estrone has been researched along with Insulin Sensitivity in 23 studies
Hydroxyestrones: Estrone derivatives substituted with one or more hydroxyl groups in any position. They are important metabolites of estrone and other estrogens.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with metformin or rosiglitazone prevents excess adrenal androgen synthesis." | 5.34 | Novel endocrine disrupter effects of classic and atypical antipsychotic agents and divalproex: induction of adrenal hyperandrogenism, reversible with metformin or rosiglitazone. ( Bahtiyar, G; Sacerdote, AS; Weiss, K, 2007) |
| " The relationships between total testosterone, dihydrotestosterone, estrone, estradiol, sex hormone-binding globulin (SHBG), the homeostasis model assessment for insulin resistance (HOMA-IR), and each lipid variable were explored using multivariable linear regression." | 3.79 | Endogenous estrogen and androgen levels are not independent predictors of lipid levels in postmenopausal women. ( Bell, RJ; Davis, SR; Moufarege, A; Robinson, PJ; Worsley, R, 2013) |
| "Low levels of total testosterone, testosterone/estradiol ratio and free androgen index and higher levels of estrone in men with coronary artery disease appear together with many features of metabolic syndrome and may be involved in the pathogenesis of coronary atherosclerosis." | 3.72 | Evaluation of sex hormone levels and some metabolic factors in men with coronary atherosclerosis. ( Dunajska, K; Jêdrzejuk, D; Kuliczkowski, W; Milewicz, A; Nowicki, P; Salomon, P; Szymczak, J, 2004) |
| "Information about the chemical constituents of SJHK were collected, and druggable compounds were screened based on oral bioavailability and drug-likeness." | 1.72 | Network pharmacology and molecular docking approaches to elucidate the potential compounds and targets of Saeng-Ji-Hwang-Ko for treatment of type 2 diabetes mellitus. ( Ahn, D; Chung, SJ; Jeong, S; Kim, H; Kim, HH; Kim, Y; Ko, M, 2022) |
| "Two groups of breast cancer patients (53±2 years) in clinical remission receiving no specific therapy were examined: group 1, with BRCA1 gene mutations (N=11) and group 2, without mutations of this kind (N=11)." | 1.38 | Endocrine metabolic disorders in patients with breast cancer, carriers of BRCA1 gene mutations. ( Berstein, LM; Boyarkina, MP; Imyanitov, EN; Kovalenko, IG; Poroshina, TE; Semiglazov, VF; Vasilyev, DA, 2012) |
| " After an overnight fast, euglycemic-hyperinsulinemic clamp studies were performed 2 hours after single oral dosing as follows: (1) A-348441 at 100 mg/kg or (2) vehicle." | 1.34 | Liver-selective glucocorticoid receptor antagonism decreases glucose production and increases glucose disposal, ameliorating insulin resistance. ( Jacobson, P; Mika, A; Nguyen, P; Ohman, L; Opgenorth, T; von Geldern, TW; Wilcox, D; Zinker, B, 2007) |
| "Treatment with metformin or rosiglitazone prevents excess adrenal androgen synthesis." | 1.34 | Novel endocrine disrupter effects of classic and atypical antipsychotic agents and divalproex: induction of adrenal hyperandrogenism, reversible with metformin or rosiglitazone. ( Bahtiyar, G; Sacerdote, AS; Weiss, K, 2007) |
| "In vivo insulin resistance was observed in both nonobese (P less than 0." | 1.28 | Insulin and insulin-like growth factor-I responsiveness in polycystic ovarian syndrome. ( Bergman, RN; Bersch, N; Buyalos, RP; Geffner, ME; Golde, DW; Judd, HL; Watanabe, RM, 1992) |
