Page last updated: 2024-11-07

estrone and Kidney Neoplasms

estrone has been researched along with Kidney Neoplasms in 22 studies

Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.

Kidney Neoplasms: Tumors or cancers of the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
"Olaparib treatment led to more severe autophagy and apoptosis in FLCN deficient ACHN-2 and UOK257 cells compared to the FLCN expressing ACHN and UOK257-F cells."1.62Folliculin deficient renal cancer cells exhibit BRCA1 A complex expression impairment and sensitivity to PARP1 inhibitor olaparib. ( Chen, Y; Li, J; Xia, Q; Xu, Y; Zhang, Q; Zhang, Z, 2021)
"BHD knockout mice developed enlarged polycystic kidneys and died from renal failure by 3 weeks of age."1.35Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys. ( Alvord, WG; Baba, M; Bernardo, M; Choyke, P; Furihata, M; Haines, DC; Hong, SB; Igarashi, P; Ileva, L; Leighty, R; Linehan, WM; Patel, V; Schmidt, LS; Southon, E; Tessarollo, L; Warren, MB; Yao, M; Zbar, B, 2008)
"In all, 10 RCCs were associated with breast carcinoma; 4, with endometrial carcinoma; and 3, with ovarian carcinoma."1.30Multiple primary tumors: 17 cases of renal-cell carcinoma associated with primary tumors involving different steroid-hormone target tissues. ( De Vico, A; Di Silverio, F; Flammia, GP; Mariani, M; Sciarra, A, 1997)
"Liver metastases of hormone-dependent adrenal carcinomas continued growth and could not be influenced by removal of estrogen, although the primary transplant regressed."1.26Hormonal control of growth and progression in tumors of Nb rats and a theory of action. ( Noble, RL, 1977)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19905 (22.73)18.7374
1990's3 (13.64)18.2507
2000's5 (22.73)29.6817
2010's6 (27.27)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Rizzati, V1
Rathahao, E1
Gamet-Payrastre, L1
Delous, G1
Jouanin, I1
Guéraud, F1
Paris, A1
Fostier, W1
Holt, G1
Sampson, J1
Rajan, N1
Zhang, Q2
Xu, Y1
Zhang, Z1
Li, J1
Xia, Q1
Chen, Y1
Radzikowska, E1
Lechowicz, U1
Winek, J1
Opoka, L1
Laviolette, LA1
Wilson, J1
Koller, J1
Neil, C1
Hulick, P1
Rejtar, T1
Karger, B1
Teh, BT1
Iliopoulos, O1
Bastola, P1
Stratton, Y1
Kellner, E1
Mikhaylova, O1
Yi, Y1
Sartor, MA1
Medvedovic, M1
Biesiada, J1
Meller, J1
Czyzyk-Krzeska, MF1
Si, S1
Schoen, S1
Chen, J1
Jin, XB1
Wu, G1
Yager, JD1
Drabkin, HA1
Gemmill, RM1
Zanatta, M1
Bettini, G1
Scarpa, F1
Fiorelli, F1
Rubini, G1
Mininni, AN1
Capitani, O1
Nickerson, ML1
Warren, MB2
Toro, JR1
Matrosova, V1
Glenn, G1
Turner, ML1
Duray, P1
Merino, M1
Choyke, P2
Pavlovich, CP1
Sharma, N1
Walther, M1
Munroe, D1
Hill, R1
Maher, E1
Greenberg, C1
Lerman, MI1
Linehan, WM2
Zbar, B2
Schmidt, LS2
DONTENWILL, W1
WRBA, H1
Nagy, A1
Zoubakov, D1
Stupar, Z1
Kovacs, G1
Baba, M1
Furihata, M1
Hong, SB1
Tessarollo, L1
Haines, DC1
Southon, E1
Patel, V1
Igarashi, P1
Alvord, WG1
Leighty, R1
Yao, M1
Bernardo, M1
Ileva, L1
Kim, EH1
Jeong, SY1
Kim, HJ1
Kim, YC1
Caviezel, M1
Lutz, WK1
Minini, U1
Schlatter, C1
Zhu, BT1
Evaristus, EN1
Antoniak, SK1
Sarabia, SF1
Ricci, MJ1
Liehr, JG1
Di Silverio, F1
Sciarra, A1
Flammia, GP1
Mariani, M1
De Vico, A1
Stack, DE1
Cavalieri, EL1
Rogan, EG1
Wahren, B1
Noble, RL1
Knapstein, P1
Wortmann, W1
Mappes, G1
Centurion, A1
Oertel, GW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevalence of Birt-Hogg-Dubé Syndrome Among Patients With (Hereditary) Spontaneous Pneumothorax[NCT02916992]Phase 1200 participants (Anticipated)Interventional2016-09-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for estrone and Kidney Neoplasms

ArticleYear
Mechanisms of estrogen carcinogenesis: The role of E2/E1-quinone metabolites suggests new approaches to preventive intervention--A review.
    Steroids, 2015, Volume: 99, Issue:Pt A

    Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Carcinogens; Disease Models, Animal; Estradiol;

2015
Obesity, cholesterol, and clear-cell renal cell carcinoma (RCC).
    Advances in cancer research, 2010, Volume: 107

    Topics: Adiponectin; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Renal Cell; Carrier Proteins;

2010

Other Studies

20 other studies available for estrone and Kidney Neoplasms

ArticleYear
In vitro aromatic bioactivation of the weak estrogen E(2)alpha and genesis of DNA adducts.
    Steroids, 2005, Volume: 70, Issue:3

    Topics: Adenocarcinoma; Animals; Catechols; Cattle; Cell Line, Tumor; Chromatography, High Pressure Liquid;

