; Schmidt, M; Schölmerich, J; Straub, RH; Weidler, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (66.67) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, WA | 1 |
| Cutolo, M | 1 |
| Weidler, C | 1 |
| Härle, P | 1 |
| Schedel, J | 1 |
| Schmidt, M | 1 |
| Schölmerich, J | 1 |
| Straub, RH | 1 |
| Bucala, R | 4 |
| Fishman, J | 7 |
| Cerami, A | 3 |
| Lahita, RG | 7 |
| Bradlow, HL | 4 |
| Kunkel, HG | 3 |
| Bradlow, L | 1 |
| McAlindon, TE | 1 |
| Gulin, J | 1 |
| Chen, T | 1 |
| Klug, T | 1 |
| Lahita, R | 1 |
| Nuite, M | 1 |
| Miller, MH | 1 |
| Urowitz, MB | 1 |
| Gladman, DD | 1 |
| Killinger, DW | 1 |
| Baer, AN | 1 |
| Green, FA | 1 |
| Carrabba, M | 1 |
| Giovine, C | 1 |
| Chevallard, M | 1 |
| Angelini, M | 1 |
| Ambrosi, B | 1 |
| Travaglini, P | 1 |
1 trial available for estrone and Libman-Sacks Disease
| Article | Year |
|---|---|
Indole-3-carbinol in women with SLE: effect on estrogen metabolism and disease activity.
Topics: Adult; Estrogen Antagonists; Estrogens; Female; Humans; Hydroxyestrones; Indoles; Lupus Erythematosu | 2001 |
14 other studies available for estrone and Libman-Sacks Disease
| Article | Year |
|---|---|
16 α-Hydroxyestrone induced adduct generate high affinity autoantibodies in SLE.
Topics: Adult; Antibody Affinity; Autoantibodies; Epitopes; Female; Histones; Humans; Hydroxyestrones; Kinet | 2019 |
Estrogen metabolites: increasing evidence for their role in rheumatoid arthritis and systemic lupus erythematosus.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Autoimmunity; Estrogens; Female; Humans; Hydroxyestrones | 2004 |
Patients with rheumatoid arthritis and systemic lupus erythematosus have increased renal excretion of mitogenic estrogens in relation to endogenous antiestrogens.
Topics: Arthritis, Rheumatoid; Estrogen Receptor Modulators; Estrogens; Female; Humans; Hydroxyestrones; Lup | 2004 |
Formation of covalent adducts between cortisol and 16 alpha-hydroxyestrone and protein: possible role in the pathogenesis of cortisol toxicity and systemic lupus erythematosus.
Topics: Acetylation; Chemical Phenomena; Chemistry; Estrone; Hydrocortisone; Hydroxyestrones; Lupus Erythema | 1982 |
Abnormal estrogen and androgen metabolism in the human with systemic lupus erythematosus.
Topics: Estradiol; Estriol; Estrone; Female; Humans; Hydroxyestrones; Hydroxylation; Lupus Erythematosus, Sy | 1982 |
Estrogen metabolism in systemic lupus erythematosus: patients and family members.
Topics: Estriol; Estrogens; Female; Humans; Hydroxyestrones; Lupus Erythematosus, Systemic; Male | 1982 |
Alterations of estrogen metabolism in systemic lupus erythematosus.
Topics: Adolescent; Adult; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Hydroxyestrones; Lupus Er | 1979 |
Anti-oestrogen antibodies in users of oral contraceptives and in patients with systemic lupus erythematosus.
Topics: Adult; Antibodies; Contraceptives, Oral; Enzyme-Linked Immunosorbent Assay; Estrogens; Female; Human | 1987 |
Increased levels of 16 alpha-hydroxyestrone-modified proteins in pregnancy and in systemic lupus erythematosus.
Topics: Adolescent; Adult; Amino Acids; Basement Membrane; Chemical Phenomena; Chemistry; Erythrocyte Membra | 1985 |
Determination of 16 alpha-hydroxyestrone by radioimmunoassay in systemic lupus erythematosus.
Topics: Adult; Estradiol; Estrone; Female; Humans; Hydroxyestrones; Lupus Erythematosus, Systemic; Male; Men | 1985 |
Systemic lupus erythematosus in males.
Topics: Adult; Aged; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; Female; HLA | 1983 |
Estrogen metabolism in the (New Zealand black x New Zealand white)F1 murine model of systemic lupus erythematosus.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Estrogens; Estrone; Hydroxylation; | 1990 |
Klinefelter's syndrome: hormone metabolism in hypogonadal males with systemic lupus erythematosus.
Topics: Androgens; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Hydroxylation; Klinefelter | 1987 |
Abnormalities of sex hormones in men with systemic lupus erythematosus.
Topics: Adult; Animals; Chorionic Gonadotropin; Estradiol; Estrone; Female; Humans; Lupus Erythematosus, Sys | 1985 |