| "Diazoxide treatment resulted in suppressed insulin release during a 100-g oral glucose tolerance test (insulin area under the curve, 262 +/- 55 nmol/min." | 1.28 | A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome. ( Blackard, WG; Clore, JN; Matt, DW; Nestler, JE; Plymate, SR; Powers, LP; Rittmaster, RS; Steingold, KA, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 9 (39.13) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Berstein, LM | 1 |
| Boyarkina, MP | 1 |
| Vasilyev, DA | 1 |
| Poroshina, TE | 1 |
| Kovalenko, IG | 1 |
| Imyanitov, EN | 1 |
| Semiglazov, VF | 1 |
| Aladhami, AK | 1 |
| Unger, CA | 1 |
| Hope, MC | 1 |
| Cotham, WE | 1 |
| Velázquez, KT | 1 |
| Enos, RT | 1 |
| Ko, M | 1 |
| Kim, Y | 1 |
| Kim, HH | 1 |
| Jeong, S | 1 |
| Ahn, D | 1 |
| Chung, SJ | 1 |
| Kim, H | 1 |
| Marlatt, KL | 1 |
| Redman, LM | 1 |
| Beyl, RA | 1 |
| Smith, SR | 1 |
| Champagne, CM | 1 |
| Yi, F | 1 |
| Lovejoy, JC | 1 |
| Eriksson, AL | 1 |
| Perry, JRB | 1 |
| Coviello, AD | 1 |
| Delgado, GE | 1 |
| Ferrucci, L | 1 |
| Hoffman, AR | 1 |
| Huhtaniemi, IT | 1 |
| Ikram, MA | 1 |
| Karlsson, MK | 1 |
| Kleber, ME | 1 |
| Laughlin, GA | 1 |
| Liu, Y | 1 |
| Lorentzon, M | 1 |
| Lunetta, KL | 1 |
| Mellström, D | 1 |
| Murabito, JM | 1 |
| Murray, A | 1 |
| Nethander, M | 1 |
| Nielson, CM | 1 |
| Prokopenko, I | 1 |
| Pye, SR | 1 |
| Raffel, LJ | 1 |
| Rivadeneira, F | 1 |
| Srikanth, P | 1 |
| Stolk, L | 1 |
| Teumer, A | 1 |
| Travison, TG | 1 |
| Uitterlinden, AG | 1 |
| Vaidya, D | 1 |
| Vanderschueren, D | 1 |
| Zmuda, JM | 1 |
| März, W | 1 |
| Orwoll, ES | 1 |
| Ouyang, P | 1 |
| Vandenput, L | 1 |
| Wu, FCW | 1 |
| de Jong, FH | 1 |
| Bhasin, S | 1 |
| Kiel, DP | 1 |
| Ohlsson, C | 1 |
| Karateke, A | 1 |
| Dokuyucu, R | 1 |
| Dogan, H | 1 |
| Ozgur, T | 1 |
| Tas, ZA | 1 |
| Tutuk, O | 1 |
| Agturk, G | 1 |
| Tumer, C | 1 |
| Mak, TCS | 1 |
| Livingstone, DEW | 1 |
| Nixon, M | 1 |
| Walker, BR | 1 |
| Andrew, R | 1 |
| Worsley, R | 1 |
| Robinson, PJ | 1 |
| Bell, RJ | 1 |
| Moufarege, A | 1 |
| Davis, SR | 1 |
| Villarroel, C | 1 |
| Salinas, A | 1 |
| López, P | 1 |
| Kohen, P | 1 |
| Rencoret, G | 1 |
| Devoto, L | 1 |
| Codner, E | 1 |
| Braunstein, GD | 1 |
| Johnson, BD | 1 |
| Stanczyk, FZ | 1 |
| Bittner, V | 1 |
| Berga, SL | 1 |
| Shaw, L | 1 |
| Hodgson, TK | 1 |
| Paul-Labrador, M | 1 |
| Azziz, R | 1 |
| Merz, CN | 1 |
| Remesar, X | 1 |
| Fernández-López, JA | 2 |
| Alemany, M | 2 |
| Persky, V | 1 |
| Piorkowski, J | 1 |
| Turyk, M | 1 |
| Freels, S | 1 |
| Chatterton, R | 1 |
| Dimos, J | 1 |
| Bradlow, HL | 1 |
| Chary, LK | 1 |
| Burse, V | 1 |
| Unterman, T | 1 |
| Sepkovic, D | 1 |
| McCann, K | 1 |
| Goss, AM | 1 |
| Darnell, BE | 1 |
| Brown, MA | 1 |
| Oster, RA | 1 |
| Gower, BA | 1 |
| Dunajska, K | 1 |
| Milewicz, A | 1 |
| Szymczak, J | 1 |
| Jêdrzejuk, D | 1 |
| Kuliczkowski, W | 1 |
| Salomon, P | 1 |
| Nowicki, P | 1 |
| Ferrer-Lorente, R | 1 |
| Cabot, C | 1 |
| Zinker, B | 1 |
| Mika, A | 1 |
| Nguyen, P | 1 |
| Wilcox, D | 1 |
| Ohman, L | 1 |
| von Geldern, TW | 1 |
| Opgenorth, T | 1 |
| Jacobson, P | 1 |
| Bahtiyar, G | 1 |
| Weiss, K | 1 |
| Sacerdote, AS | 1 |
| Igwebuike, A | 1 |
| Irving, BA | 1 |
| Bigelow, ML | 1 |
| Short, KR | 1 |
| McConnell, JP | 1 |