2005
Folliculin inactivation and cutaneous leiomyosarcoma in Birt-Hogg-Dubé syndrome.
    The British journal of dermatology, 2023, 03-30, Volume: 188, Issue:4

    Topics: Birt-Hogg-Dube Syndrome; Estrone; Humans; Kidney Neoplasms; Leiomyosarcoma; Skin Neoplasms

2023
Folliculin deficient renal cancer cells exhibit BRCA1 A complex expression impairment and sensitivity to PARP1 inhibitor olaparib.
    Gene, 2021, Feb-15, Volume: 769

    Topics: Animals; Antineoplastic Agents; BRCA1 Protein; Carcinoma, Renal Cell; Cell Line, Tumor; Estrone; Hum

2021
Novel folliculin gene mutations in Polish patients with Birt-Hogg-Dubé syndrome.
    Orphanet journal of rare diseases, 2021, 07-06, Volume: 16, Issue:1

    Topics: Angiomyolipoma; Birt-Hogg-Dube Syndrome; Estrone; Female; Humans; Kidney Neoplasms; Male; Mutation;

2021
Human folliculin delays cell cycle progression through late S and G2/M-phases: effect of phosphorylation and tumor associated mutations.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Animals; Carcinoma, Renal Cell; Cell Division; Cell Line, Tumor; Estrone; Fibroblasts; G2 Phase; Ger

2013
Folliculin contributes to VHL tumor suppressing activity in renal cancer through regulation of autophagy.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Animals; Autophagy; Blotting, Western; Estrone; Humans; In Vitro Techniques; Kidney Neoplasms; Mice;

2013
Suppression of autophagy enhances preferential toxicity of paclitaxel to folliculin-deficient renal cancer cells.
    Journal of experimental & clinical cancer research : CR, 2013, Dec-04, Volume: 32

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Ce

2013
Nodular dermatofibrosis in a dog without a renal tumour or a mutation in the folliculin gene.
    Journal of comparative pathology, 2013, Volume: 148, Issue:2-3

    Topics: Animals; Dog Diseases; Dogs; Estrone; Female; Kidney Neoplasms; Mutation; Skin Diseases

2013
Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dubé syndrome.
    Cancer cell, 2002, Volume: 2, Issue:2

    Topics: Amino Acid Sequence; Base Sequence; Chromosomes, Human, Pair 17; Conserved Sequence; DNA Mutational

2002
[The specific effect of estrone sulfate on tissue culture of a hormone-induced kidney tumor in the golden hamster].
    Klinische Wochenschrift, 1959, Jul-15, Volume: 37

    Topics: Animals; Contraceptive Agents, Female; Cricetinae; Estradiol Congeners; Estrogens; Estrone; Female;

1959
Lack of mutation of the folliculin gene in sporadic chromophobe renal cell carcinoma and renal oncocytoma.
    International journal of cancer, 2004, Apr-10, Volume: 109, Issue:3

    Topics: Adenoma, Oxyphilic; Carcinoma, Renal Cell; Chromosomes, Human, Pair 17; DNA Mutational Analysis; Est

2004
Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
    Journal of the National Cancer Institute, 2008, Jan-16, Volume: 100, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Blotting, Southern; Cell Proliferation; Disease Models, Animal

2008
A case of Birt-Hogg-Dubé syndrome.
    Journal of Korean medical science, 2008, Volume: 23, Issue:2

    Topics: Adult; Biopsy; Diagnosis, Differential; DNA Mutational Analysis; Estrone; Exons; Female; Gene Deleti

2008
Interaction of estrone and estradiol with DNA and protein of liver and kidney in rat and hamster in vivo and in vitro.
    Archives of toxicology, 1984, Volume: 55, Issue:2

    Topics: Animals; Cricetinae; DNA; Estradiol; Estrogens; Estrone; Female; In Vitro Techniques; Kidney; Kidney

1984
Metabolic deglucuronidation and demethylation of estrogen conjugates as a source of parent estrogens and catecholestrogen metabolites in Syrian hamster kidney, a target organ of estrogen-induced tumorigenesis.
    Toxicology and applied pharmacology, 1996, Volume: 136, Issue:1

    Topics: 2-Methoxyestradiol; Animals; Cell Fractionation; Cricetinae; Estradiol; Estrogens, Conjugated (USP);

1996
Multiple primary tumors: 17 cases of renal-cell carcinoma associated with primary tumors involving different steroid-hormone target tissues.
    World journal of urology, 1997, Volume: 15, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma, Renal Cell; Endometrial Neoplasms; Estradiol; Estrone; Fem

1997
Catecholestrogens as procarcinogens: depurinating adducts and tumor initiation.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: Animals; Carcinogens; Catechol O-Methyltransferase; Cricetinae; Estradiol; Estrogens, Catechol; Estr

1998
Tumour markers in urology: aids in cancer diagnosis and management.
    Urological research, 1979, Jun-22, Volume: 7, Issue:2

    Topics: Acid Phosphatase; Alkaline Phosphatase; alpha 1-Antitrypsin; alpha-Fetoproteins; Antibodies, Neoplas

1979
Hormonal control of growth and progression in tumors of Nb rats and a theory of action.
    Cancer research, 1977, Volume: 37, Issue:1

    Topics: Adrenal Gland Neoplasms; Animals; Estrogens; Estrone; Female; Kidney Neoplasms; Liver Neoplasms; Mal

1977
[Estrone metabolism in the human liver in vivo].
    Archiv fur Gynakologie, 1971, Jun-04, Volume: 211, Issue:1

    Topics: Adult; Estrone; Female; Humans; Kidney Neoplasms; Liver; Perfusion; Tritium

1971