| Nair, KS | 1 |
| Dunaif, A | 1 |
| Scott, D | 1 |
| Finegood, D | 1 |
| Quintana, B | 1 |
| Whitcomb, R | 1 |
| Collison, M | 1 |
| Campbell, IW | 1 |
| Salt, IP | 1 |
| Dominiczak, AF | 1 |
| Connell, JM | 1 |
| Lyall, H | 1 |
| Gould, GW | 1 |
| Buyalos, RP | 1 |
| Geffner, ME | 1 |
| Bersch, N | 1 |
| Judd, HL | 1 |
| Watanabe, RM | 1 |
| Bergman, RN | 1 |
| Golde, DW | 1 |
| Nestler, JE | 1 |
| Powers, LP | 1 |
| Matt, DW | 1 |
| Steingold, KA | 1 |
| Plymate, SR | 1 |
| Rittmaster, RS | 1 |
| Clore, JN | 1 |
| Blackard, WG | 1 |
| Billiar, RB | 1 |
| Richardson, D | 1 |
| Schwartz, R | 1 |
| Posner, B | 1 |
| Little, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Descriptive, Transversal Study of Evaluation of Cardiovascular Risks Factors and Prevalence of Metabolic Syndrome in the Different Phenotypes of Women With Polycystic Ovary Syndrome[NCT00784615] | 80 participants (Anticipated) | Observational | 2007-12-31 | Recruiting | |||
| Clinical Metabolic and Endocrine Parameters in Response to Metformin and Lifestyle Intervention in Women With Polycystic Ovary Syndrome: A Phase 4 Randomized, Double- Blind and Placebo Control Trial[NCT00679679] | Phase 4 | 30 participants (Actual) | Interventional | 2003-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for estrone and Insulin Sensitivity
| Article | Year |
|---|---|
Oleoyl-estrone.
Topics: Animals; Energy Metabolism; Estrone; Humans; Insulin Resistance; Lipoproteins; Obesity; Oleic Acids; | 2012 |
2 trials available for estrone and Insulin Sensitivity
| Article | Year |
|---|---|
Lack of dehydroepiandrosterone effect on a combined endurance and resistance exercise program in postmenopausal women.
Topics: Aged; Blood Glucose; Body Composition; Cholesterol; Dehydroepiandrosterone; Dehydroepiandrosterone S | 2008 |
The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome.
Topics: Adult; Body Mass Index; Chromans; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Double-Bli | 1996 |
20 other studies available for estrone and Insulin Sensitivity
| Article | Year |
|---|---|
Endocrine metabolic disorders in patients with breast cancer, carriers of BRCA1 gene mutations.
Topics: Blood Glucose; BRCA1 Protein; Breast Neoplasms; C-Peptide; Endocrine System; Estradiol; Female; Huma | 2012 |
Augmenting Skeletal Muscle Estrogen Does not Prevent or Rescue Obesity-linked Metabolic Impairments in Female Mice.
Topics: Animals; Aromatase; Diet, High-Fat; Estradiol; Estrogens; Estrone; Female; Glucose; Inflammation; In | 2022 |
Network pharmacology and molecular docking approaches to elucidate the potential compounds and targets of Saeng-Ji-Hwang-Ko for treatment of type 2 diabetes mellitus.
Topics: Cyclooxygenase 2; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Estrogens; Estrone; Humans; Insu | 2022 |
Racial differences in body composition and cardiometabolic risk during the menopause transition: a prospective, observational cohort study.
Topics: Adiposity; Black or African American; Blood Glucose; Blood Pressure; Body Weight; Cholesterol, HDL; | 2020 |
Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men.
Topics: Aromatase; Bone Density; Chromosomes, Human, X; Cohort Studies; Estradiol; Estrone; Female; Gene Exp | 2018 |
Investigation of Therapeutic Effects of Erdosteine on Polycystic Ovary Syndrome in a Rat Model.
Topics: Analysis of Variance; Animals; Blood Glucose; Cholesterol; Disease Models, Animal; Estrone; Expector | 2018 |
Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice.
Topics: Animals; Cholestenone 5 alpha-Reductase; Cholic Acids; Diet, High-Fat; Dutasteride; Estrone; Glucone | 2019 |
Endogenous estrogen and androgen levels are not independent predictors of lipid levels in postmenopausal women.
Topics: Androgens; Cholesterol, HDL; Cholesterol, LDL; Cross-Sectional Studies; Dihydrotestosterone; Estradi | 2013 |
Pregestational type 2 diabetes and gestational diabetes exhibit different sexual steroid profiles during pregnancy.
Topics: Adult; Androstenedione; Chile; Dehydroepiandrosterone Sulfate; Diabetes Mellitus, Type 2; Diabetes, | 2017 |
Relations between endogenous androgens and estrogens in postmenopausal women with suspected ischemic heart disease.
Topics: Adult; Aged; Aged, 80 and over; Androgens; Androstenedione; Body Mass Index; Chest Pain; Coronary An | 2008 |
Associations of polychlorinated biphenyl exposure and endogenous hormones with diabetes in post-menopausal women previously employed at a capacitor manufacturing plant.
Topics: Aged; Body Mass Index; C-Reactive Protein; Cholesterol; Cohort Studies; Dehydroepiandrosterone Sulfa | 2011 |
Longitudinal associations of the endocrine environment on fat partitioning in postmenopausal women.
Topics: Absorptiometry, Photon; Aging; Body Fat Distribution; Estradiol; Estrone; Female; Hormone Replacemen | 2012 |
Evaluation of sex hormone levels and some metabolic factors in men with coronary atherosclerosis.
Topics: Adult; Blood Glucose; Body Mass Index; Coronary Artery Disease; Estrone; Gonadal Steroid Hormones; H | 2004 |
Combined effects of oleoyl-estrone and a beta3-adrenergic agonist (CL316,243) on lipid stores of diet-induced overweight male Wistar rats.
Topics: 3-Hydroxybutyric Acid; Adrenergic beta-Agonists; Analysis of Variance; Animals; Blood Glucose; Dioxo | 2005 |
Liver-selective glucocorticoid receptor antagonism decreases glucose production and increases glucose disposal, ameliorating insulin resistance.
Topics: Animals; Blood Glucose; Cholic Acids; Dose-Response Relationship, Drug; Estrone; Glucose; Insulin; I | 2007 |
Novel endocrine disrupter effects of classic and atypical antipsychotic agents and divalproex: induction of adrenal hyperandrogenism, reversible with metformin or rosiglitazone.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adrenal Glands; Adult; Aged; Antipsychotic Agents; Cortodo | 2007 |
Sex hormones induce insulin resistance in 3T3-L1 adipocytes by reducing cellular content of IRS proteins.
Topics: 3-O-Methylglucose; 3T3 Cells; Adipocytes; Animals; Biological Transport; Deoxyglucose; Estradiol; Es | 2000 |
Insulin and insulin-like growth factor-I responsiveness in polycystic ovarian syndrome.
Topics: Adult; Analysis of Variance; Androgens; Cell Line, Transformed; Colony-Forming Units Assay; Estradio | 1992 |
A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome.
Topics: Adult; Androstane-3,17-diol; Androstenedione; Diazoxide; Estradiol; Estrone; Female; Glucose Toleran | 1991 |
A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome.
Topics: Adult; Androstane-3,17-diol; Androstenedione; Diazoxide; Estradiol; Estrone; Female; Glucose Toleran | 1991 |
A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome.
Topics: Adult; Androstane-3,17-diol; Androstenedione; Diazoxide; Estradiol; Estrone; Female; Glucose Toleran | 1991 |
A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome.
Topics: Adult; Androstane-3,17-diol; Androstenedione; Diazoxide; Estradiol; Estrone; Female; Glucose Toleran | 1991 |
Effect of chronically elevated androgen or estrogen on the glucose tolerance test and insulin response in female rhesus monkeys.
Topics: Androstenedione; Animals; C-Peptide; Estradiol; Estrone; Female; Glucose Tolerance Test; Insulin; In | 1987 |